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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DHCR7 HGNC:2860 (HGNC)
1717 (Entrez Gene)
602858 (OMIM)
7-Dehydrocholesterol reductase (MyGene.info)
HGNC homology
Chr11 q13.4 Chr11:71434411-71448431 (-)
Smith-Lemli-Opitz syndrome
Q9UBM7 (UniProt | EBI)
NM_001360 (RefSeq)
mouse Dhcr7 MGI:1298378 (MGI)
13360 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 88.33 cM Chr7:143823145-143848410 (+)
Smith-Lemli-Opitz syndrome
OTTMUSG00000025933 (VEGA)
OTTMUSP00000076463 (VEGA)
OTTMUST00000146974 (VEGA)
rat Dhcr7 64191 (Entrez Gene)
Chr1 q42 Q9Z2Z8 (UniProt | EBI)
NM_022389 (RefSeq)
chimpanzee DHCR7 451393 (Entrez Gene)
Chr11 XP_001174211 (RefSeq)
cattle DHCR7 514745 (Entrez Gene)
Chr29 Q5E9J5 (UniProt | EBI)
NM_001014927 (RefSeq)
dog DHCR7 483675 (Entrez Gene)
Chr18 XP_540796 (RefSeq)
chicken DHCR7 422982 (Entrez Gene)
Chr5 NP_001186419 (RefSeq)
NM_001199490 (RefSeq)
zebrafish dhcr7 378446 (Entrez Gene)
Chr2 Q7SXF1 (UniProt | EBI)
NM_201330 (RefSeq)
frog, western clawed dhcr7 394844 (Entrez Gene)
ChrUN Q6P4M0 (UniProt | EBI)
NM_203904 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory