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Gene Expression Literature Summary
Symbol
Name
ID
Tgfb1
transforming growth factor, beta 1
MGI:98725

163 matching records from 163 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E2 E2.5 E3 E3.5 E4 E5.5 E6 E6.5 E7 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E A
In situ protein (section) 1 1 4 6 1 4 1 4 7 2 10 4 10 3 4 1 8 2 2 1 5 1 1 5 12
In situ RNA (section) 1 2 1 2 3 4 1 8 1 7 1 7 2 10 1 10 2 18 3 9 9 2 1 5 1 5 8
In situ protein (whole mount) 1 1 1 1 1
In situ RNA (whole mount) 1 3 1 1 1 1 2 1 1
In situ reporter (knock in) 1
Northern blot 1 2 1 2 1 2 1 2 3 3 3 2 2 3 5 1 2 2 1 8
Western blot 2 1 1 2 1 1 1 3
RT-PCR 1 1 1 1 1 1 1 1 2 7 1 6 2 3 3 12 4 15 4 11 6 13 3 7 4 5 3 4 2 8 1 1 2 23
cDNA clones 1
RNase protection 1 1 1 2 2 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tgfb1  transforming growth factor, beta 1   (Synonyms: Tgfb, Tgfb-1, TGFbeta1, TGF-beta1, TGF-beta 1)
Results  Reference
2*J:92174 Aberg T, Wang XP, Kim JH, Yamashiro T, Bei M, Rice R, Ryoo HM, Thesleff I, Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol. 2004 Jun 1;270(1):76-93
1J:207514 Acharjee S, Chung TK, Gopinadhan S, Shankar SR, Wang Y, Li L, Vercherat C, Gulbagci NT, Rossner M, Taneja R, Sharp-1 regulates TGF-beta signaling and skeletal muscle regeneration. J Cell Sci. 2014 Feb 1;127(Pt 3):599-608
15*J:33496 Akhurst RJ, Lehnert SA, Faissner A, Duffie E, TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development. 1990 Apr;108(4):645-56
2J:95764 Alappat SR, Zhang Z, Suzuki K, Zhang X, Liu H, Jiang R, Yamada G, Chen Y, The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice. Dev Biol. 2005 Jan 1;277(1):102-13
2J:152710 Aldinger KA, Lehmann OJ, Hudgins L, Chizhikov VV, Bassuk AG, Ades LC, Krantz ID, Dobyns WB, Millen KJ, FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation. Nat Genet. 2009 Sep;41(9):1037-42
1J:136394 Anthwal N, Chai Y, Tucker AS, The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary. Dev Dyn. 2008 Jun;237(6):1604-13
1J:150973 Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP, Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology. 2009 Jun;136(7):2325-33
6J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33
1J:78219 Aubin J, Dery U, Lemieux M, Chailler P, Jeannotte L, Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Development. 2002 Sep;129(17):4075-87
1J:130208 Blois SM, Ilarregui JM, Tometten M, Garcia M, Orsal AS, Cordo-Russo R, Toscano MA, Bianco GA, Kobelt P, Handjiski B, Tirado I, Markert UR, Klapp BF, Poirier F, Szekeres-Bartho J, Rabinovich GA, Arck PC, A pivotal role for galectin-1 in fetomaternal tolerance. Nat Med. 2007 Dec;13(12):1450-7
3*J:90291 Bohnsack BL, Lai L, Dolle P, Hirschi KK, Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Genes Dev. 2004 Jun 1;18(11):1345-58
2J:106770 Bohnsack BL, Lai L, Northrop JL, Justice MJ, Hirschi KK, Visceral endoderm function is regulated by quaking and required for vascular development. Genesis. 2006 Feb;44(2):93-104
1J:175788 Bolte C, Zhang Y, Wang IC, Kalin TV, Molkentin JD, Kalinichenko VV, Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development. PLoS One. 2011;6(7):e22217
1J:189446 Bonod-Bidaud C, Roulet M, Hansen U, Elsheikh A, Malbouyres M, Ricard-Blum S, Faye C, Vaganay E, Rousselle P, Ruggiero F, In vivo evidence for a bridging role of a collagen V subtype at the epidermis-dermis interface. J Invest Dermatol. 2012 Jul;132(7):1841-9
1J:202725 Borges L, Iacovino M, Koyano-Nakagawa N, Baik J, Garry DJ, Kyba M, Perlingeiro RC, Expression levels of endoglin distinctively identify hematopoietic and endothelial progeny at different stages of yolk sac hematopoiesis. Stem Cells. 2013 Sep;31(9):1893-901
1J:72639 Bragg AD, Moses HL, Serra R, Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development. Mech Dev. 2001 Nov;109(1):13-26
1J:78596 Brandau O, Aszodi A, Hunziker EB, Neame PJ, Vestweber D, Fassler R, Chondromodulin I is dispensable during enchondral ossification and eye development. Mol Cell Biol. 2002 Sep;22(18):6627-35
1*J:93240 Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y, Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc Natl Acad Sci U S A. 2004 Dec 9;101(45):16016-21
7*J:18919 Buchman VL, Sporn M, Davies AM, Role of transforming growth factor-beta isoforms in regulating the expression of nerve growth factor and neurotrophin-3 mRNA levels in embryonic cutaneous cells at different stages of development. Development. 1994 Jun;120(6):1621-9
2J:98373 Carvalho RL, Jonker L, Goumans MJ, Larsson J, Bouwman P, Karlsson S, Dijke PT, Arthur HM, Mummery CL, Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development. 2004 Dec;131(24):6237-47
2J:17122 Chai Y, Mah A, Crohin C, Groff S, Bringas P Jr, Le T, Santos V, Slavkin HC, Specific transforming growth factor-beta subtypes regulate embryonic mouse Meckel's cartilage and tooth development. Dev Biol. 1994 Mar;162(1):85-103
1J:67398 Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ, The characterization of mice with a targeted combined deficiency of protein c and factor XI. Am J Pathol. 2001 Feb;158(2):469-79
2J:124144 Chen F, Desai TJ, Qian J, Niederreither K, Lu J, Cardoso WV, Inhibition of Tgf{beta} signaling by endogenous retinoic acid is essential for primary lung bud induction. Development. 2007 Aug;134(16):2969-79
1J:145561 Chen YT, Hims MM, Shetty RS, Mull J, Liu L, Leyne M, Slaugenhaupt SA, Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. Mol Cell Biol. 2009 Feb;29(3):736-44
3J:16945 Cheng HL, Schneider SL, Kane CM, Gollnick SO, Grande C, Thompson D, Pietrzak E, Tomasi TB, TGF-beta 2 gene and protein expression in maternal and fetal tissues at various stages of murine development. J Reprod Immunol. 1993 Nov;25(2):133-48
1J:165936 Choocheep K, Hatano S, Takagi H, Watanabe H, Kimata K, Kongtawelert P, Watanabe H, Versican facilitates chondrocyte differentiation and regulates joint morphogenesis. J Biol Chem. 2010 Jul 2;285(27):21114-25
7J:74181 Chow JF, Lee KF, Chan ST, Yeung WS, Quantification of transforming growth factor beta1 (TGFbeta1) mRNA expression in mouse preimplantation embryos and determination of TGFbeta receptor (type I and type II) expression in mouse embryos and reproductive tract. Mol Hum Reprod. 2001 Nov;7(11):1047-56
1J:40384 Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH, Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr;60(2):81-91
6J:63257 Crisera CA, Maldonado TS, Kadison AS, Li M, Alkasab SL, Longaker MT, Gittes GK, Transforming growth factor-beta 1 in the developing mouse pancreas: a potential regulator of exocrine differentiation. Differentiation. 2000 May;65(5):255-9
3J:171226 Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B, GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64
2J:190996 d'Amaro R, Scheidegger R, Blumer S, Pazera P, Katsaros C, Graf D, Chiquet M, Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis. Front Physiol. 2012;3:377
2J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400
5J:51265 Degitz SJ, Morris D, Foley GL, Francis BM, Role of TGF-beta in RA-induced cleft palate in CD-1 mice. Teratology. 1998 Nov;58(5):197-204
1*J:10745 Denhez F, Lafyatis R, Kondaiah P, Roberts AB, Sporn MB, Cloning by polymerase chain reaction of a new mouse TGF-beta, mTGF-beta 3. Growth Factors. 1990;3(2):139-46
1J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
7*J:82773 Dichmann DS, Miller CP, Jensen J, Scott Heller R, Serup P, Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas. Dev Dyn. 2003 Apr;226(4):663-74
6*J:4372 Dickson MC, Slager HG, Duffie E, Mummery CL, Akhurst RJ, RNA and protein localisations of TGF beta 2 in the early mouse embryo suggest an involvement in cardiac development. Development. 1993 Feb;117(2):625-39
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5J:198451 El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G, Smad signaling pathways regulate pancreatic endocrine development. Dev Biol. 2013 Jun 15;378(2):83-93
1J:149800 Falk S, Wurdak H, Ittner LM, Ille F, Sumara G, Schmid MT, Draganova K, Lang KS, Paratore C, Leveen P, Suter U, Karlsson S, Born W, Ricci R, Gotz M, Sommer L, Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell. 2008 May 8;2(5):472-83
3J:49552 Ferguson CA, Tucker AS, Christensen L, Lau AL, Matzuk MM, Sharpe PT, Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev. 1998 Aug 15;12(16):2636-49
4J:3784 Ferguson MW, Sharpe PM, Thomas BL, Beck F, Differential expression of insulin-like growth factors I and II (IGF I and II), mRNA, peptide and binding protein 1 during mouse palate development: comparison with TGF beta peptide distribution. J Anat. 1992 Oct;181(Pt 2):219-38
6*J:32953 Fitzpatrick DR, Denhez F, Kondaiah P, Akhurst RJ, Differential expression of TGF beta isoforms in murine palatogenesis. Development. 1990 Jul;109(3):585-95
3J:31836 Flanders KC, Ludecke G, Engels S, Cissel DS, Roberts AB, Kondaiah P, Lafyatis R, Sporn MB, Unsicker K, Localization and actions of transforming growth factor-beta s in the embryonic nervous system. Development. 1991 Sep;113(1):183-91
1J:140104 Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z, Serum response factor is required for sprouting angiogenesis and vascular integrity. Dev Cell. 2008 Sep;15(3):448-61
1J:73345 Gaikwad JS, Cavender A, D'Souza RN, Identification of tooth-specific downstream targets of Runx2. Gene. 2001 Nov 14;279(1):91-7
2J:174168 Gao Y, Li D, Han T, Sun Y, Zhang J, TGF-beta1 and TGFBR1 are expressed in ameloblasts and promote MMP20 expression. Anat Rec (Hoboken). 2009 Jun;292(6):885-90
3*J:21746 Gehris AL, Pisano MM, Nugent P, Greene RM, Regulation of TGF beta 3 gene expression in embryonic palatal tissue. In Vitro Cell Dev Biol Anim. 1994 Oct;30A(10):671-9
4*J:30189 Ginsburg GT, Royster D, Kassabian G, Shuler CF, Dougherty WR, Sank AC, Mesenchymal commitment to digital joint formation. Ann Plast Surg. 1995 Jul;35(1):95-104
1J:31833 Godin I, Wylie CC, TGF beta 1 inhibits proliferation and has a chemotropic effect on mouse primordial germ cells in culture. Development. 1991 Dec;113(4):1451-7
2*J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77
6J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27
4J:154032 Guo Y, Zhang X, Huang J, Zeng Y, Liu W, Geng C, Li KW, Yang D, Wu S, Wei H, Han Z, Qian X, Jiang Y, He F, Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. PLoS One. 2009;4(10):e7641
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3J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1*J:139635 Huang X, Goudy SL, Ketova T, Litingtung Y, Chiang C, Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development. Dev Dyn. 2008 Sep 24;237(10):3079-3087
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4J:166656 Ida-Yonemochi H, Nakajima M, Saku T, Heparanase, heparan sulfate and perlecan distribution along with the vascular penetration during stellate reticulum retraction in the mouse enamel organ. Arch Oral Biol. 2010 Oct;55(10):778-87
1J:119566 Ishimura A, Ng JK, Taira M, Young SG, Osada S, Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28
8J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340
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1J:192973 Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S, SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-beta and bone morphogenetic protein pathways. J Biol Chem. 2012 Aug 17;287(34):29101-13
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1J:187713 Li J, Bowens N, Cheng L, Zhu X, Chen M, Hannenhalli S, Cappola TP, Parmacek MS, Myocardin-like protein 2 regulates TGFbeta signaling in embryonic stem cells and the developing vasculature. Development. 2012 Oct;139(19):3531-42
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1*J:66591 Mahlapuu M, Ormestad M, Enerback S, Carlsson P, The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development. 2001 Jan;128(2):155-66
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1J:145175 Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V, Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. Dev Biol. 2009 Feb 15;326(2):368-77
10*J:1989 Manova K, Paynton BV, Bachvarova RF, Expression of activins and TGF beta 1 and beta 2 RNAs in early postimplantation mouse embryos and uterine decidua. Mech Dev. 1992 Feb;36(3):141-52
4J:87413 Martinez-Alvarez C, Blanco MJ, Perez R, Rabadan MA, Aparicio M, Resel E, Martinez T, Nieto MA, Snail family members and cell survival in physiological and pathological cleft palates. Dev Biol. 2004 Jan 1;265(1):207-18
4J:80722 McLennan IS, Koishi K, The transforming growth factor-betas: multifaceted regulators of the development and maintenance of skeletal muscles, motoneurons and Schwann cells. Int J Dev Biol. 2002;46(4):559-67
7J:136358 Mecha M, Rabadan MA, Pena-Melian A, Valencia M, Mondejar T, Blanco MJ, Expression of TGF-betas in the embryonic nervous system: analysis of interbalance between isoforms. Dev Dyn. 2008 Jun;237(6):1709-17
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