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Gene Expression Literature Summary
Symbol
Name
ID
Trh
thyrotropin releasing hormone
MGI:98823

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E5.5 E6.5 E7 E7.5 E8 E8.5 E9 E9.5 E10.5 E11.5 E12.5 E13.5 E14.5 E15 E15.5 E18.5 E A
In situ RNA (section) 1 1 1 1 1 1 1 1 3 1 4 1 5 2 6
In situ RNA (whole mount) 1 1 1 2 4 4 2 1 1 1 1
Northern blot 1
Western blot 1 1
RT-PCR 1 1 2 1 4
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Trh  thyrotropin releasing hormone  
Results  Reference
3J:58466 Acampora D, Postiglione MP, Avantaggiato V, Di Bonito M, Vaccarino FM, Michaud J, Simeone A, Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes Dev. 1999 Nov 1;13(21):2787-800
1J:81143 Backman M, Machon O, Van Den Bout CJ, Krauss S, Targeted disruption of mouse Dach1 results in postnatal lethality. Dev Dyn. 2003 Jan;226(1):139-44
3*J:119269 Caqueret A, Boucher F, Michaud JL, Laminar organization of the early developing anterior hypothalamus. Dev Biol. 2006 Oct 1;298(1):95-106
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:161632 Garcia-Moreno F, Pedraza M, Di Giovannantonio LG, Di Salvio M, Lopez-Mascaraque L, Simeone A, De Carlos JA, A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nat Neurosci. 2010 Jun;13(6):680-9
3J:89548 Goshu E, Jin H, Lovejoy J, Marion JF, Michaud JL, Fan CM, Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus. Mol Endocrinol. 2004 May;18(5):1251-62
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1*J:105434 Hernandez A, Martinez ME, Fiering S, Galton VA, St Germain D, Type 3 deiodinase is critical for the maturation and function of the thyroid axis. J Clin Invest. 2006 Feb;116(2):476-84
5*J:125749 Hou J, Charters AM, Lee SC, Zhao Y, Wu MK, Jones SJ, Marra MA, Hoodless PA, A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE). BMC Dev Biol. 2007;7:92
7J:112633 Jukkola T, Lahti L, Naserke T, Wurst W, Partanen J, FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Dev Biol. 2006 Sep 1;297(1):141-57
1J:69874 Keith B, Adelman DM, Simon MC, Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6692-7
15*J:125491 McKnight KD, Hou J, Hoodless PA, Dynamic expression of Thyrotropin-releasing hormone in the mouse definitive endoderm. Dev Dyn. 2007 Oct;236(10):2909-17
3J:157265 McKnight KD, Hou J, Hoodless PA, Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm. Dev Biol. 2010 Jan 15;337(2):471-81
1J:60430 Michaud JL, DeRossi C, May NR, Holdener BC, Fan CM, ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus. Mech Dev. 2000 Feb;90(2):253-61
1J:50772 Michaud JL, Rosenquist T, May NR, Fan CM, Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. Genes Dev. 1998 Oct 15;12(20):3264-75
4J:179470 Perez-Monter C, Martinez-Armenta M, Miquelajauregui A, Furlan-Magaril M, Varela-Echavarria A, Recillas-Targa F, May V, Charli JL, Perez-Martinez L, The Kruppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development. Mol Cell Endocrinol. 2011 Feb 20;333(2):127-33
1J:155932 Rose MF, Ahmad KA, Thaller C, Zoghbi HY, Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22462-7
1J:30430 Schonemann MD, Ryan AK, McEvilly RJ, O'Connell SM, Arias CA, Kalla KA, Li P, Sawchenko PE, Rosenfeld MG, Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev. 1995 Dec 15;9(24):3122-35
1J:190867 Sun Y, Bak B, Schoenmakers N, van Trotsenburg AS, Oostdijk W, Voshol P, Cambridge E, White JK, le Tissier P, Gharavy SN, Martinez-Barbera JP, Stokvis-Brantsma WH, Vulsma T, Kempers MJ, Persani L, Campi I, Bonomi M, Beck-Peccoz P, Zhu H, Davis TM, Hokken-Koelega AC, Del Blanco DG, Rangasami JJ, Ruivenkamp CA, Laros JF, Kriek M, Kant SG, Bosch CA, Biermasz NR, Appelman-Dijkstra NM, Corssmit EP, Hovens GC, Pereira AM, den Dunnen JT, Wade MG, Breuning MH, Hennekam RC, Chatterjee K, Dattani MT, Wit JM, Bernard, Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement. Nat Genet. 2012 Dec;44(12):1375-81
2*J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
1J:171102 Tomas-Roca L, Perez-Aytes A, Puelles L, Marin F, In silico identification of new candidate genes for hereditary congenital facial paresis. Int J Dev Neurosci. 2011 Jun;29(4):451-60
4*J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67
2J:65759 Wang W, Lufkin T, The murine otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol. 2000 Nov 15;227(2):432-49

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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory