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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DKC1 HGNC:2890 (HGNC)
1736 (Entrez Gene)
300126 (OMIM)
Dyskerin (MyGene.info)
HGNC homology
ChrX q28 ChrX:154762742-154777689 (+)
X-linked dyskeratosis congenita
O60832 (UniProt | EBI)
NM_001288747 (RefSeq)
mouse Dkc1 MGI:1861727 (MGI)
245474 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 38.15 cM ChrX:75095854-75109777 (+)
dyskeratosis congenita
OTTMUSG00000020788 (VEGA)
OTTMUSP00000022726 (VEGA)
OTTMUST00000049145 (VEGA)
rat Dkc1 170944 (Entrez Gene)
ChrX P40615 (UniProt | EBI)
NM_133419 (RefSeq)
chimpanzee DKC1 465948 (Entrez Gene)
cattle DKC1 525619 (Entrez Gene)
ChrX NP_001098865 (RefSeq)
NM_001105395 (RefSeq)
dog DKC1 492263 (Entrez Gene)
ChrX XP_549382 (RefSeq)
chicken DKC1 422196 (Entrez Gene)
Chr4 Q5ZJH9 (UniProt | EBI)
NM_001031115 (RefSeq)
zebrafish dkc1 613144 (Entrez Gene)
Chr21 NP_001028279 (RefSeq)
NM_001033107 (RefSeq)
frog, western clawed dkc1 100145077 (Entrez Gene)
Chr8 XP_012824636 (RefSeq)
macaque, rhesus DKC1 702563 (Entrez Gene)
ChrX NP_001247923 (RefSeq)
NM_001260994 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory