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Gene Expression Literature Summary
Assay
Age
RT-PCR
Postnatal

18 matching records from 18 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pten  phosphatase and tensin homolog   (Synonyms: 2310035O07Rik, A130070J02Rik, B430203M17Rik, MMAC1, TEP1)
Results  Reference
1J:334659 Chen H, Li J, Li H, Hu Y, Tevebaugh W, Yamamoto M, Que J, Chen X, Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus. PLoS One. 2012;7(5):e36504
1J:178952 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM, Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011 Nov 15;20(5):635-48
1J:207847 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain A, Noguchi C, Katagi A, Nishio M, Suzuki A, Lou X, Tokuda M, The expression of PTEN in the development of mouse cochlear lateral wall. Neuroscience. 2014 Jan 31;258:263-9
1J:166789 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M, Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010 Nov 10;170(4):1304-13
1J:190411 Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY, Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem. 2012 Sep 14;287(38):32172-9
1*J:286856 Funada K, Yoshizaki K, MIyazaki K, Han X, Yuta T, Tian T, Mizuta K, Fu Y, Iwamoto T, Yamada A, Takahashi I, Fukumoto S, microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development. Sci Rep. 2020 Mar 18;10(1):4918
1J:100493 Hamada K, Sasaki T, Koni PA, Natsui M, Kishimoto H, Sasaki J, Yajima N, Horie Y, Hasegawa G, Naito M, Miyazaki J, Suda T, Itoh H, Nakao K, Mak TW, Nakano T, Suzuki A, The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev. 2005 Sep 1;19(17):2054-65
1J:344559 Hughes CHK, Smith OE, Meinsohn MC, Brunelle M, Gevry N, Murphy BD, Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2220849120
1J:301834 Li G, Xu C, Lin X, Qu L, Xia D, Hongdu B, Xia Y, Wang X, Lou Y, He Q, Ma D, Chen Y, Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality. Cell Death Dis. 2017 May 25;8(5):e2811
1J:213579 Liao HF, Chen WS, Chen YH, Kao TH, Tseng YT, Lee CY, Chiu YC, Lee PL, Lin QJ, Ching YH, Hata K, Cheng WT, Tsai MH, Sasaki H, Ho HN, Wu SC, Huang YH, Yen P, Lin SP, DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development. 2014 Jun;141(12):2402-13
1J:161852 Libusova L, Stemmler MP, Hierholzer A, Schwarz H, Kemler R, N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development. 2010 Jul;137(14):2297-305
1J:144068 Nishino J, Kim I, Chada K, Morrison SJ, Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell. 2008 Oct 17;135(2):227-39
1*J:53065 Podsypanina K, Ellenson LH, Nemes A, Gu J, Tamura M, Yamada KM , Cordon-Cardo C , Catoretti G , Fisher PE , Parsons R, Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1563-8
1J:299569 Sanchez-Gurmaches J, Hung CM, Sparks CA, Tang Y, Li H, Guertin DA, PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors. Cell Metab. 2012 Sep 5;16(3):348-62
1J:197590 Tiozzo C, Danopoulos S, Lavarreda-Pearce M, Baptista S, Varimezova R, Al Alam D, Warburton D, Rehan V, De Langhe S, Di Cristofano A, Bellusci S, Minoo P, Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner. Endocr Relat Cancer. 2012 Apr;19(2):111-22
1J:167962 Tiozzo C, De Langhe S, Yu M, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson S, Borok Z, Bellusci S, Minoo P, Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. Am J Respir Crit Care Med. 2009 Oct 15;180(8):701-12
1J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20
1J:316591 Zou H, Ding Y, Shi W, Xu X, Gong A, Zhang Z, Liu J, MicroRNA-29c/PTEN pathway is involved in mice brain development and modulates neurite outgrowth in PC12 cells. Cell Mol Neurobiol. 2015 Apr;35(3):313-322

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory