Gene Expression Literature Summary

• Symbol: Sox14
• Name: SRY (sex determining region Y)-box 14
• ID: MGI:98362

47 matching records from 47 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11.5	E12.5	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)	1		6	1			2			1		2
In situ RNA (section)	2	8	13	9	4		3		5		6	6
In situ RNA (whole mount)	1	4	1				1
In situ reporter (knock in)	1	1	4		1				1	2	2	4
RT-PCR			1			1		1				2
cDNA clones		1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox14  SRY (sex determining region Y)-box 14
Results	Reference
1	J:203421 Achim K, Peltopuro P, Lahti L, Tsai HH, Zachariah A, Astrand M, Salminen M, Rowitch D, Partanen J, The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors. Biol Open. 2013;2(10):990-7
1	J:288305 Aslanpour S, Rosin JM, Balakrishnan A, Klenin N, Blot F, Gradwohl G, Schuurmans C, Kurrasch DM, Ascl1 is required to specify a subset of ventromedial hypothalamic neurons. Development. 2020 May 28;147(10):dev180067
3	J:238975 Clovis YM, Seo SY, Kwon JS, Rhee JC, Yeo S, Lee JW, Lee S, Lee SK, Chx10 Consolidates V2a Interneuron Identity through Two Distinct Gene Repression Modes. Cell Rep. 2016 Aug 09;16(6):1642-52
2	J:299679 Debrulle S, Baudouin C, Hidalgo-Figueroa M, Pelosi B, Francius C, Rucchin V, Ronellenfitch K, Chow RL, Tissir F, Lee SK, Clotman F, Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development. Cell Mol Life Sci. 2020 Oct;77(20):4117-4131
9	J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:278245 Guo Q, Li JYH, Defining developmental diversification of diencephalon neurons through single cell gene expression profiling. Development. 2019 Apr 1;146(12):dev174284
1*	J:62183 Hargrave M, James K, Nield K, Toomes C, Georgas K, Sullivan T, Verzijl HT, Oley CA, Little M, De Jonghe P, Kwon JM, Kremer H, Dixon MJ, Timmerman V, Yamada T, Koopman P, Fine mapping of the neurally expressed gene SOX14 to human 3q23, relative to three congenital diseases. Hum Genet. 2000 Apr;106(4):432-9
2	J:60704 Hargrave M, James K, Yamada T, Koopman P, Sox14 maps to mouse chromosome 9 and shows no mutations in the neurological mouse mutants ducky and tippy. Mamm Genome. 2000 Mar;11(3):231-3
4*	J:60974 Hargrave M, Karunaratne A, Cox L, Wood S, Koopman P, Yamada T, The HMG box transcription factor gene Sox14 marks a novel subset of ventral interneurons and is regulated by sonic hedgehog. Dev Biol. 2000 Mar 1;219(1):142-53
1*	J:86406 Hashimoto-Torii K, Motoyama J, Hui CC, Kuroiwa A, Nakafuku M, Shimamura K, Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus. Mech Dev. 2003 Oct;120(10):1097-111
1	J:119561 Hirata T, Nakazawa M, Muraoka O, Nakayama R, Suda Y, Hibi M, Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. Development. 2006 Oct;133(20):3993-4004
1	J:224836 Hoch RV, Lindtner S, Price JD, Rubenstein JL, OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum. Cell Rep. 2015 Jul 21;12(3):482-94
3	J:279329 Huisman C, Cho H, Brock O, Lim SJ, Youn SM, Park Y, Kim S, Lee SK, Delogu A, Lee JW, Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators. Nat Commun. 2019 Aug 16;10(1):3696
1	J:301404 Jager P, Moore G, Calpin P, Durmishi X, Salgarella I, Menage L, Kita Y, Wang Y, Kim DW, Blackshaw S, Schultz SR, Brickley S, Shimogori T, Delogu A, Dual midbrain and forebrain origins of thalamic inhibitory interneurons. Elife. 2021 Feb 1;10:e59272
3	J:243238 Jager P, Ye Z, Yu X, Zagoraiou L, Prekop HT, Partanen J, Jessell TM, Wisden W, Brickley SG, Delogu A, Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus. Nat Commun. 2016 Dec 08;7:13579
1	J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41
5*	J:229536 Kawasaki K, Kawasaki M, Watanabe M, Idrus E, Nagai T, Oommen S, Maeda T, Hagiwara N, Que J, Sharpe PT, Ohazama A, Expression of Sox genes in tooth development. Int J Dev Biol. 2015;59(10-12):471-8
1	J:295412 Kim DW, Washington PW, Wang ZQ, Lin SH, Sun C, Ismail BT, Wang H, Jiang L, Blackshaw S, The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development. Nat Commun. 2020 Aug 31;11(1):4360
1	J:266544 Kim J, Choi TI, Park S, Kim MH, Kim CH, Lee S, Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains. Development. 2018 Sep 3;145(17):dev165340
1	J:326949 Kirjavainen A, Singh P, Lahti L, Seja P, Lelkes Z, Makkonen A, Kilpinen S, Ono Y, Salminen M, Aitta-Aho T, Stenberg T, Molchanova S, Achim K, Partanen J, Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons. Development. 2022 Jul 15;149(14):dev200937
2	J:130568 Kurrasch DM, Cheung CC, Lee FY, Tran PV, Hata K, Ingraham HA, The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. J Neurosci. 2007 Dec 12;27(50):13624-34
3	J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29
1	J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758
1	J:184232 Lee K, Tan J, Morris MB, Rizzoti K, Hughes J, Cheah PS, Felquer F, Liu X, Piltz S, Lovell-Badge R, Thomas PQ, Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice. PLoS One. 2012;7(1):e29041
1	J:293412 Lipiec MA, Bem J, Kozinski K, Chakraborty C, Urban-Ciecko J, Zajkowski T, Dabrowski M, Szewczyk LM, Toval A, Ferran JL, Nagalski A, Wisniewska MB, TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus. Development. 2020 Aug 25;147(16):dev190181
5	J:310819 Makrides N, Panayiotou E, Fanis P, Karaiskos C, Lapathitis G, Malas S, Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain. Front Mol Neurosci. 2018;11:152
1	J:284129 Meier S, Alfonsi F, Kurniawan ND, Milne MR, Kasherman MA, Delogu A, Piper M, Coulson EJ, The p75 neurotrophin receptor is required for the survival of neuronal progenitors and normal formation of the basal forebrain, striatum, thalamus and neocortex. Development. 2019 Sep 18;146(18):dev181933
8	J:305279 Morello F, Borshagovski D, Survila M, Tikker L, Sadik-Ogli S, Kirjavainen A, Estartus N, Knaapi L, Lahti L, Toronen P, Mazutis L, Delogu A, Salminen M, Achim K, Partanen J, Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain. Cell Rep. 2020 Oct 13;33(2):108268
1	J:336866 Puelles L, Hidalgo-Sanchez M, The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer. Int J Mol Sci. 2023 Jun 5;24(11)
1	J:235958 Rousso DL, Qiao M, Kagan RD, Yamagata M, Palmiter RD, Sanes JR, Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Cell Rep. 2016 May 31;15(9):1930-44
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
2	J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91
1*	J:171106 Suzuki-Hirano A, Ogawa M, Kataoka A, Yoshida AC, Itoh D, Ueno M, Blackshaw S, Shimogori T, Dynamic spatiotemporal gene expression in embryonic mouse thalamus. J Comp Neurol. 2011 Feb 15;519(3):528-43
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:297100 Tikker L, Casarotto P, Singh P, Biojone C, Piepponen TP, Estartus N, Seelbach A, Sridharan R, Laukkanen L, Castren E, Partanen J, Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes and Increased Anxiety-Like Behavior. J Neurosci. 2020 Nov 4;40(45):8669-8682
1	J:171421 Vandunk C, Hunter LA, Gray PA, Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
1	J:188110 Virolainen SM, Achim K, Peltopuro P, Salminen M, Partanen J, Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres. Development. 2012 Oct;139(20):3795-805
1	J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97
1	J:321501 Wang W, Cho H, Lee JW, Lee SK, The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development. Nat Commun. 2022 Feb 17;13(1):958
3*	J:235366 Watanabe M, Kawasaki K, Kawasaki M, Portaveetus T, Oommen S, Blackburn J, Nagai T, Kitamura A, Nishikawa A, Kodama Y, Takagi R, Maeda T, Sharpe PT, Ohazama A, Spatio-temporal expression of Sox genes in murine palatogenesis. Gene Expr Patterns. 2016 Jul;21(2):111-8
2	J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883
1	J:157468 Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB, A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron. 2009 Dec 10;64(5):645-62
1	J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879