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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
1094

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EP300 HGNC:3373 (HGNC)
2033 (Entrez Gene)
602700 (OMIM)
Chr22 q13.2 Chr22:41092302-41180083 (+)
GRCh38
Colorectal Cancer; CRC
Rubinstein-Taybi Syndrome 1; RSTS1
Rubinstein-Taybi Syndrome 2; RSTS2
Q09472 (UniProt | EBI)
NM_001429 (RefSeq)
mouse Ep300 MGI:1276116 (MGI)
328572 (Entrez Gene)
Gene Tree
VISTA-Point
Chr15 38.16 cM Chr15:81586214-81652077 (+)
GRCm38
Systemic Lupus Erythematosus; SLE
328572 (NCBI Gene Model)
B2RWS6 (UniProt | EBI)
NM_177821 (RefSeq)
rat Ep300 170915 (Entrez Gene)
Chr7 q34 XP_001076610 (RefSeq)
NM_133403 (RefSeq)
rhesus macaque EP300 706258 (Entrez Gene)
Chr10 NP_001253415 (RefSeq)
NM_001266486 (RefSeq)
cattle LOC784935 784935 (Entrez Gene)
Chr5
dog EP300 100684945 (Entrez Gene)
Chr10 XP_003431544 (RefSeq)
chicken EP300 418000 (Entrez Gene)
Chr1 XP_001233888 (RefSeq)
zebrafish ep300a 559273 (Entrez Gene)
Chr12 XP_001332718 (RefSeq)
ep300b 565612 (Entrez Gene)
Chr3 XP_003198146 (RefSeq)
LOC100537254 100537254 (Entrez Gene)
Chr12 XP_003199646 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory