Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gata4  GATA binding protein 4   (Synonyms: Gata-4)
Results	Reference
1	J:163855 Alder O, Lavial F, Helness A, Brookes E, Pinho S, Chandrashekran A, Arnaud P, Pombo A, O'Neill L, Azuara V, Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment. Development. 2010 Aug 1;137(15):2483-92
1*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
1	J:236524 Chatterjee S, Kapoor A, Akiyama JA, Auer DR, Lee D, Gabriel S, Berrios C, Pennacchio LA, Chakravarti A, Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease. Cell. 2016 Oct 6;167(2):355-368.e10
1	J:241786 Darwich R, Li W, Yamak A, Komati H, Andelfinger G, Sun K, Nemer M, KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5. Hum Mol Genet. 2017 Mar 01;26(5):942-954
1*	J:134429 Flagg AE, Earley JU, Svensson EC, FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing heart. Dev Biol. 2007 Apr 1;304(1):308-16
1	J:222397 Kulinski TM, Casari MR, Guenzl PM, Wenzel D, Andergassen D, Hladik A, Datlinger P, Farlik M, Theussl HC, Penninger JM, Knapp S, Bock C, Barlow DP, Hudson QJ, Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol. 2015 Jun 15;402(2):291-305
1*	J:175663 Laforest B, Andelfinger G, Nemer M, Loss of Gata5 in mice leads to bicuspid aortic valve. J Clin Invest. 2011 Jul 1;121(7):2876-87
1*	J:178176 Laforest B, Nemer M, GATA5 interacts with GATA4 and GATA6 in outflow tract development. Dev Biol. 2011 Oct 15;358(2):368-78
1*	J:297371 Lee CS, Cho HJ, Lee JW, Lee J, Kwon YW, Son T, Park H, Kim J, Kim HS, Identification of Latrophilin-2 as a Novel Cell-Surface Marker for the Cardiomyogenic Lineage and Its Functional Significance in Heart Development. Circulation. 2019 Jun 18;139(25):2910-2912
1	J:321017 Leung C, Engineer A, Kim MY, Lu X, Feng Q, Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects. J Cardiovasc Dev Dis. 2021 Mar 15;8(3)
1	J:222842 Liu Y, Lu X, Xiang FL, Poelmann RE, Gittenberger-de Groot AC, Robbins J, Feng Q, Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction. Eur Heart J. 2014 Apr;35(14):920-31
1	J:242127 Liu Z, Li W, Ma X, Ding N, Spallotta F, Southon E, Tessarollo L, Gaetano C, Mukouyama YS, Thiele CJ, Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. J Biol Chem. 2014 Oct 24;289(43):29801-16
1	J:317375 Ma CX, Song YL, Xiao L, Xue LX, Li WJ, Laforest B, Komati H, Wang WP, Jia ZQ, Zhou CY, Zou Y, Nemer M, Zhang SF, Bai X, Wu H, Zang MX, EGF is required for cardiac differentiation of P19CL6 cells through interaction with GATA-4 in a time- and dose-dependent manner. Cell Mol Life Sci. 2015 May;72(10):2005-22
1	J:138923 Manuylov NL, Manuylova E, Avdoshina V, Tevosian S, Serdin1/Lrrc10 is dispensable for mouse development. Genesis. 2008 Sep 9;46(9):441-446
1	J:143586 Manuylov NL, Smagulova FO, Leach L, Tevosian SG, Ovarian development in mice requires the GATA4-FOG2 transcription complex. Development. 2008 Nov;135(22):3731-43
1	J:172560 Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Rasanen J, Vainio SJ, Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Cardiovasc Res. 2010 Jan 1;85(1):100-9
1	J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50
1	J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82
1*	J:185738 Ounzain S, Kobayashi S, Peterson RE, He A, Motterle A, Samani NJ, Menick DR, Pu WT, Liang Q, Chong NW, Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Mol Cell Biol. 2012 May;32(10):1830-43
1	J:96456 Ritz-Laser B, Mamin A, Brun T, Avril I, Schwitzgebel VM, Philippe J, The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression. Mol Endocrinol. 2005 Mar;19(3):759-70
1	J:164834 Scott NJ, Ellmers LJ, Lainchbury JG, Maeda N, Smithies O, Richards AM, Cameron VA, Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development. Biochim Biophys Acta. 2009 Dec;1792(12):1175-84
1	J:155855 Singh MK, Li Y, Li S, Cobb RM, Zhou D, Lu MM, Epstein JA, Morrisey EE, Gruber PJ, Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice. J Biol Chem. 2010 Jan 15;285(3):1765-72
1	J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409
1	J:226104 Wang F, Wu Y, Quon MJ, Li X, Yang P, ASK1 mediates the teratogenicity of diabetes in the developing heart by inducing ER stress and inhibiting critical factors essential for cardiac development. Am J Physiol Endocrinol Metab. 2015 Sep 1;309(5):E487-99
1	J:217617 Xiong Y, Yang P, Proia RL, Hla T, Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development. J Clin Invest. 2014 Nov;124(11):4823-8
1*	J:229891 Xuan S, Sussel L, GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development. 2016 Mar 1;143(5):780-6