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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EP300 HGNC:3373 (HGNC)
2033 (Entrez Gene)
602700 (OMIM)
HGNC homology
Chr22 q13.2 Chr22:41092610-41180077 (+)
Colorectal Cancer; CRC
Rubinstein-Taybi Syndrome 1; RSTS1
Rubinstein-Taybi Syndrome 2; RSTS2
Q09472 (UniProt | EBI)
NM_001429 (RefSeq)
mouse Ep300 MGI:1276116 (MGI)
328572 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 38.16 cM Chr15:81585351-81652072 (+)
Systemic Lupus Erythematosus; SLE
OTTMUSG00000048223 (VEGA)
OTTMUSP00000067505 (VEGA)
OTTMUST00000123794 (VEGA)
rat Ep300 170915 (Entrez Gene)
Chr7 q34 XP_001076610 (RefSeq)
NM_133403 (RefSeq)
chimpanzee EP300 458862 (Entrez Gene)
Chr22 NP_001231599 (RefSeq)
NM_001244670 (RefSeq)
rhesus macaque EP300 706258 (Entrez Gene)
Chr10 NP_001253415 (RefSeq)
NM_001266486 (RefSeq)
dog EP300 100684945 (Entrez Gene)
Chr10 XP_013972807 (RefSeq)
chicken EP300 418000 (Entrez Gene)
Chr1 XP_004937767 (RefSeq)
western clawed frog ep300 734023 (Entrez Gene)
ChrUN XP_002934771 (RefSeq)
zebrafish ep300a 559273 (Entrez Gene)
Chr12 XP_009304970 (RefSeq)
ep300b 565612 (Entrez Gene)
Chr3 XP_009297682 (RefSeq)
LOC100537254 100537254 (Entrez Gene)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory