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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PAPPA2 HGNC:14615 (HGNC)
60676 (Entrez Gene)
PAPPA2 (MyGene.info)
HGNC homology
Chr1 q25.2 Chr1:176463159-176845601 (+)
Q9BXP8 (UniProt | EBI)
NM_020318 (RefSeq)
mouse Pappa2 MGI:3051647 (MGI)
23850 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 68.49 cM Chr1:158711727-158960451 (-)
23850 (NCBI Gene Model)
NP_001078845 (RefSeq)
NM_001085376 (RefSeq)
rat Pappa2 680415 (Entrez Gene)
Chr13 q22 XP_017460131 (RefSeq)
chimpanzee PAPPA2 457543 (Entrez Gene)
Chr1 XP_009437092 (RefSeq)
cattle PAPPA2 538320 (Entrez Gene)
Chr16 XP_010811788 (RefSeq)
dog PAPPA2 480058 (Entrez Gene)
Chr7 XP_537179 (RefSeq)
chicken PAPPA2 429071 (Entrez Gene)
Chr8 XP_025008932 (RefSeq)
zebrafish pappa2 567038 (Entrez Gene)
Chr2 XP_695417 (RefSeq)
frog, western clawed pappa2 100491868 (Entrez Gene)
Chr4 XP_002931515 (RefSeq)
macaque, rhesus PAPPA2 709193 (Entrez Gene)
Chr1 XP_014979047 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory