Gene Expression Literature Summary

• Symbol: Vil1
• Name: villin 1
• ID: MGI:98930

47 matching records from 47 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5	E6	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	P
Immunohistochemistry (section)	1	1	1	2	1	3	2	1	1	2	1	1	1	1		1	1		1	3		3	1		1	8		14
In situ RNA (section)				1										1		1		2		2		1		1				3
In situ RNA (whole mount)				1										1						1
In situ reporter (knock in)			1	1	1	1	1	1		1		1		1		1	1	1		1		1		1		1		1
Western blot										1																1		1
RT-PCR				1					1						1	1		3	2		1	2	1			1	1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vil1  villin 1   (Synonyms: Villin)
Results	Reference
2	J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39
1*	J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90
1	J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31
18	J:76398 Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL, Villin: A marker for development of the epithelial pyloric border. Dev Dyn. 2002 May;224(1):90-102
1	J:145166 Cervantes S, Yamaguchi TP, Hebrok M, Wnt5a is essential for intestinal elongation in mice. Dev Biol. 2009 Feb 15;326(2):285-94
1*	J:284137 Chen L, Toke NH, Luo S, Vasoya RP, Aita R, Parthasarathy A, Tsai YH, Spence JR, Verzi MP, HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine. Development. 2019 Aug 6;146(19):dev179432
1	J:119657 Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH, Kushida M, Qiu W, Mills AA, Kim PC, DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development. 2006 Dec;133(23):4783-92
1	J:291945 De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, Mechine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E, Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. 2017 Oct;66(10):1748-1760
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:314694 Douchi D, Yamamura A, Matsuo J, Melissa Lim YH, Nuttonmanit N, Shimura M, Suda K, Chen S, Pang S, Kohu K, Abe T, Shioi G, Kim G, Shabbir A, Srivastava S, Unno M, Bok-Yan So J, Teh M, Yeoh KG, Huey Chuang LS, Ito Y, Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus. Gastroenterology. 2021 Dec;161(6):1907-1923.e26
2	J:146503 Downs KM, Inman KE, Jin DX, Enders AC, The Allantoic Core Domain: New insights into development of the murine allantois and its relation to the primitive streak. Dev Dyn. 2009 Mar;238(3):532-53
2	J:262635 Drake KA, Adam M, Mahoney R, Potter SS, Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney. Sci Rep. 2018 Apr 20;8(1):6306
1	J:241179 Duquesnes N, Callot C, Jeannot P, Daburon V, Nakayama KI, Manenti S, Davy A, Besson A, p57(Kip2) knock-in mouse reveals CDK-independent contribution in the development of Beckwith-Wiedemann syndrome. J Pathol. 2016 Jul;239(3):250-61
1	J:115635 Elling U, Klasen C, Eisenberger T, Anlag K, Treier M, Murine inner cell mass-derived lineages depend on Sall4 function. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16319-24
1	J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173
10*	J:289366 Ezzell RM, Chafel MM, Matsudaira PT, Differential localization of villin and fimbrin during development of the mouse visceral endoderm and intestinal epithelium. Development. 1989 Jun;106(2):407-19
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1	J:161201 Gao N, Kaestner KH, Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
1*	J:150374 Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G, LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol. 2009 Jul 1;331(1):58-67
2	J:87048 Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA, Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Development. 2004 Jan;131(1):165-79
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:263185 Huang M, He H, Belenkaya T, Lin X, Multiple roles of epithelial heparan sulfate in stomach morphogenesis. J Cell Sci. 2018 May 29;131(10):jcs210781
1	J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64
1	J:189974 Kiefer SM, Robbins L, Rauchman M, Conditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney function. PLoS One. 2012;7(8):e43098
1*	J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90
1*	J:156319 Kwon MC, Koo BK, Kim YY, Lee SH, Kim NS, Kim JH, Kong YY, Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal development. J Biol Chem. 2009 Nov 27;284(48):33634-41
6	J:17719 Landry C, Huet C, Mangeat P, Sahuquet A, Louvard D, Crine P, Comparative analysis of neutral endopeptidase (NEP) and villin gene expression during mouse embryogenesis and enterocyte maturation. Differentiation. 1994 Apr;56(1-2):55-65
1*	J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217
1	J:161852 Libusova L, Stemmler MP, Hierholzer A, Schwarz H, Kemler R, N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development. 2010 Jul;137(14):2297-305
1	J:164479 Lozovatsky L, Abayasekara N, Piawah S, Walther Z, CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity. Mol Biol Cell. 2009 Nov;20(21):4489-99
4	J:194050 Massa F, Garbay S, Bouvier R, Sugitani Y, Noda T, Gubler MC, Heidet L, Pontoglio M, Fischer E, Hepatocyte nuclear factor 1beta controls nephron tubular development. Development. 2013 Feb;140(4):886-96
14	J:1712 Maunoury R, Robine S, Pringault E, Leonard N, Gaillard JA, Louvard D, Developmental regulation of villin gene expression in the epithelial cell lineages of mouse digestive and urogenital tracts. Development. 1992 Jul;115(3):717-28
1*	J:173765 Mustata RC, Van Loy T, Lefort A, Libert F, Strollo S, Vassart G, Garcia MI, Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo. EMBO Rep. 2011 Jun;12(6):558-64
1	J:186888 Nagalakshmi VK, Ren Q, Pugh MM, Valerius MT, McMahon AP, Yu J, Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int. 2011 Feb;79(3):317-30
1	J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498
1*	J:209852 Prandi S, Bromke M, Hubner S, Voigt A, Boehm U, Meyerhof W, Behrens M, A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131. PLoS One. 2013;8(12):e82820
1	J:261444 Pyrski M, Eckstein E, Schmid A, Bufe B, Weiss J, Chubanov V, Boehm U, Zufall F, Trpm5 expression in the olfactory epithelium. Mol Cell Neurosci. 2017 Apr;80:75-88
4	J:255143 Rasouly HM, Kumar S, Chan S, Pisarek-Horowitz A, Sharma R, Xi QJ, Nishizaki Y, Higashi Y, Salant DJ, Maas RL, Lu W, Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int. 2016 Dec;90(6):1262-1273
1	J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204
1	J:298037 Shi W, Kaneiwa T, Cydzik M, Gariepy J, Filmus J, Glypican-6 stimulates intestinal elongation by simultaneously regulating Hedgehog and non-canonical Wnt signaling. Matrix Biol. 2020 Jun;88:19-32
1	J:306135 Shimizu R, Ishihara K, Kawashita E, Sago H, Yamakawa K, Mizutani KI, Akiba S, Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models. Biochem Biophys Res Commun. 2021 Jan 8;535:87-92
1	J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74
3*	J:89931 Tou L, Liu Q, Shivdasani RA, Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol. 2004 Apr;24(8):3132-9
1*	J:133949 Valerius MT, McMahon AP, Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation. Gene Expr Patterns. 2008 May;8(5):297-306
1	J:173368 Wang X, Ouyang H, Yamamoto Y, Kumar PA, Wei TS, Dagher R, Vincent M, Lu X, Bellizzi AM, Ho KY, Crum CP, Xian W, McKeon F, Residual Embryonic Cells as Precursors of a Barrett's-like Metaplasia. Cell. 2011 Jun 24;145(7):1023-35
1	J:226215 Yamaguchi T, Yamashita J, Ohmoto M, Aoude I, Ogura T, Luo W, Bachmanov AA, Lin W, Matsumoto I, Hirota J, Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium. BMC Neurosci. 2014;15:13
1	J:243534 Zhang Y, Xie S, Zhou Y, Xie Y, Liu P, Sun M, Xiao H, Jin Y, Sun X, Chen Z, Huang Q, Chen S, H3K36 histone methyltransferase Setd2 is required for murine embryonic stem cell differentiation toward endoderm. Cell Rep. 2014 Sep 25;8(6):1989-2002