Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sry  sex determining region of Chr Y   (Synonyms: Tdf, Tdy)
Results	Reference
1	J:98922 Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM, Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul;132(13):3045-54
1*	J:93500 Bouma GJ, Hart GT, Washburn LL, Recknagel AK, Eicher EM, Using real time RT-PCR analysis to determine multiple gene expression patterns during XX and XY mouse fetal gonad development. Gene Expr Patterns. 2004 Nov;5(1):141-9
1*	J:183829 Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH, Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569
1	J:191095 Gierl MS, Gruhn WH, von Seggern A, Maltry N, Niehrs C, GADD45G functions in male sex determination by promoting p38 signaling and Sry expression. Dev Cell. 2012 Nov 13;23(5):1032-42
1	J:267191 Gregoire EP, Stevant I, Chassot AA, Martin L, Lachambre S, Mondin M, de Rooij DG, Nef S, Chaboissier MC, NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis. Mol Cell Endocrinol. 2018 Dec 15;478:17-31
1	J:71149 Hammes A, Guo JK, Lutsch G, Leheste JR, Landrock D, Ziegler U, Gubler MC, Schedl A, Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell. 2001 Aug 10;106(3):319-29
1*	J:27741 Jeske YW, Bowles J, Greenfield A, Koopman P, Expression of a linear Sry transcript in the mouse genital ridge. Nat Genet. 1995 Aug;10(4):480-2
1*	J:33399 Jeske YW, Mishina Y, Cohen DR, Behringer RR, Koopman P, Analysis of the role of Amh and Fra1 in the Sry regulatory pathway. Mol Reprod Dev. 1996 Jun;44(2):153-8
1	J:96334 Kidokoro T, Matoba S, Hiramatsu R, Fujisawa M, Kanai-Azuma M, Taya C, Kurohmaru M, Kawakami H, Hayashi Y, Kanai Y, Yonekawa H, Influence on spatiotemporal patterns of a male-specific Sox9 activation by ectopic Sry expression during early phases of testis differentiation in mice. Dev Biol. 2005 Feb 15;278(2):511-25
1	J:200895 Kuroki S, Matoba S, Akiyoshi M, Matsumura Y, Miyachi H, Mise N, Abe K, Ogura A, Wilhelm D, Koopman P, Nozaki M, Kanai Y, Shinkai Y, Tachibana M, Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a. Science. 2013 Sep 6;341(6150):1106-9
1*	J:69946 Lee CH, Taketo T, Low levels of Sry transcripts cannot be the sole cause of B6-Y(TIR) sex reversal. Genesis. 2001 May;30(1):7-11
1	J:199294 Munger SC, Natarajan A, Looger LL, Ohler U, Capel B, Fine time course expression analysis identifies cascades of activation and repression and maps a putative regulator of Mammalian sex determination. PLoS Genet. 2013 Jul;9(7):e1003630
1*	J:92839 Nordqvist K, Tohonen V, An mRNA differential display strategy for cloning genes expressed during mouse gonad development. Int J Dev Biol. 1997 Aug;41(4):627-38
1*	J:284860 Okashita N, Kuroki S, Maeda R, Tachibana M, TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. Sci Rep. 2019 Sep 17;9(1):13462
1	J:172637 Park S, Zeidan K, Shin JS, Taketo T, SRY upregulation of SOX9 is inefficient and delayed, allowing ovarian differentiation, in the B6.Y(TIR) gonad. Differentiation. 2011 Jul;82(1):18-27
1	J:273632 Planells B, Gomez-Redondo I, Pericuesta E, Lonergan P, Gutierrez-Adan A, Differential isoform expression and alternative splicing in sex determination in mice. BMC Genomics. 2019 Mar 12;20(1):202
1	J:215196 Quinn A, Kashimada K, Davidson TL, Ng ET, Chawengsaksophak K, Bowles J, Koopman P, A site-specific, single-copy transgenesis strategy to identify 5' regulatory sequences of the mouse testis-determining gene Sry. PLoS One. 2014;9(4):e94813
1*	J:51224 Tohonen V, Osterlund C, Nordqvist K, Testatin: a cystatin-related gene expressed during early testis development. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14208-13
1	J:191096 Warr N, Carre GA, Siggers P, Faleato JV, Brixey R, Pope M, Bogani D, Childers M, Wells S, Scudamore CL, Tedesco M, del Barco Barrantes I, Nebreda AR, Trainor PA, Greenfield A, Gadd45gamma and Map3k4 interactions regulate mouse testis determination via p38 MAPK-mediated control of Sry expression. Dev Cell. 2012 Nov 13;23(5):1020-31
1	J:210362 Warr N, Siggers P, Carre GA, Bogani D, Brixey R, Akiyoshi M, Tachibana M, Teboul L, Wells S, Sanderson J, Greenfield A, Transgenic expression of Map3k4 rescues T-associated sex reversal (Tas) in mice. Hum Mol Genet. 2014 Jun 1;23(11):3035-44
1*	J:103443 Wilhelm D, Martinson F, Bradford S, Wilson MJ, Combes AN, Beverdam A, Bowles J, Mizusaki H, Koopman P, Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol. 2005 Nov 1;287(1):111-24