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Gene Expression Literature Summary
Assay
Age
RT-PCR
11.5 DPC

10 matching records from 10 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dlx5  distal-less homeobox 5  
Results  Reference
1*J:185735 Birnbaum RY, Clowney EJ, Agamy O, Kim MJ, Zhao J, Yamanaka T, Pappalardo Z, Clarke SL, Wenger AM, Nguyen L, Gurrieri F, Everman DB, Schwartz CE, Birk OS, Bejerano G, Lomvardas S, Ahituv N, Coding exons function as tissue-specific enhancers of nearby genes. Genome Res. 2012 Jun;22(6):1059-68
1*J:188336 Birnbaum RY, Everman DB, Murphy KK, Gurrieri F, Schwartz CE, Ahituv N, Functional characterization of tissue-specific enhancers in the DLX5/6 locus. Hum Mol Genet. 2012 Nov 15;21(22):4930-8
1*J:267540 Cesario JM, Landin Malt A, Chung JU, Khairallah MP, Dasgupta K, Asam K, Deacon LJ, Choi V, Almaidhan AA, Darwiche NA, Kim J, Johnson RL, Jeong J, Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria. Dev Biol. 2018 Nov 15;443(2):103-116
1J:229484 Conte D, Garaffo G, Lo Iacono N, Mantero S, Piccolo S, Cordenonsi M, Perez-Morga D, Orecchia V, Poli V, Merlo GR, The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand. Hum Mol Genet. 2016 Feb 15;25(4):740-54
1J:312374 Fazel Darbandi S, Esau C, Lesage-Pelletier C, Monis S, Poitras L, Yu M, Perin S, Hatch G, Ekker M, Increased Sociability in Mice Lacking Intergenic Dlx Enhancers. Front Neurosci. 2021;15:718948
1J:327183 Gu R, Zhang S, Saha SK, Ji Y, Reynolds K, McMahon M, Sun B, Islam M, Trainor PA, Chen Y, Xu Y, Chai Y, Burkart-Waco D, Zhou CJ, Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts. Development. 2022 Jul 15;149(14):dev200533
1J:245137 Kawata M, Taniguchi Y, Mori D, Yano F, Ohba S, Chung UI, Shimogori T, Mills AA, Tanaka S, Saito T, Different regulation of limb development by p63 transcript variants. PLoS One. 2017;12(3):e0174122
1J:135784 Lo Iacono N, Mantero S, Chiarelli A, Garcia E, Mills AA, Morasso MI, Costanzo A, Levi G, Guerrini L, Merlo GR, Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development. 2008 Apr;135(7):1377-88
1*J:293200 Vanyai HK, Garnham A, May RE, McRae HM, Collin C, Wilcox S, Smyth GK, Thomas T, Voss AK, MOZ directs the distal-less homeobox gene expression program during craniofacial development. Development. 2019 Jul 24;146(14):dev175042
1*J:50563 Yang L, Zhang H, Hu G, Wang H, Abate-Shen C, Shen MM, An early phase of embryonic Dlx5 expression defines the rostral boundary of the neural plate. J Neurosci. 1998 Oct 15;18(20):8322-30

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory