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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLEKHG5 HGNC:29105 (HGNC)
57449 (Entrez Gene)
611101 (OMIM)
HGNC homology
Chr1 p36.31 Chr1:6466092-6520061 (-)
Charcot-Marie-Tooth Disease, Recessive Intermediate C; CMTRIC
Spinal Muscular Atrophy, Distal, Autosomal Recessive, 4; DSMA4
O94827 (UniProt | EBI)
NM_198681 (RefSeq)
mouse Plekhg5 MGI:2652860 (MGI)
269608 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 82.86 cM Chr4:152072498-152115400 (+)
OTTMUSG00000010225 (VEGA)
OTTMUSP00000010873 (VEGA)
OTTMUST00000023755 (VEGA)
rat Plekhg5 310999 (Entrez Gene)
Chr5 q36 Q6RFZ7 (UniProt | EBI)
NM_201272 (RefSeq)
rhesus macaque PLEKHG5 703518 (Entrez Gene)
Chr1 XP_002802190 (RefSeq)
cattle PLEKHG5 615910 (Entrez Gene)
Chr16 XP_010821412 (RefSeq)
NM_001193095 (RefSeq)
dog PLEKHG5 479590 (Entrez Gene)
Chr5 XP_005620516 (RefSeq)
chicken PLEKHG5 426013 (Entrez Gene)
Chr21 XP_004947394 (RefSeq)
western clawed frog plekhg5 100496612 (Entrez Gene)
ChrUN XP_012822815 (RefSeq)
zebrafish LOC796404 796404 (Entrez Gene)
Chr23 XP_005162505 (RefSeq)
plekhg5a 562861 (Entrez Gene)
Chr11 XP_009304323 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory