Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Axin2  axin 2   (Synonyms: Axil, Conductin)
Results	Reference
1	J:269508 Alonso-Martin S, Aurade F, Mademtzoglou D, Rochat A, Zammit PS, Relaix F, SOXF factors regulate murine satellite cell self-renewal and function through inhibition of beta-catenin activity. Elife. 2018 Jun 8;7:e26039
1	J:244906 Berthon A, Faucz FR, Espiard S, Drougat L, Bertherat J, Stratakis CA, Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function. Hum Mol Genet. 2017 Sep 15;26(18):3495-3507
1	J:193325 Boj SF, van Es JH, Huch M, Li VS, Jose A, Hatzis P, Mokry M, Haegebarth A, van den Born M, Chambon P, Voshol P, Dor Y, Cuppen E, Fillat C, Clevers H, Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
1	J:279588 Canal F, Charawi S, Grimber G, Houbron C, Drouet V, Colnot S, Terris B, Cavard C, Perret C, Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum. PLoS One. 2016;11(3):e0150997
1	J:198562 Cantu C, Valenta T, Hausmann G, Vilain N, Aguet M, Basler K, The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development. 2013 Jun;140(11):2377-86
1	J:239523 Chen CM, Orefice LL, Chiu SL, LeGates TA, Hattar S, Huganir RL, Zhao H, Xu B, Kuruvilla R, Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E619-E628
1	J:245870 Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J, YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme. Dev Cell. 2017 Oct 09;43(1):35-47.e4
1	J:309354 Cyge B, Voronina V, Hoque M, Kim EN, Hall J, Bailey-Lundberg JM, Pazour GJ, Crawford HC, Moon RT, Li FQ, Takemaru KI, Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis. Sci Rep. 2021 Aug 26;11(1):17220
1	J:243698 Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S, Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology. 2008 Jan;47(1):247-58
1	J:137914 Ellwanger K, Saito H, Clement-Lacroix P, Maltry N, Niedermeyer J, Lee WK, Baron R, Rawadi G, Westphal H, Niehrs C, Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol. 2008 Aug;28(15):4875-82
1	J:202907 Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W, Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9
1	J:235678 Grisanti L, Revenkova E, Gordon RE, Iomini C, Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway. Development. 2016 Jun 15;143(12):2160-71
1	J:221338 Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W, Guo F, The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/beta-catenin signaling. J Neurosci. 2015 Mar 25;35(12):5007-22
1*	J:184289 Hayano S, Kurosaka H, Yanagita T, Kalus I, Milz F, Ishihara Y, Islam MN, Kawanabe N, Saito M, Kamioka H, Adachi T, Dierks T, Yamashiro T, Roles of heparan sulfate sulfation in dentinogenesis. J Biol Chem. 2012 Apr 6;287(15):12217-29
1	J:176833 Kim TH, Shivdasani RA, Notch signaling in stomach epithelial stem cell homeostasis. J Exp Med. 2011 Apr 11;208(4):677-88
1	J:327072 Kim WK, Olson AW, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff R, You S, Sun Z, Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes. Nat Commun. 2022 Jul 28;13(1):4364
1	J:331419 Labbe P, Munoz Goyette V, Thorin-Trescases N, Villeneuve L, Desanlis I, Delwarde C, Shi YF, Martel C, Yu C, Alikashani A, Mamarbachi M, Lesage F, Mathieu S, Tardif JC, Mathieu P, Kmita M, Thorin E, Angiopoietin-like 2 is essential to aortic valve development in mice. Commun Biol. 2022 Nov 21;5(1):1277
1	J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475
1	J:171428 Li J, Huang X, Xu X, Mayo J, Bringas P Jr, Jiang R, Wang S, Chai Y, SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May;138(10):1977-89
1	J:337772 Liang X, Aranyi T, Zhou J, Guan Y, Hu H, Liu H, Susztak K, Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment. J Am Soc Nephrol. 2023 Apr 1;34(4):572-589
1	J:305040 Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Zhuang J, Wang Y, Wu X, Fan X, Pygo1 regulates pathological cardiac hypertrophy via a beta-catenin-dependent mechanism. Am J Physiol Heart Circ Physiol. 2021 Feb 26;320(4)
1	J:175083 Lorenz A, Deutschmann M, Ahlfeld J, Prix C, Koch A, Smits R, Fodde R, Kretzschmar HA, Schuller U, Severe alterations of cerebellar cortical development after constitutive activation of wnt signaling in granule neuron precursors. Mol Cell Biol. 2011 Aug;31(16):3326-38
1	J:166685 Love D, Li FQ, Burke MC, Cyge B, Ohmitsu M, Cabello J, Larson JE, Brody SL, Cohen JC, Takemaru K, Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/beta-catenin antagonist Chibby. PLoS One. 2010;5(10):e13600
1	J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819
1	J:334074 McCoy AM, Lakhdari O, Shome S, Caoili K, Hernandez GE, Aghaeepour N, Butcher LD, Fisch K, Prince LS, Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development. Development. 2023 Mar 1;150(5):dev200839
1*	J:192269 Mukhopadhyay A, Krishnaswami SR, Cowing-Zitron C, Hung NJ, Reilly-Rhoten H, Burns J, Yu BD, Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development. Dev Biol. 2013 Jan 15;373(2):373-82
1	J:309403 Nakagawa N, Xin C, Roach AM, Naiman N, Shankland SJ, Ligresti G, Ren S, Szak S, Gomez IG, Duffield JS, Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis. Kidney Int. 2015 Jun;87(6):1125-40
1	J:278935 Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF, MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. FASEB J. 2018 Jun 7;:fj201701274RR
1	J:226897 Parker A, Cross SH, Jackson IJ, Hardisty-Hughes R, Morse S, Nicholson G, Coghill E, Bowl MR, Brown SD, The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells. Dis Model Mech. 2015 Dec 1;8(12):1555-68
1	J:295059 Patel MM, Behar AR, Silasi R, Regmi G, Sansam CL, Keshari RS, Lupu F, Lupu C, Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function. J Am Heart Assoc. 2018 Nov 20;7(22):e010690
1	J:234178 Perdigoto CN, Dauber KL, Bar C, Tsai PC, Valdes VJ, Cohen I, Santoriello FJ, Zhao D, Zheng D, Hsu YC, Ezhkova E, Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016 Jul;12(7):e1006151
1	J:236636 Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS, The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size. Nat Cell Biol. 2016 May;18(5):467-79
1	J:242076 Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Konigshoff M, Hind M, Minelli C, Lloyd CM, Dean CH, Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech. 2017 Apr 01;10(4):409-423
1	J:259735 Rocha AS, Vidal V, Mertz M, Kendall TJ, Charlet A, Okamoto H, Schedl A, The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation. Cell Rep. 2015 Dec 1;13(9):1757-64
1	J:287213 Scortegagna M, Berthon A, Settas N, Giannakou A, Garcia G, Li JL, James B, Liddington RC, Vilches-Moure JG, Stratakis CA, Ronai ZA, The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion. JCI Insight. 2017 Dec 7;2(23)
1	J:279029 Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L, VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019 May 8;9(1):7079
1	J:124123 Strom A, Bonal C, Ashery-Padan R, Hashimoto N, Campos ML, Trumpp A, Noda T, Kido Y, Real FX, Thorel F, Herrera PL, Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas. Development. 2007 Aug;134(15):2719-25
1	J:335428 Sun XL, Chen ZH, Guo X, Wang J, Ge M, Wong SZH, Wang T, Li S, Yao M, Johnston LA, Wu QF, Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Dev Cell. 2023 May 8;58(9):744-759.e11
1*	J:194960 Tai G, Hohenstein P, Davies JA, FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique. Biol Open. 2013;2:416-423
1	J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539
1	J:147413 Voronina VA, Takemaru KI, Treuting P, Love D, Grubb BR, Hajjar AM, Adams A, Li FQ, Moon RT, Inactivation of Chibby affects function of motile airway cilia. J Cell Biol. 2009 Apr 20;185(2):225-33
1	J:305498 Wang H, Wang J, Zhao Y, Zhang X, Liu J, Zhang C, Haffty B, Verzi M, Zhang L, Gao N, Feng Z, Hu W, LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome. Cell Death Dis. 2020 Jul 27;11(7):588
1	J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21
1	J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404
1	J:212272 Wu J, Bao J, Kim M, Yuan S, Tang C, Zheng H, Mastick GS, Xu C, Yan W, Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2851-7
1*	J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
1	J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5
1	J:282241 Yang Y, Liu S, Lei Z, Chen G, Huang L, Yang F, Lei Y, Liu Y, Yang L, Liu W, Lai L, Guo J, Circular RNA profile in liver tissue of EpCAM knockout mice. Int J Mol Med. 2019 Sep;44(3):1063-1077
1	J:277277 Zieman AG, Poll BG, Ma J, Coulombe PA, Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. Hum Mol Genet. 2019 Jul 1;28(13):2255-2270