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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TREM2 HGNC:17761 (HGNC)
54209 (Entrez Gene)
605086 (OMIM)
HGNC homology
Chr6 p21.1 Chr6:41158506-41163198 (-)
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy;
Q9NZC2 (UniProt | EBI)
NM_018965 (RefSeq)
mouse Trem2 MGI:1913150 (MGI)
83433 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 23.99 cM Chr17:48346401-48354147 (+)
OTTMUSG00000021045 (VEGA)
OTTMUSP00000023120 (VEGA)
OTTMUST00000049782 (VEGA)
chimpanzee TREM2 748470 (Entrez Gene)
Chr6 XP_009449501 (RefSeq)
rhesus macaque TREM2 719740 (Entrez Gene)
Chr4 XP_001117305 (RefSeq)
cattle TREM2 506467 (Entrez Gene)
Chr23 NP_001073048 (RefSeq)
NM_001079580 (RefSeq)
dog TREM2 608965 (Entrez Gene)
Chr12 XP_005627370 (RefSeq)
chicken TREM2 419920 (Entrez Gene)
Chr26 NP_001032921 (RefSeq)
NM_001037832 (RefSeq)
western clawed frog trem2 100126214 (Entrez Gene)
ChrUN NP_001103522 (RefSeq)
NM_001110052 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory