Gene Expression Literature Summary

• Symbol: Por
• Name: cytochrome p450 oxidoreductase
• ID: MGI:97744

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E7.5	E8	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)							1	1	1					1		2
In situ RNA (section)		1			1	1		1	1	3	1	1	1		1	1
Immunohistochemistry (whole mount)					1
In situ RNA (whole mount)			1		1	3	1
In situ reporter (knock in)							1									1
Western blot						2	1	1		1						1
RT-PCR	1	2		1	2	1				2	2	1	1			3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Por  cytochrome p450 oxidoreductase   (Synonyms: 4933424M13Rik, CPR, CYPOR, NADH cytochrome P450 oxydoreductase)
Results	Reference
5	J:249535 Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD, A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism. Nat Commun. 2017 Jun 28;8(1):39
4*	J:155985 Budefeld T, Jezek D, Rozman D, Majdic G, Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes. Anat Histol Embryol. 2009 Nov;38(6):461-6
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:27992 Keeney DS, Ikeda Y, Waterman MR, Parker KL, Cholesterol side-chain cleavage cytochrome P450 gene expression in the primitive gut of the mouse embryo does not require steroidogenic factor 1. Mol Endocrinol. 1995 Aug;9(8):1091-8
3*	J:29760 Keeney DS, Jenkins CM, Waterman MR, Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo. Endocrinology. 1995 Nov;136(11):4872-9
16*	J:58885 Keeney DS, Waterman MR, Two novel sites of expression of NADPH cytochrome P450 reductase during murine embryogenesis: limb mesenchyme and developing olfactory neuroepithelia. Dev Dyn. 1999 Dec;216(4-5):511-7
1	J:111164 Notarnicola C, Malki S, Berta P, Poulat F, Boizet-Bonhoure B, Transient expression of SOX9 protein during follicular development in the adult mouse ovary. Gene Expr Patterns. 2006 Oct;6(7):695-702
1	J:85043 Otto DM, Henderson CJ, Carrie D, Davey M, Gundersen TE, Blomhoff R, Adams RH, Tickle C, Wolf CR, Identification of novel roles of the cytochrome p450 system in early embryogenesis: effects on vasculogenesis and retinoic Acid homeostasis. Mol Cell Biol. 2003 Sep;23(17):6103-16
6	J:118803 Ribes V, Otto DM, Dickmann L, Schmidt K, Schuhbaur B, Henderson C, Blomhoff R, Wolf CR, Tickle C, Dolle P, Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis. Dev Biol. 2007 Mar 1;303(1):66-81
5	J:148989 Schmidt K, Hughes C, Chudek JA, Goodyear SR, Aspden RM, Talbot R, Gundersen TE, Blomhoff R, Henderson C, Wolf CR, Tickle C, Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb. Mol Cell Biol. 2009 May;29(10):2716-29
1	J:74666 Shen AL, O'Leary KA, Kasper CB, Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductase. J Biol Chem. 2002 Feb 22;277(8):6536-41
2*	J:32243 Stromstedt M, Keeney DS, Waterman MR, Paria BC, Conley AJ, Dey SK, Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis. Mol Reprod Dev. 1996 Apr;43(4):428-36
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6