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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EPAS1 HGNC:3374 (HGNC)
2034 (Entrez Gene)
603349 (OMIM)
HGNC homology
Chr2 p21-p16 Chr2:46297402-46386703 (+)
Erythrocytosis, Familial, 4; ECYT4
Q99814 (UniProt | EBI)
NM_001430 (RefSeq)
mouse Epas1 MGI:109169 (MGI)
13819 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 56.9 cM Chr17:86753907-86833410 (+)
Respiratory Distress Syndrome in Premature Infants
ENSMUSG00000024140 (Ensembl Gene Model)
ENSMUSP00000024954 (Ensembl)
ENSMUST00000024954 (Ensembl)
rat Epas1 29452 (Entrez Gene)
Chr6 q12 Q9JHS1 (UniProt | EBI)
NM_023090 (RefSeq)
chimpanzee EPAS1 459204 (Entrez Gene)
Chr2A XP_001147219 (RefSeq)
rhesus macaque EPAS1 714641 (Entrez Gene)
Chr13 XP_014967768 (RefSeq)
cattle EPAS1 282711 (Entrez Gene)
Chr11 NP_777150 (RefSeq)
NM_174725 (RefSeq)
dog EPAS1 474578 (Entrez Gene)
Chr10 XP_005626137 (RefSeq)
chicken EPAS1 395596 (Entrez Gene)
Chr3 NP_990138 (RefSeq)
NM_204807 (RefSeq)
western clawed frog epas1 448117 (Entrez Gene)
ChrUN NP_001005647 (RefSeq)
NM_001005647 (RefSeq)
zebrafish epas1b 555192 (Entrez Gene)
Chr13 NP_001034895 (RefSeq)
NM_001039806 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory