Gene Expression Literature Summary
| Age | E12 | E13.5 | E14.5 | E15.5 | E16 | E16.5 | E17 | E18 | P |
| Western blot | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 9 |
| Dlk1 delta like non-canonical Notch ligand 1 (Synonyms: DlkI, FA1, Peg9, pG2, pref-1, SCP1, ZOG) | |
| Results | Reference |
| 2 | J:182286 Charalambous M, Ferron SR, da Rocha ST, Murray AJ, Rowland T, Ito M, Schuster-Gossler K, Hernandez A, Ferguson-Smith AC, Imprinted gene dosage is critical for the transition to independent life. Cell Metab. 2012 Feb 8;15(2):209-21 |
| 2 | J:258578 Cleaton MA, Dent CL, Howard M, Corish JA, Gutteridge I, Sovio U, Gaccioli F, Takahashi N, Bauer SR, Charnock-Jones DS, Powell TL, Smith GC, Ferguson-Smith AC, Charalambous M, Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction. Nat Genet. 2016 Dec;48(12):1473-1480 |
| 3 | J:146771 da Rocha ST, Charalambous M, Lin SP, Gutteridge I, Ito Y, Gray D, Dean W, Ferguson-Smith AC, Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting. PLoS Genet. 2009 Feb;5(2):e1000392 |
| 1 | J:361670 Defamie V, Aliar K, Sarkar S, Vyas F, Shetty R, Reddy Narala S, Fang H, Saw S, Tharmapalan P, Sanchez O, Knox JJ, Waterhouse PD, Khokha R, Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury. J Clin Invest. 2024 Dec 19;135(3) |
| 2 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
| 1 | J:227271 Gao YQ, Chen X, Wang P, Lu L, Zhao W, Chen C, Chen CP, Tao T, Sun J, Zheng YY, Du J, Li CJ, Gan ZJ, Gao X, Chen HQ, Zhu MS, Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13627-32 |
| 2 | J:306538 Ichinose M, Suzuki N, Wang T, Wright JA, Lannagan TRM, Vrbanac L, Kobayashi H, Gieniec KA, Ng JQ, Hayakawa Y, Garcia-Gallastegui P, Monsalve EM, Bauer SR, Laborda J, Garcia-Ramirez JJ, Ibarretxe G, Worthley DL, Woods SL, Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G506-G520 |
| 1* | J:81894 Lee K, Villena JA, Moon YS, Kim KH, Lee S, Kang C, Sul HS, Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1). J Clin Invest. 2003 Feb;111(4):453-61 |
| 1 | J:331835 Salazar-Petres E, Pereira-Carvalho D, Lopez-Tello J, Sferruzzi-Perri AN, Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice. Biol Reprod. 2022 Jun 13;106(6):1292-1311 |
| 1 | J:366212 Scagliotti V, Vignola ML, Willis T, Howard M, Marinelli E, Gaston-Massuet C, Andoniadou C, Charalambous M, Imprinted Dlk1 dosage as a size determinant of the mammalian pituitary gland. Elife. 2023 Aug 17;12 |
| 2* | J:208144 Shin S, Suh Y, Zerby HN, Lee K, Membrane-bound delta-like 1 homolog (Dlk1) promotes while soluble Dlk1 inhibits myogenesis in C2C12 cells. FEBS Lett. 2014 Apr 2;588(7):1100-8 |
| 1 | J:344643 Wang Q, Liu J, Zhong Y, Li D, Zhong Y, Ying H, Zhang T, A Fanca knockout mouse model reveals novel Fancd2 function. Biochem Biophys Res Commun. 2023 Dec 31;696:149454 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/19/2026 MGI 6.24 |
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