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Gene Expression Literature Summary
Symbol
Name
ID
Mark2
MAP/microtubule affinity regulating kinase 2
MGI:99638

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E3 E4 E14 E16 E16.5 E18 E18.5 P
Immunohistochemistry (section) 1
In situ RNA (section) 1 1
Immunohistochemistry (whole mount) 1 1 1 1
Western blot 1 1 1 1 2
RT-PCR 1 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mark2  MAP/microtubule affinity regulating kinase 2   (Synonyms: Emk, Par-1)
Results  Reference
1J:161201 Gao N, Kaestner KH, Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
1J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8
1J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25
12*J:100660 Moore CA, Zernicka-Goetz M, PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles. Reproduction. 2005 Sep;130(3):311-20
2J:136389 Sapir T, Sapoznik S, Levy T, Finkelshtein D, Shmueli A, Timm T, Mandelkow EM, Reiner O, Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration. J Neurosci. 2008 May 28;28(22):5710-20
1J:183948 Tao H, Inoue K, Kiyonari H, Bassuk AG, Axelrod JD, Sasaki H, Aizawa S, Ueno N, Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev Biol. 2012 Apr 15;364(2):138-48
1*J:121102 Uboha NV, Flajolet M, Nairn AC, Picciotto MR, A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth. J Neurosci. 2007 Apr 18;27(16):4413-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory