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Gene Expression Literature Summary
Symbol
Name
ID
Thrb
thyroid hormone receptor beta
MGI:98743

41 matching records from 41 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E A
In situ protein (section) 1 1 1 1 2 5 3 1 3 1 3 1 6
In situ RNA (section) 1 4 2 1 1 2 7
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1 1 1
Northern blot 1 1 1 1 1 1 1 4
Western blot 1 2 1 3
RT-PCR 1 1 1 3 1 1 3 2 2 3 2 3 1 1 1 13
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Thrb  thyroid hormone receptor beta   (Synonyms: c-erbAbeta, Nr1a2, T3R[b], T3Rbeta, Thrb1, Thrb2, TR beta)
Results  Reference
6*J:121116 Applebury ML, Farhangfar F, Glosmann M, Hashimoto K, Kage K, Robbins JT, Shibusawa N, Wondisford FE, Zhang H, Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis. Dev Dyn. 2007 May;236(5):1203-12
2J:156665 Brzezinski JA 4th, Lamba DA, Reh TA, Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development. Development. 2010 Feb;137(4):619-29
1J:159104 Cai Z, Feng GS, Zhang X, Temporal requirement of the protein TyrosinePhosphatase Shp2 in establishing the neuronal fatein early retinal development. J Neurosci. 2010 Mar 17;30(11):4110-9
3*J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98
2*J:51607 Causak RA, Zgleszewski SE, Zhang L, Cilley RE, Krummel TM, Chinoy MR, Differential gene expression at gestational days 14 and 16 in normal and nitrogen-induced hypoplastic murine fetal lungs with coexistent diaphragmatic hernia. Pediatr Pulmonol. 1998 Nov;26(5):301-11
4J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
2*J:107820 Corbo JC, Cepko CL, A Hybrid Photoreceptor Expressing Both Rod and Cone Genes in a Mouse Model of Enhanced S-Cone Syndrome. PLoS Genet. 2005 Aug 5;1(2):e11
2J:182543 Cordas EA, Ng L, Hernandez A, Kaneshige M, Cheng SY, Forrest D, Thyroid hormone receptors control developmental maturation of the middle ear and the size of the ossicular bones. Endocrinology. 2012 Mar;153(3):1548-60
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:143073 Fujieda H, Bremner R, Mears AJ, Sasaki H, Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development. J Neurochem. 2009 Jan;108(1):91-101
1J:210692 Hagglund AC, Berghard A, Carlsson L, Canonical Wnt/beta-catenin signalling is essential for optic cup formation. PLoS One. 2013;8(12):e81158
2J:153683 Jia L, Oh EC, Ng L, Srinivas M, Brooks M, Swaroop A, Forrest D, Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17534-9
4J:120914 Jones I, Ng L, Liu H, Forrest D, An intron control region differentially regulates expression of thyroid hormone receptor beta2 in the cochlea, pituitary, and cone photoreceptors. Mol Endocrinol. 2007 May;21(5):1108-19
1J:143205 Kanadia RN, Clark VE, Punzo C, Trimarchi JM, Cepko CL, Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons. Development. 2008 Dec;135(23):3923-33
1J:160529 Katoh K, Omori Y, Onishi A, Sato S, Kondo M, Furukawa T, Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J Neurosci. 2010 May 12;30(19):6515-26
1J:193195 Katoh K, Yamazaki R, Onishi A, Sanuki R, Furukawa T, G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells. J Neurosci. 2012 Dec 5;32(49):17658-70
1J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302
3J:131378 Liu H, Etter P, Hayes S, Jones I, Nelson B, Hartman B, Forrest D, Reh TA, NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina. J Neurosci. 2008 Jan 16;28(3):749-56
1J:158094 Lu A, Ng L, Ma M, Kefas B, Davies TF, Hernandez A, Chan CC, Forrest D, Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice. Endocrinology. 2009 Mar;150(3):1536-44
1J:181993 Luo H, Jin K, Xie Z, Qiu F, Li S, Zou M, Cai L, Hozumi K, Shima DT, Xiang M, Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):E553-62
2*J:91511 Mai W, Janier MF, Allioli N, Quignodon L, Chuzel T, Flamant F, Samarut J, Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10332-7
5*J:39152 Nagasawa T, Suzuki S, Takeda T, DeGroot LJ, Thyroid hormone receptor beta 1 expression in developing mouse limbs and face. Endocrinology. 1997 Mar;138(3):1276-81
3J:113328 Nakamura K, Itoh K, Yaoi T, Fujiwara Y, Sugimoto T, Fushiki S, Murine neocortical histogenesis is perturbed by prenatal exposure to low doses of bisphenol A. J Neurosci Res. 2006 Aug 10;84(6):1197-1205
1J:151815 Ng L, Hernandez A, He W, Ren T, Srinivas M, Ma M, Galton VA, St Germain DL, Forrest D, A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology. 2009 Apr;150(4):1952-60
4J:66737 Ng L, Hurley JB, Dierks B, Srinivas M, Salto C, Vennstrom B, Reh TA, Forrest D, A thyroid hormone receptor that is required for the development of green cone photoreceptors. Nat Genet. 2001 Jan;27(1):94-8
4J:174592 Ng L, Lu A, Swaroop A, Sharlin DS, Swaroop A, Forrest D, Two transcription factors can direct three photoreceptor outcomes from rod precursor cells in mouse retinal development. J Neurosci. 2011 Aug 3;31(31):11118-25
1J:159022 Ng L, Lyubarsky A, Nikonov SS, Ma M, Srinivas M, Kefas B, St Germain DL, Hernandez A, Pugh EN Jr, Forrest D, Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. J Neurosci. 2010 Mar 3;30(9):3347-57
10J:155780 Ng L, Ma M, Curran T, Forrest D, Developmental expression of thyroid hormone receptor beta2 protein in cone photoreceptors in the mouse. Neuroreport. 2009 Apr 22;20(6):627-31
2*J:170404 Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Watanabe S, Takaya T, Tamaki Y, Takanabe-Mori R, Wada H, Hasegawa K, Iwanaga Y, Kawamura T, Kita T, Kimura T, MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes. Mol Cell Biol. 2011 Feb;31(4):744-55
1J:84310 O'Shea PJ, Harvey CB, Suzuki H, Kaneshige M, Kaneshige K, Cheng SY, Williams GR, A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. Mol Endocrinol. 2003 Jul;17(7):1410-24
1J:142509 Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R, Dual requirement for Pax6 in retinal progenitor cells. Development. 2008 Dec;135(24):4037-47
4J:178114 Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li HR, Downes M, Yu RT, Powell HC, Lingrel JB, Evans RM, Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nat Med. 2011;17(11):1466-72
1J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403
2J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77
4J:103712 Roberts MR, Hendrickson A, McGuire CR, Reh TA, Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina. Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2897-904
4*J:179032 Sharlin DS, Visser TJ, Forrest D, Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea. Endocrinology. 2011 Dec;152(12):5053-64
1J:111028 Srinivas M, Ng L, Liu H, Jia L, Forrest D, Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta. Mol Endocrinol. 2006 Aug;20(8):1728-41
9J:108345 Stoykov I, Zandieh-Doulabi B, Moorman AF, Christoffels V, Wiersinga WM, Bakker O, Expression pattern and ontogenesis of thyroid hormone receptor isoforms in the mouse heart. J Endocrinol. 2006 May;189(2):231-45
1J:43644 Wei LN, Lee CH, Filipcik P, Chang L, Regulation of the mouse cellular retinoic acid-binding protein-I gene by thyroid hormone and retinoids in transgenic mouse embryos and P19 cells. J Endocrinol. 1997 Oct;155(1):35-46
8*J:108438 Yanagi Y, Takezawa S, Kato S, Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development. Invest Ophthalmol Vis Sci. 2002 Nov;43(11):3489-94
2*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory