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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DISC1 HGNC:2888 (HGNC)
27185 (Entrez Gene)
605210 (OMIM)
DISC1 (MyGene.info)
HGNC homology
Chr1 q42.2 Chr1:231626815-232041272 (+)
schizophrenia 9
Q9NRI5 (UniProt | EBI)
NM_001164554 (RefSeq)
mouse Disc1 MGI:2447658 (MGI)
244667 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 73.26 cM Chr8:125054195-125261858 (+)
endogenous depression
OTTMUSG00000032471 (VEGA)
OTTMUSP00000043041 (VEGA)
OTTMUST00000080764 (VEGA)
rat Disc1 307940 (Entrez Gene)
Chr19 q12 Q810H6 (UniProt | EBI)
NM_175596 (RefSeq)
chimpanzee DISC1 742093 (Entrez Gene)
Chr1 XP_016796381 (RefSeq)
cattle DISC1 613555 (Entrez Gene)
Chr28 XP_024842704 (RefSeq)
dog DISC1 488970 (Entrez Gene)
Chr4 XP_022273123 (RefSeq)
chicken DISC1 100859633 (Entrez Gene)
Chr3 XP_025004695 (RefSeq)
macaque, rhesus DISC1 719086 (Entrez Gene)
Chr1 NP_001107827 (RefSeq)
NM_001114355 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory