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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CYP11B2 HGNC:2592 (HGNC)
1585 (Entrez Gene)
124080 (OMIM)
Aldosterone synthase (MyGene.info)
HGNC homology
Chr8 q24.3 Chr8:142910559-142917843 (-)
P19099 (UniProt | EBI)
NM_000498 (RefSeq)
mouse Cyp11b1 MGI:88583 (MGI)
110115 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 34.29 cM Chr15:74834892-74841643 (-)
congenital adrenal hyperplasia
110115 (NCBI Gene Model)
NP_001028401 (RefSeq)
NM_001033229 (RefSeq)
rat Cyp11b3 353498 (Entrez Gene)
Chr7 q34 NP_861545 (RefSeq)
NM_181824 (RefSeq)
LOC100910462 100910462 (Entrez Gene)
Chr7 XP_008774718 (RefSeq)
cattle CYP11B1 282422 (Entrez Gene)
Chr14 P15150 (UniProt | EBI)
NM_174638 (RefSeq)
dog CYP11B2 482071 (Entrez Gene)
Chr13 XP_022282534 (RefSeq)
macaque, rhesus CYP11B2 695914 (Entrez Gene)
Chr8 NP_001180677 (RefSeq)
NM_001193748 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory