Assay
Age
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RT-PCR
14.5 DPC
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Ins2 insulin II (Synonyms: Ins-2, InsII, Mody, Mody4) | |
Results | Reference |
1 | J:333987 Bohuslavova R, Fabriciova V, Lebron-Mora L, Malfatti J, Smolik O, Valihrach L, Benesova S, Zucha D, Berkova Z, Saudek F, Evans SM, Pavlinkova G, ISL1 controls pancreatic alpha cell fate and beta cell maturation. Cell Biosci. 2023 Mar 10;13(1):53 |
1 | J:309174 Bohuslavova R, Smolik O, Malfatti J, Berkova Z, Novakova Z, Saudek F, Pavlinkova G, NEUROD1 Is Required for the Early alpha and beta Endocrine Differentiation in the Pancreas. Int J Mol Sci. 2021 Jun 23;22(13) |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1* | J:3904 Deltour L, Leduque P, Blume N, Madsen O, Dubois P, Jami J, Bucchini D, Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo. Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):527-31 |
1* | J:24370 Deltour L, Montagutelli X, Guenet JL, Jami J, Paldi A, Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2. Dev Biol. 1995 Apr;168(2):686-8 |
1* | J:45695 Duvillie B, Bucchini D, Tang T, Jami J, Paldi A, Imprinting at the mouse Ins2 locus: evidence for cis- and trans-allelic interactions. Genomics. 1998 Jan 1;47(1):52-7 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1* | J:187631 Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E, Pancreas-enriched miRNA refines endocrine cell differentiation. Development. 2012 Aug;139(16):3021-31 |
1 | J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68 |
1 | J:290858 Marchant C, Anderson P, Schwarz Q, Wiszniak S, Vessel-derived angiocrine IGF1 promotes Meckel's cartilage proliferation to drive jaw growth during embryogenesis. Development. 2020 Jun 11;147(11):dev190488 |
1 | J:199085 Martinez-Campos E, Hernandez-Sanmiguel E, Lopez-Sanchez C, De Pablo F, Hernandez-Sanchez C, Alternative splicing variants of proinsulin mRNA and the effects of excess proinsulin on cardiac morphogenesis. FEBS Lett. 2013 Jul 11;587(14):2272-7 |
1* | J:42706 McGrath KE, Palis J, Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation. Mol Reprod Dev. 1997 Oct;48(2):145-53 |
1 | J:154407 Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F,Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA, Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes. 2009 Sep;58(9):2070-83 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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