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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1042

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DHCR7 HGNC:2860 (HGNC)
1717 (Entrez Gene)
602858 (OMIM)
Chr11 q13.4 Chr11:71434411-71448431 (-)
GRCh38
Smith-Lemli-Opitz Syndrome; SLOS
Q9UBM7 (UniProt | EBI)
NM_001360 (RefSeq)
mouse Dhcr7 MGI:1298378 (MGI)
13360 (Entrez Gene)
Gene Tree
VISTA-Point
Chr7 88.33 cM Chr7:143823145-143848410 (+)
GRCm38
Smith-Lemli-Opitz Syndrome; SLOS
OTTMUSG00000025933 (VEGA)
OTTMUSP00000031831 (VEGA)
OTTMUST00000064174 (VEGA)
rat Dhcr7 64191 (Entrez Gene)
Chr1 q41 Q9Z2Z8 (UniProt | EBI)
NM_022389 (RefSeq)
chimpanzee DHCR7 451393 (Entrez Gene)
Chr11 XP_001174206 (RefSeq)
cattle DHCR7 514745 (Entrez Gene)
Chr29 Q5E9J5 (UniProt | EBI)
NM_001014927 (RefSeq)
dog DHCR7 483675 (Entrez Gene)
Chr18 XP_540796 (RefSeq)
chicken DHCR7 422982 (Entrez Gene)
Chr5 NP_001186419 (RefSeq)
NM_001199490 (RefSeq)
western clawed frog dhcr7 394844 (Entrez Gene)
ChrUN Q6P4M0 (UniProt | EBI)
NM_203904 (RefSeq)
zebrafish dhcr7 378446 (Entrez Gene)
Chr2 Q7SXF1 (UniProt | EBI)
NM_201330 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory