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Gene Expression Literature Summary
Symbol
Name
ID
Rxra
retinoid X receptor alpha
MGI:98214

56 matching records from 56 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1.5 E2 E2.5 E3 E3.5 E4.5 E5 E5.5 E6 E6.5 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E19.5 E A
In situ protein (section) 1 1 1 2 2 2 4 1 5 2 1 1 1 1 4
In situ RNA (section) 1 2 1 1 3 3 3 1 5 1 6 1 4 1 1 3 2 1 2 1 2 10
In situ RNA (whole mount) 1 1 2 1 1 1 1
Northern blot 1 1 1 1 3 1 1 1 3 1 1 2 1 1 1 2 1 1 3
Western blot 1 1 1 1 4 1 2 1 1 1 1 1
RT-PCR 1 1 1 1 2 1 1 1 2 1 1 1 2 1 1 5 2 2 4 1 3 4 1 4 1 8
cDNA clones 1 1 1
RNase protection 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Rxra  retinoid X receptor alpha   (Synonyms: 9530071D11Rik, RXRalpha1, RXR alpha 1)
Results  Reference
3*J:131720 Aquino JB, Marmigere F, Lallemend F, Lundgren TK, Villar MJ, Wegner M, Ernfors P, Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues. Gene Expr Patterns. 2008 Apr;8(4):217-26
2J:32973 Bertolino E, Wildt S, Richards G, Clerc RG, Expression of a novel murine homeobox gene in the developing cerebellar external granular layer during its proliferation. Dev Dyn. 1996 Apr;205(4):410-20
4J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203
1J:108333 Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P, Retinoid signaling determines germ cell fate in mice. Science. 2006 Apr 28;312(5773):596-600
1J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62
2J:182838 Chen X, Liu Z, Xu J, The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival. Mol Endocrinol. 2010 Oct;24(10):1917-34
4J:81585 Chinoy MR, Nielsen HC, Volpe MV, Mesenchymal nuclear transcription factors in nitrofen-induced hypoplastic lung. J Surg Res. 2002 Dec;108(2):203-11
4J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
3*J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1J:171491 Clugston RD, Zhang W, Alvarez S, de Lera AR, Greer JJ, Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia. Am J Respir Cell Mol Biol. 2010 Mar;42(3):276-85
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
17*J:17147 Dolle P, Fraulob V, Kastner P, Chambon P, Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994 Feb;45(2):91-104
3*J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
4J:84284 Ghoshal S, Pasham S, Odom DP, Furr HC, McGrane MM, Vitamin A depletion is associated with low phosphoenolpyruvate carboxykinase mRNA levels during late fetal development and at birth in mice. J Nutr. 2003 Jul;133(7):2131-6
3*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
3J:170840 Guadix JA, Ruiz-Villalba A, Lettice L, Velecela V, Munoz-Chapuli R, Hastie ND, Perez-Pomares JM, Martinez-Estrada OM, Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2. Development. 2011 Mar;138(6):1093-7
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
7*J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705
5J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81
2J:130203 Ijpenberg A, Perez-Pomares JM, Guadix JA, Carmona R, Portillo-Sanchez V, Macias D, Hohenstein P, Miles CM, Hastie ND, Munoz-Chapuli R, Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis. Dev Biol. 2007 Dec 1;312(1):157-70
8*J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207
4J:20550 Kastner P, Grondona JM, Mark M, Gansmuller A, LeMeur M, Decimo D, Vonesch JL, Dolle P, Chambon P, Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell. 1994 Sep 23;78(6):987-1003
4J:81047 Kobayashi H, Spilde TL, Bhatia AM, Buckingham RB, Hembree MJ, Prasadan K, Preuett BL, Imamura M, Gittes GK, Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions. Gastroenterology. 2002 Oct;123(4):1331-40
2J:34890 Krezel W, Dupe V, Mark M, Dierich A, Kastner P, Chambon P, RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable. Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9010-4
7J:56144 Lim H, Gupta RA, Ma WG, Paria BC, Moller DE, Morrow JD, DuBois RN, Trzaskos JM, Dey SK, Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev. 1999 Jun 15;13(12):1561-74
9J:98265 Makita T, Duncan SA, Sucov HM, Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation. Dev Biol. 2005 Apr 1;280(1):59-72
17J:2326 Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE, Kakizuka A, Evans RM, Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev. 1992 Mar;6(3):329-44
2J:146761 Mascrez B, Ghyselinck NB, Chambon P, Mark M, A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4272-7
2*J:50515 Mascrez B, Mark M, Dierich A, Ghyselinck NB, Kastner P, Chambon P, The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development. Development. 1998 Dec;125(23):4691-707
1*J:69853 Mascrez B, Mark M, Krezel W, Dupe V, LeMeur M, Ghyselinck NB, Chambon P, Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha. Development. 2001 Jun;128(11):2049-62
4*J:72759 McCaffery P, Wagner E, O'Neil J, Petkovich M, Drager UC, Dorsal and ventral rentinoic territories defined by retinoic acid synthesis, break-down and nuclear receptor expression. Mech Dev. 1999 Jul;85(1-2):203-14
5J:69008 Mori M, Ghyselinck NB, Chambon P, Mark M, Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes. Invest Ophthalmol Vis Sci. 2001 May;42(6):1312-8
1J:88451 Mori M, Metzger D, Picaud S, Hindelang C, Simonutti M, Sahel J, Chambon P, Mark M, Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium. Am J Pathol. 2004 Feb;164(2):701-10
1J:66247 Naltner A, Wert S, Whitsett JA, Yan C, Temporal/spatial expression of nuclear receptor coactivators in the mouse lung. Am J Physiol Lung Cell Mol Physiol. 2000 Dec;279(6):L1066-74
4*J:88404 Nishizawa H, Manabe N, Morita M, Sugimoto M, Imanishi S, Miyamoto H, Effects of in utero exposure to bisphenol A on expression of RARalpha and RXRalpha mRNAs in murine embryos. J Reprod Dev. 2003 Dec;49(6):539-45
2J:100386 Nishizawa H, Morita M, Sugimoto M, Imanishi S, Manabe N, Effects of in utero exposure to bisphenol a on mRNA expression of arylhydrocarbon and retinoid receptors in murine embryos. J Reprod Dev. 2005 Jun;51(3):315-24
2J:74219 Ogino Y, Suzuki K, Haraguchi R, Satoh Y, Dolle P, Yamada G, External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium. Ann N Y Acad Sci. 2001 Dec;948:13-31
4J:57264 Raz Y, Kelley MW, Retinoic acid signaling is necessary for the development of the organ of Corti. Dev Biol. 1999 Sep 1;213(1):180-93
1J:103712 Roberts MR, Hendrickson A, McGuire CR, Reh TA, Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina. Invest Ophthalmol Vis Sci. 2005 Aug;46(8):2897-904
1*J:21075 Rochette-Egly C, Lutz Y, Pfister V, Heyberger S, Scheuer I, Chambon P, Gaub MP, Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies. Biochem Biophys Res Commun. 1994 Oct 28;204(2):525-36
1J:46635 Romand R, Sapin V, Dolle P, Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear. J Comp Neurol. 1998 Apr 13;393(3):298-308
4J:44230 Sapin V, Dolle P, Hindelang C, Kastner P, Chambon P, Defects of the chorioallantoic placenta in mouse RXRalpha null fetuses. Dev Biol. 1997 Nov 1;191(1):29-41
11J:38200 Sapin V, Ward SJ, Bronner S, Chambon P, Dolle P, Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse. Dev Dyn. 1997 Feb;208(2):199-210
2*J:139174 Sato Y, Heuckeroth RO, Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro. Dev Biol. 2008 Aug 1;320(1):185-98
3*J:18047 Sucov HM, Dyson E, Gumeringer CL, Price J, Chien KR, Evans RM, RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev. 1994 May 1;8(9):1007-18
2J:115933 Suh JM, Yu CT, Tang K, Tanaka T, Kodama T, Tsai MJ, Tsai SY, The expression profiles of nuclear receptors in the developing and adult kidney. Mol Endocrinol. 2006 Dec;20(12):3412-20
3J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588
2J:150707 Uehara M, Yashiro K, Takaoka K, Yamamoto M, Hamada H, Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning. Genes Dev. 2009 Jul 15;23(14):1689-98
4*J:61711 Ulven SM, Gundersen TE, Weedon MS, Landaas VO, Sakhi AK, Fromm SH, Geronimo BA, Moskaug JO, Blomhoff R, Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid. Dev Biol. 2000 Apr 15;220(2):379-91
1J:171421 Vandunk C, Hunter LA, Gray PA, Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus. J Neurosci. 2011 Apr 27;31(17):6457-67
2*J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33
1J:78364 Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Prabhakar NR, Herrup K, Conlon RA, Hoit BD, Watanabe M, Yang YC, The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10488-93
2*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1*J:42054 Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine K, Yoshihara Y , Kawakami T , Arioka K , Sato H , Uchiyama Y , Masushige S , Fukamizu A , Matsumoto T , Kato S, Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet. 1997 Aug;16(4):391-6
1J:195854 Zhu Y, Pires KM, Whitehead KJ, Olsen CD, Wayment B, Zhang YC, Bugger H, Ilkun O, Litwin SE, Thomas G, Kozma SC, Abel ED, Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth. PLoS One. 2013;8(1):e54221

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory