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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IL21 HGNC:6005 (HGNC)
59067 (Entrez Gene)
605384 (OMIM)
Interleukin 21 (MyGene.info)
HGNC homology
Chr4 q27 Chr4:122612628-122621057 (-)
common variable immunodeficiency
Q9HBE4 (UniProt | EBI)
NM_001207006 (RefSeq)
mouse Il21 MGI:1890474 (MGI)
60505 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 18.36 cM Chr3:37222759-37232636 (-)
OTTMUSG00000007350 (VEGA)
OTTMUSP00000048827 (VEGA)
OTTMUST00000089349 (VEGA)
rat Il21 365769 (Entrez Gene)
Chr2 q25 A3QPB9 (UniProt | EBI)
NM_001108943 (RefSeq)
chimpanzee IL21 471295 (Entrez Gene)
Chr4 XP_526677 (RefSeq)
cattle IL21 378475 (Entrez Gene)
Chr17 Q76LU5 (UniProt | EBI)
NM_198832 (RefSeq)
dog IL21 442935 (Entrez Gene)
Chr19 Q6L7I9 (UniProt | EBI)
NM_001003347 (RefSeq)
macaque, rhesus IL21 708125 (Entrez Gene)
Chr5 NP_001181171 (RefSeq)
NM_001194242 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory