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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ECE1 HGNC:3146 (HGNC)
1889 (Entrez Gene)
600423 (OMIM)
Endothelin converting enzyme 1 (MyGene.info)
HGNC homology
Chr1 p36.12 Chr1:21217247-21345541 (-)
essential hypertension
P42892 (UniProt | EBI)
NM_001113347 (RefSeq)
mouse Ece1 MGI:1101357 (MGI)
230857 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 70.02 cM Chr4:137862237-137965229 (+)
double outlet right ventricle
OTTMUSG00000009809 (VEGA)
OTTMUSP00000010377 (VEGA)
OTTMUST00000022738 (VEGA)
rat Ece1 94204 (Entrez Gene)
Chr5 q36 P42893 (UniProt | EBI)
NM_053596 (RefSeq)
chimpanzee ECE1 456594 (Entrez Gene)
Chr1 XP_016811185 (RefSeq)
cattle ECE1 281133 (Entrez Gene)
Chr2 P42891 (UniProt | EBI)
NM_181009 (RefSeq)
dog ECE1 487388 (Entrez Gene)
Chr2 XP_005617901 (RefSeq)
chicken ECE1 395459 (Entrez Gene)
Chr21 NP_990048 (RefSeq)
NM_204717 (RefSeq)
zebrafish ece1 777750 (Entrez Gene)
Chr11 NP_001071260 (RefSeq)
NM_001077792 (RefSeq)
macaque, rhesus ECE1 706810 (Entrez Gene)
Chr1 XP_001099089 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory