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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLEKHA1 HGNC:14335 (HGNC)
59338 (Entrez Gene)
607772 (OMIM)
Chr10 q26.13 Chr10:122374578-122432355 (+)
Macular Degeneration, Age-Related, 1; ARMD1
Q9HB21 (UniProt | EBI)
NM_021622 (RefSeq)
mouse Plekha1 MGI:2442213 (MGI)
101476 (Entrez Gene)
Gene Tree
Chr7 73.19 cM Chr7:130865756-130913312 (+)
OTTMUSG00000029137 (VEGA)
OTTMUSP00000037143 (VEGA)
OTTMUST00000072263 (VEGA)
rat Plekha1 361659 (Entrez Gene)
Chr1 q37 NP_001073363 (RefSeq)
NM_001079894 (RefSeq)
chimpanzee PLEKHA1 450790 (Entrez Gene)
Chr10 XP_001159887 (RefSeq)
rhesus macaque PLEKHA1 705731 (Entrez Gene)
Chr9 XP_001103307 (RefSeq)
dog PLEKHA1 477851 (Entrez Gene)
Chr28 XP_005637863 (RefSeq)
chicken PLEKHA1 423940 (Entrez Gene)
Chr6 XP_421799 (RefSeq)
western clawed frog plekha1 549587 (Entrez Gene)
ChrUN NP_001016833 (RefSeq)
NM_001016833 (RefSeq)
zebrafish plekha1 406745 (Entrez Gene)
Chr17 NP_998601 (RefSeq)
NM_213436 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory