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Gene Expression Literature Summary
POU domain, class 1, transcription factor 1

64 matching records from 64 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 8 4 1 8 6 5 10
In situ RNA (section) 1 1 8 1 8 13 1 6 2 9 1 4 1 7
In situ RNA (whole mount) 1 2 1 1
Northern blot 1
RT-PCR 3 3 2 1 2 4
RNase protection 1 1 1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pou1f1  POU domain, class 1, transcription factor 1   (Synonyms: GHF-1, Hmp1, Pit1, Pit-1, Pit1-rs1, Snell dwarf)
Results  Reference
4J:30290 Andersen B, Pearse RV 2nd, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG, The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec;172(2):495-503
1J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34
2J:56185 Bentley CA, Zidehsarai MP, Grindley JC, Parlow AF, Barth-Hall S, Roberts VJ, Pax6 is implicated in murine pituitary endocrine function. Endocrine. 1999 Apr;10(2):171-7
1J:169150 Bharti K, Gasper M, Bertuzzi S, Arnheiter H, Lack of the ventral anterior homeodomain transcription factor VAX1 leads to induction of a second pituitary. Development. 2011 Mar;138(5):873-8
2J:147778 Bilodeau S, Roussel-Gervais A, Drouin J, Distinct developmental roles of cell cycle inhibitors p57Kip2 and p27Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells. Mol Cell Biol. 2009 Apr;29(7):1895-908
1J:41856 Bosse R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC , Missale C , Caron MG, Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 1997 Jul;19(1):127-38
3J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60
3J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21
1J:99227 Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ, PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol. 2005 Jul;19(7):1893-903
2*J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
1*J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207
3J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98
1J:171477 Davis SW, Mortensen AH, Camper SA, Birthdating studies reshape models for pituitary gland cell specification. Dev Biol. 2011 Apr 15;352(2):215-27
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
7J:36227 Dominov JA, Miller JB, POU homeodomain genes and myogenesis. Dev Genet. 1996;19(2):108-18
2*J:66992 Douglas KR, Camper SA, Partial transcriptome of the developing pituitary gland. Genomics. 2000 Dec 15;70(3):335-46
1J:106071 Ezzat S, Mader R, Fischer S, Yu S, Ackerley C, Asa SL, An essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary-mediated somatic growth. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2214-9
2J:132812 Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC, SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12
3J:37083 Gage PJ, Brinkmeier ML, Scarlett LM, Knapp LT, Camper SA, Mahon KA, The Ames dwarf gene, df, is required early in pituitary ontogeny for the extinction of Rpx transcription and initiation of lineage-specific cell proliferation. Mol Endocrinol. 1996 Dec;10(12):1570-81
3J:174144 Gaston-Massuet C, Andoniadou CL, Signore M, Jayakody SA, Charolidi N, Kyeyune R, Vernay B, Jacques TS, Taketo MM, Le Tissier P, Dattani MT, Martinez-Barbera JP, From the Cover: Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11482-7
2J:142425 Gaston-Massuet C, Andoniadou CL, Signore M, Sajedi E, Bird S, Turner JM, Martinez-Barbera JP, Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development. Dev Biol. 2008 Dec 15;324(2):322-33
2J:229902 Gaston-Massuet C, McCabe MJ, Scagliotti V, Young RM, Carreno G, Gregory LC, Jayakody SA, Pozzi S, Gualtieri A, Basu B, Koniordou M, Wu CI, Bancalari RE, Rahikkala E, Veijola R, Lopponen T, Graziola F, Turton J, Signore M, Mousavy Gharavy SN, Charolidi N, Sokol SY, Andoniadou CL, Wilson SW, Merrill BJ, Dattani MT, Martinez-Barbera JP, Transcription factor 7-like 1 is involved in hypothalamo-pituitary axis development in mice and humans. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E548-57
1J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88
2*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
2*J:30820 Hermesz E, Mackem S, Mahon KA, Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo. Development. 1996 Jan;122(1):41-52
1J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61
3J:191667 Jayakody SA, Andoniadou CL, Gaston-Massuet C, Signore M, Cariboni A, Bouloux PM, Le Tissier P, Pevny LH, Dattani MT, Martinez-Barbera JP, SOX2 regulates the hypothalamic-pituitary axis at multiple levels. J Clin Invest. 2012 Oct 1;122(10):3635-46
2*J:33102 Lin C, Lin SC, Chang CP, Rosenfeld MG, Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth [see comments]. Nature. 1992 Dec 24-31;360(6406):765-8
1J:57673 Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisua-Belmonte JC, Rosenfeld MG, Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999 Sep 16;401(6750):279-82
2J:17223 Lin SC, Li S, Drolet DW, Rosenfeld MG, Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope. Development. 1994 Mar;120(3):515-22
4J:13404 Lin SC, Lin CR, Gukovsky I, Lusis AJ, Sawchenko PE, Rosenfeld MG, Molecular basis of the little mouse phenotype and implications for cell type-specific growth [see comments]. Nature. 1993 Jul 15;364(6434):208-13
2*J:70462 Liu J, Lin C, Gleiberman A, Ohgi KA, Herman T, Huang HP, Tsai MJ, Rosenfeld MG, Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8674-9
1J:218295 Mortensen AH, Schade V, Lamonerie T, Camper SA, Deletion of OTX2 in neural ectoderm delays anterior pituitary development. Hum Mol Genet. 2015 Feb 15;24(4):939-53
2J:214133 Nantie LB, Himes AD, Getz DR, Raetzman LT, Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification. Mol Endocrinol. 2014 May;28(5):731-44
4J:114817 Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG, Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 5;125(3):593-605
7J:234328 Perez Millan MI, Brinkmeier ML, Mortensen AH, Camper SA, PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells. Elife. 2016;5
2J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
3J:194768 Prince KL, Colvin SC, Park S, Lai X, Witzmann FA, Rhodes SJ, Developmental analysis and influence of genetic background on the Lhx3 W227ter mouse model of combined pituitary hormone deficiency disease. Endocrinology. 2013 Feb;154(2):738-48
1J:82562 Pulichino AM, Vallette-Kasic S, Tsai JP, Couture C, Gauthier Y, Drouin J, Tpit determines alternate fates during pituitary cell differentiation. Genes Dev. 2003 Mar 15;17(6):738-47
3J:143958 Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carriere C, Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2481-6
2J:122509 Raetzman LT, Cai JX, Camper SA, Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 2007 Apr 15;304(2):455-66
1J:114717 Raetzman LT, Wheeler BS, Ross SA, Thomas PQ, Camper SA, Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol. 2006 Nov;20(11):2898-908
1J:12567 Rhodes SJ, Chen R, DiMattia GE, Scully KM, Kalla KA, Lin SC, Yu VC, Rosenfeld MG, A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene. Genes Dev. 1993 Jun;7(6):913-32
2J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68
1J:142649 Sajedi E, Gaston-Massuet C, Signore M, Andoniadou CL, Kelberman D, Castro S, Etchevers HC, Gerrelli D, Dattani MT, Martinez-Barbera JP, Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism. Dis Model Mech. 2008 Nov;1(4-5):241-54
1J:44644 Sheng HZ, Moriyama K, Yamashita T, Li H, Potter SS, Mahon KA, Westphal H, Multistep control of pituitary organogenesis. Science. 1997 Dec 5;278(5344):1809-12
1J:33050 Sheng HZ, Zhadanov AB, Mosinger B Jr, Fujii T, Bertuzzi S, Grinberg A, Lee EJ, Huang SP, Mahon KA, Westphal H, Specification of pituitary cell lineages by the LIM homeobox gene Lhx3. Science. 1996 May 17;272(5264):1004-7
1*J:36967 Sornson MW, Wu W, Dasen JS, Flynn SE, Norman DJ, O'Connell SM, Gukovsky I, Carriere C, Ryan AK, Miller AP, Zuo L, Gleiberman AS, Andersen B, Beamer WG, Rosenfeld MG, Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism. Nature. 1996 Nov 28;384(6607):327-33
1J:73774 Suh H, Gage PJ, Drouin J, Camper SA, Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development. 2002 Jan;129(2):329-37
3*J:34314 Szeto DP, Ryan AK, O'Connell SM, Rosenfeld MG, P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7706-10
2J:48144 Treier M, Gleiberman AS, O'Connell SM, Szeto DP, McMahon JA, McMahon AP, Rosenfeld MG, Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev. 1998 Jun 1;12(11):1691-704
1J:198684 Trowe MO, Zhao L, Weiss AC, Christoffels V, Epstein DJ, Kispert A, Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development. 2013 Jun;140(11):2299-309
3J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3*J:121427 Wang J, Scully K, Zhu X, Cai L, Zhang J, Prefontaine GG, Krones A, Ohgi KA, Zhu P, Garcia-Bassets I, Liu F, Taylor H, Lozach J, Jayes FL, Korach KS, Glass CK, Fu XD, Rosenfeld MG, Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature. 2007 Apr 19;446(7138):882-7
1J:92940 Wang W, Grimmer JF, Van De Water TR, Lufkin T, Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell. 2004 Sep;7(3):439-53
1J:166929 Wang Y, Martin JF, Bai CB, Direct and indirect requirements of Shh/Gli signaling in early pituitary development. Dev Biol. 2010 Dec 15;348(2):199-209
2J:108961 Ward RD, Stone BM, Raetzman LT, Camper SA, Cell proliferation and vascularization in mouse models of pituitary hormone deficiency. Mol Endocrinol. 2006 Jun;20(6):1378-90
2J:206319 Welcker JE, Hernandez-Miranda LR, Paul FE, Jia S, Ivanov A, Selbach M, Birchmeier C, Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013 Dec;140(24):4947-58
3*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1J:24499 Zhadanov AB, Bertuzzi S, Taira M, Dawid IB, Westphal H, Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues. Dev Dyn. 1995 Apr;202(4):354-64
2J:166872 Zhang Z, Florez S, Gutierrez-Hartmann A, Martin JF, Amendt BA, MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression. J Biol Chem. 2010 Nov 5;285(45):34718-28
6J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53

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