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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SHANK2 HGNC:14295 (HGNC)
22941 (Entrez Gene)
603290 (OMIM)
SHANK2 (MyGene.info)
HGNC homology
Chr11 q13.3-q13.4 Chr11:70467856-71252724 (-)
autistic disorder
Q9UPX8 (UniProt | EBI)
NM_012309 (RefSeq)
mouse Shank2 MGI:2671987 (MGI)
210274 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 88.45 cM Chr7:144001928-144424494 (+)
autistic disorder
OTTMUSG00000016451 (VEGA)
OTTMUSP00000017693 (VEGA)
OTTMUST00000039639 (VEGA)
rat Shank2 171093 (Entrez Gene)
Chr1 q42 Q9QX74 (UniProt | EBI)
NM_133440 (RefSeq)
cattle SHANK2 618649 (Entrez Gene)
Chr29 XP_005197435 (RefSeq)
dog SHANK2 483677 (Entrez Gene)
Chr18 XP_022260831 (RefSeq)
chicken SHANK2 428858 (Entrez Gene)
Chr5 XP_015142375 (RefSeq)
zebrafish shank2 567595 (Entrez Gene)
Chr25 NP_001121819 (RefSeq)
NM_001128347 (RefSeq)
frog, western clawed shank2 100124731 (Entrez Gene)
Chr4 NP_001096183 (RefSeq)
NM_001102713 (RefSeq)
macaque, rhesus SHANK2 708192 (Entrez Gene)
Chr14 XP_014968917 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory