Gene Expression Literature Summary

• Symbol: Tgfbr1
• Name: transforming growth factor, beta receptor I
• ID: MGI:98728

97 matching records from 97 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4	E4.5	E5.5	E6	E6.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)														1		1		2	3	1	7	2	5	3	6	3	5	1	7		1	1	9		1	1	7
In situ RNA (section)														2		2		1	4		4		6		10	1	5	1	4		2		1			1	4
Immunohistochemistry (whole mount)		1		1		1		1
In situ RNA (whole mount)														1		1		2			1		2				1									1
In situ reporter (knock in)																		1	1				1				2						1				2
Northern blot																																					3
Western blot																							3			1			1	1	1			1	1	1	4
RT-PCR	1	2	2	3	2	2	2	3	1	1	1	2	3		1	7	1	2	3	1	7	1	7	1	6	2	5	1	6	2	5		7	1		1	16
cDNA clones																																					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tgfbr1  transforming growth factor, beta receptor I   (Synonyms: Alk-5, ALK5, TbetaRI, TbetaR-I)
Results	Reference
9*	J:130902 Alejandre-Alcazar MA, Michiels-Corsten M, Vicencio AG, Reiss I, Ryu J, de Krijger RR, Haddad GG, Tibboel D, Seeger W, Eickelberg O, Morty RE, TGF-beta signaling is dynamically regulated during the alveolarization of rodent and human lungs. Dev Dyn. 2008 Jan;237(1):259-69
1	J:116889 Andersson O, Reissmann E, Ibanez CF, Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis. EMBO Rep. 2006 Aug;7(8):831-7
2	J:321831 Bai F, Wang C, Liu X, Hollern D, Liu S, Fan C, Liu C, Ren S, Herschkowitz JI, Zhu WG, Pei XH, Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFbetaR2 signaling pathway. Cell Death Dis. 2022 Mar 2;13(3):195
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:202725 Borges L, Iacovino M, Koyano-Nakagawa N, Baik J, Garry DJ, Kyba M, Perlingeiro RC, Expression levels of endoglin distinctively identify hematopoietic and endothelial progeny at different stages of yolk sac hematopoiesis. Stem Cells. 2013 Sep;31(9):1893-901
6	J:219394 Boroviak T, Loos R, Bertone P, Smith A, Nichols J, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28
1	J:314222 Celaya AM, Rodriguez-de la Rosa L, Bermudez-Munoz JM, Zubeldia JM, Roma-Mateo C, Avendano C, Pallardo FV, Varela-Nieto I, IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss. Cells. 2021 Jul 3;10(7)
2	J:124144 Chen F, Desai TJ, Qian J, Niederreither K, Lu J, Cardoso WV, Inhibition of Tgf{beta} signaling by endogenous retinoic acid is essential for primary lung bud induction. Development. 2007 Aug;134(16):2969-79
2*	J:306879 Chen L, Tao F, Zhang Y, Shu C, Xiang W, Yang L, Chen X, Hong Y, Chen B, Li K, Zhang W, Hao K, Ge F, Wang Z, Lyu J, Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfbeta signaling in mice. FEBS Lett. 2020 Sep;594(17):2881-2893
13*	J:74181 Chow JF, Lee KF, Chan ST, Yeung WS, Quantification of transforming growth factor beta1 (TGFbeta1) mRNA expression in mouse preimplantation embryos and determination of TGFbeta receptor (type I and type II) expression in mouse embryos and reproductive tract. Mol Hum Reprod. 2001 Nov;7(11):1047-56
5*	J:74075 Cui XM, Shuler CF, The TGF-beta type III receptor is localized to the medial edge epithelium during palatal fusion. Int J Dev Biol. 2000 Jun;44(4):397-402
1	J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
2	J:263837 Dave JM, Mirabella T, Weatherbee SD, Greif DM, Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain. Dev Cell. 2018 Mar 26;44(6):665-678.e6
2*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
7*	J:82773 Dichmann DS, Miller CP, Jensen J, Scott Heller R, Serup P, Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn. 2003 Apr;226(4):663-74
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:119289 Dudas M, Kim J, Li WY, Nagy A, Larsson J, Karlsson S, Chai Y, Kaartinen V, Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol. 2006 Aug 15;296(2):298-314
3*	J:87407 Dudas M, Nagy A, Laping NJ, Moustakas A, Kaartinen V, Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway. Dev Biol. 2004 Feb 1;266(1):96-108
3	J:105113 Dunker N, Krieglstein K, Reduced programmed cell death in the retina and defects in lens and cornea of Tgfbeta2(-/-) Tgfbeta3(-/-) double-deficient mice. Cell Tissue Res. 2003 Jul;313(1):1-10
1	J:228475 Foong RE, Shaw NC, Berry LJ, Hart PH, Gorman S, Zosky GR, Vitamin D deficiency causes airway hyperresponsiveness, increases airway smooth muscle mass, and reduces TGF-beta expression in the lungs of female BALB/c mice. Physiol Rep. 2014;2(3):e00276
1	J:140104 Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z, Serum response factor is required for sprouting angiogenesis and vascular integrity. Dev Cell. 2008 Sep;15(3):448-61
2*	J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44
1	J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24
2	J:174168 Gao Y, Li D, Han T, Sun Y, Zhang J, TGF-beta1 and TGFBR1 are expressed in ameloblasts and promote MMP20 expression. Anat Rec (Hoboken). 2009 Jun;292(6):885-90
2	J:171615 Georgas KM, Chiu HS, Lesieur E, Rumballe BA, Little MH, Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Dev Dyn. 2011 Jun;240(6):1600-12
3	J:176045 Gokoffski KK, Wu HH, Beites CL, Kim J, Kim EJ, Matzuk MM, Johnson JE, Lander AD, Calof AL, Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development. 2011 Oct;138(19):4131-42
1	J:86237 Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, Mummery C, Karlsson S, ten Dijke P, Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell. 2003 Oct;12(4):817-28
2*	J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:248980 Guo H, Kazadaeva Y, Ortega FE, Manjunath N, Desai TJ, Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
1	J:181586 Hald J, Galbo T, Rescan C, Radzikowski L, Sprinkel AE, Heimberg H, Ahnfelt-Ronne J, Jensen J, Scharfmann R, Gradwohl G, Kaestner KH, Stoeckert C Jr, Jensen JN, Madsen OD, Pancreatic islet and progenitor cell surface markers with cell sorting potential. Diabetologia. 2012 Jan;55(1):154-65
2	J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22
2*	J:218259 Hill CR, Jacobs BH, Brown CB, Barnett JV, Goudy SL, Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn. 2015 Feb;244(2):122-33
1	J:122868 Hong KH, Seki T, Oh SP, Activin receptor-like kinase 1 is essential for placental vascular development in mice. Lab Invest. 2007 Jul;87(7):670-9
4*	J:28212 Iseki S, Osumi-Yamashita N, Miyazono K, Franzen P, Ichijo H, Ohtani H, Hayashi Y, Eto K, Localization of transforming growth factor-beta type I and type II receptors in mouse development. Exp Cell Res. 1995 Aug;219(2):339-47
1	J:69420 Jaskoll T, Melnick M, Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations. Anat Rec. 1999 Nov 1;256(3):252-68
4	J:99244 Kim J, Wu HH, Lander AD, Lyons KM, Matzuk MM, Calof AL, GDF11 controls the timing of progenitor cell competence in developing retina. Science. 2005 Jun 24;308(5730):1927-30
1*	J:173348 Koide M, Ikeda K, Akakabe Y, Kitamura Y, Ueyama T, Matoba S, Yamada H, Okigaki M, Matsubara H, Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9472-7
4*	J:291779 Kolla L, Kelly MC, Mann ZF, Anaya-Rocha A, Ellis K, Lemons A, Palermo AT, So KS, Mays JC, Orvis J, Burns JC, Hertzano R, Driver EC, Kelley MW, Characterization of the development of the mouse cochlear epithelium at the single cell level. Nat Commun. 2020 May 13;11(1):2389
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
2	J:272613 Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR, USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
4	J:68770 Larsson J, Goumans MJ, Sjostrand LJ, van Rooijen MA, Ward D, Leveen P, Xu X, ten Dijke P, Mummery CL, Karlsson S, Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice. EMBO J. 2001 Apr 2;20(7):1663-73
1	J:142576 Lebeurrier N, Launay S, Macrez R, Maubert E, Legros H, Leclerc A, Jamin SP, Picard JY, Marret S, Laudenbach V, Berger P, Sonderegger P, Ali C, di Clemente N, Vivien D, Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. J Cell Sci. 2008 Oct 15;121(Pt 20):3357-65
2	J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19
1	J:198191 Li C, Li A, Xing Y, Li M, Chan B, Ouyang R, Taketo MM, Kucherlapati R, Borok Z, Minoo P, Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling. Dev Biol. 2013 Jun 1;378(1):13-24
1	J:278237 Li G, Tian L, Goodyer W, Kort EJ, Buikema JW, Xu A, Wu JC, Jovinge S, Wu SM, Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. Development. 2019 Jun 14;146(12):dev173476
1	J:143910 Li M, Li C, Liu YH, Xing Y, Hu L, Borok Z, Kwong KY, Minoo P, Mesodermal Deletion of Transforming Growth Factor-{beta} Receptor II Disrupts Lung Epithelial Morphogenesis: cross-talk between TGF-{beta} and Sonic hedgehog pathways. J Biol Chem. 2008 Dec 26;283(52):36257-64
2	J:308923 Li Z, Li D, Rao Y, Wei L, Liu M, Zheng G, Yao Y, Hou X, Chen Y, Ruan XZ, SCAP knockout in SM22alpha-Cre mice induces defective angiogenesis in the placental labyrinth. Biomed Pharmacother. 2021 Jan;133:111011
2	J:320190 Liu T, Wan RP, Tang LJ, Liu SJ, Li HJ, Zhao QH, Liao WP, Sun XF, Yi YH, Long YS, A MicroRNA Profile in Fmr1 Knockout Mice Reveals MicroRNA Expression Alterations with Possible Roles in Fragile X Syndrome. Mol Neurobiol. 2015;51(3):1053-63
2	J:281458 Lopes FM, Roberts NA, Zeef LA, Gardiner NJ, Woolf AS, Overactivity or blockade of transforming growth factor-beta each generate a specific ureter malformation. J Pathol. 2019 Dec;249(4):472-484
24*	J:51497 Mariano JM, Montuenga LM, Prentice MA, Cuttitta F, Jakowlew SB, Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis. Int J Dev Biol. 1998 Nov;42(8):1125-36
3	J:152864 Matsunobu T, Torigoe K, Ishikawa M, de Vega S, Kulkarni AB, Iwamoto Y, Yamada Y, Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development. Dev Biol. 2009 Aug 15;332(2):325-38
3	J:334074 McCoy AM, Lakhdari O, Shome S, Caoili K, Hernandez GE, Aghaeepour N, Butcher LD, Fisch K, Prince LS, Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development. Development. 2023 Mar 1;150(5):dev200839
1	J:187360 McKean DM, Niswander L, Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1(9):874-883
7*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
4	J:195695 Miles DC, Wakeling SI, Stringer JM, van den Bergen JA, Wilhelm D, Sinclair AH, Western PS, Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development. PLoS One. 2013;8(1):e54606
2*	J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109
4	J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84
1*	J:234115 Nik AM, Johansson JA, Ghiami M, Reyahi A, Carlsson P, Foxf2 is required for secondary palate development and Tgfbeta signaling in palatal shelf mesenchyme. Dev Biol. 2016 Jul 1;415(1):14-23
1	J:100384 Okano J, Takigawa T, Seki K, Suzuki S, Shiota K, Ishibashi M, Transforming growth factor beta2 promotes the formation of the mouse cochleovestibular ganglion in organ culture. Int J Dev Biol. 2005;49(1):23-31
2*	J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
1	J:143444 Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM, An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development. 2008 Nov;135(21):3599-610
1*	J:150963 Pavlinkova G, Salbaum JM, Kappen C, Maternal diabetes alters transcriptional programs in the developing embryo. BMC Genomics. 2009;10:274
3	J:230021 Peng Y, Song L, Zhao M, Harmelink C, Debenedittis P, Cui X, Wang Q, Jiao K, Critical roles of miRNA-mediated regulation of TGFbeta signalling during mouse cardiogenesis. Cardiovasc Res. 2014 Jul 15;103(2):258-67
1	J:291752 Portal C, Rompolas P, Lwigale P, Iomini C, Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse. Elife. 2019 Dec 17;8:e52423
1	J:239656 Reyahi A, Nik AM, Ghiami M, Gritli-Linde A, Ponten F, Johansson BR, Carlsson P, Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier. Dev Cell. 2015 Jul 06;34(1):19-32
1*	J:255859 Ries RJ, Yu W, Holton N, Cao H, Amendt BA, Inhibition of the miR-17-92 Cluster Separates Stages of Palatogenesis. J Dent Res. 2017 Oct;96(11):1257-1264
7*	J:51778 Roelen BA, Goumans MJ, Zwijsen A, Mummery CL, Identification of two distinct functions for TGF-beta in early mouse development. Differentiation. 1998 Nov;64(1):19-31
4	J:22323 Roelen BA, Lin HY, Knezevic V, Freund E, Mummery CL, Expression of TGF-beta s and their receptors during implantation and organogenesis of the mouse embryo. Dev Biol. 1994 Dec;166(2):716-28
1	J:301025 Seelan RS, Mukhopadhyay P, Philipose J, Greene RM, Pisano MM, Gestational folate deficiency alters embryonic gene expression and cell function. Differentiation. 2020 Nov 27;117:1-15
6	J:104918 Seki T, Hong KH, Oh SP, Nonoverlapping expression patterns of ALK1 and ALK5 reveal distinct roles of each receptor in vascular development. Lab Invest. 2006 Feb;86(2):116-29
1	J:197686 Shang Y, Doan CN, Arnold TD, Lee S, Tang AA, Reichardt LF, Huang EJ, Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-beta-TAK1-dependent mechanism. PLoS Biol. 2013;11(4):e1001527
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:130128 Siegenthaler JA, Miller MW, Generation of Cajal-Retzius neurons in mouse forebrain is regulated by transforming growth factor beta-Fox signaling pathways. Dev Biol. 2008 Jan 1;313(1):35-46
1	J:142286 Sridurongrit S, Larsson J, Schwartz R, Ruiz-Lozano P, Kaartinen V, Signaling via the Tgf-beta type I receptor Alk5 in heart development. Dev Biol. 2008 Oct 1;322(1):208-18
1	J:135895 Srinivasan Y, Lovicu FJ, Overbeek PA, Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest. 1998 Feb 1;101(3):625-34
2	J:82356 Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO, A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development. Mol Cell Biol. 2003 Mar;23(5):1817-31
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
2	J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5
1*	J:56561 Taya Y, O'Kane S, Ferguson MW, Pathogenesis of cleft palate in TGF-beta3 knockout mice. Development. 1999 Sep;126(17):3869-79
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
10	J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521
1	J:302089 Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T, The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget. 2016 Jun 21;7(25):37436-37455
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3	J:334587 Wang L, Lin L, Qi H, Chen J, Grossfeld P, Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction. Circ Res. 2022 Aug 19;131(5):371-387
4	J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579
1	J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578
5	J:212442 Wang ZP, Mu XY, Guo M, Wang YJ, Teng Z, Mao GP, Niu WB, Feng LZ, Zhao LH, Xia GL, Transforming growth factor-beta signaling participates in the maintenance of the primordial follicle pool in the mouse ovary. J Biol Chem. 2014 Mar 21;289(12):8299-311
1	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
1	J:224370 Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G, Kindlin-2 controls TGF-beta signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531
1	J:81451 Wu HH, Ivkovic S, Murray RC, Jaramillo S, Lyons KM, Johnson JE, Calof AL, Autoregulation of Neurogenesis by GDF11. Neuron. 2003 Jan 23;37(2):197-207
5	J:157922 Xing Y, Li C, Li A, Sridurongrit S, Tiozzo C, Bellusci S, Borok Z, Kaartinen V, Minoo P, Signaling via Alk5 controls the ontogeny of lung Clara cells. Development. 2010 Mar;137(5):825-33
1	J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554
1*	J:145581 Yamazaki S, Iwama A, Takayanagi S, Eto K, Ema H, Nakauchi H, TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Blood. 2009 Feb 5;113(6):1250-6
2	J:167938 Yi JJ, Barnes AP, Hand R, Polleux F, Ehlers MD, TGF-beta signaling specifies axons during brain development. Cell. 2010 Jul 9;142(1):144-57
2*	J:139188 Zhao H, Oka K, Bringas P, Kaartinen V, Chai Y, TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
3*	J:52557 Zwijsen A, Goumans MJ, Lawson KA, Van Rooijen MA, Mummery CL, Ectopic expression of the transforming growth factor beta type II receptor disrupts mesoderm organisation during mouse gastrulation. Dev Dyn. 1999 Feb;214(2):141-51