Gene Expression Literature Summary

• Symbol: Nppa
• Name: natriuretic peptide type A
• ID: MGI:97367

295 matching records from 295 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E5.5	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	E19.5	E20	E	P
Immunohistochemistry (section)								2		4		6		3	2	3		1	1	4		1			1				1	1	8
In situ RNA (section)	1		1	1		3	5	20	1	20	2	17	1	11	2	8		14		3	3	4	1	8		4		1		6	12
In situ RNA (whole mount)					1	5	14	44	4	12	2	4		4		3								1						6	1
In situ reporter (knock in)						1		1		1		1		2						1											1
Northern blot													1						1		1				1						11
Western blot												1								1											3
RT-PCR		1		1		3	3	22	2	13	2	8	1	13	2	8	2	8	2	6	2	3	2	6	1	6	1		1	2	78
cDNA clones																							1								3
RNase protection				1		1												1						1							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nppa  natriuretic peptide type A   (Synonyms: Anf, ANP, atrial natriuretic peptide, natriuretic peptide precursor A, Pnd)
Results	Reference
1	J:345821 Allwood MA, Edgett BA, Platt MJ, Marrow JP, Coyle-Asbil B, Holjak EJB, Nelson VL, Bangali S, Alshamali R, Jacyniak K, Klein JM, Farquharson L, Romanova N, Northrup V, Ogilvie LM, Ayoub A, Ask K, Vickaryous MK, Hare GMT, Brunt KR, Simpson JA, Novel roles of cardiac-derived erythropoietin in cardiac development and function. J Mol Cell Cardiol. 2024 Mar;188:90-104
1	J:74656 Andree B, Fleige A, Arnold HH, Brand T, Mouse Pop1 is required for muscle regeneration in adult skeletal muscle. Mol Cell Biol. 2002 Mar;22(5):1504-12
1	J:253754 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Gasser A, Messaddeq N, Dolle P, Nebigil CG, Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development. Sci Rep. 2016 May 6;6:25541
1	J:166932 Asai R, Kurihara Y, Fujisawa K, Sato T, Kawamura Y, Kokubo H, Tonami K, Nishiyama K, Uchijima Y, Miyagawa-Tomita S, Kurihara H, Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation. Development. 2010 Nov;137(22):3823-33
1*	J:252376 Baker ZN, Jett K, Boulet A, Hossain A, Cobine PA, Kim BE, El Zawily AM, Lee L, Tibbits GF, Petris MJ, Leary SC, The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart. Hum Mol Genet. 2017 Dec 1;26(23):4617-4628
2	J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9
1	J:185264 Banerjee I, Zhang J, Moore-Morris T, Lange S, Shen T, Dalton ND, Gu Y, Peterson KL, Evans SM, Chen J, Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res. 2012 Feb 3;110(3):456-64
1	J:171088 Barnes RM, Firulli BA, Vandusen NJ, Morikawa Y, Conway SJ, Cserjesi P, Vincentz JW, Firulli AB, Hand2 Loss-of-Function in Hand1-Expressing Cells Reveals Distinct Roles in Epicardial and Coronary Vessel Development. Circ Res. 2011 Apr 15;108(8):940-9
2	J:213344 Barratt KS, Glanville-Jones HC, Arkell RM, The Zic2 gene directs the formation and function of node cilia to control cardiac situs. Genesis. 2014 Jun;52(6):626-35
1	J:304446 Beckert V, Rassmann S, Kayvanjoo AH, Klausen C, Bonaguro L, Botermann DS, Krause M, Moreth K, Spielmann N, da Silva-Buttkus P, Fuchs H, Gailus-Durner V, de Angelis MH, Handler K, Ulas T, Aschenbrenner AC, Mass E, Wachten D, Creld1 regulates myocardial development and function. J Mol Cell Cardiol. 2021 Mar 24;156:45-56
1	J:221142 Beketaev I, Zhang Y, Kim EY, Yu W, Qian L, Wang J, Critical role of YY1 in cardiac morphogenesis. Dev Dyn. 2015 May;244(5):669-80
1	J:153091 Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA, Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14932-6
2	J:341993 Bernheim S, Borgel A, Le Garrec JF, Perthame E, Desgrange A, Michel C, Guillemot L, Sart S, Baroud CN, Krezel W, Raimondi F, Bonnet D, Zaffran S, Houyel L, Meilhac SM, Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells. Dev Cell. 2023 Oct 13;
1	J:180603 Bertrand AT, Renou L, Papadopoulos A, Beuvin M, Lacene E, Massart C, Ottolenghi C, Decostre V, Maron S, Schlossarek S, Cattin ME, Carrier L, Malissen M, Arimura T, Bonne G, DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death. Hum Mol Genet. 2012 Mar 1;21(5):1037-48
1*	J:276168 Bhattacharyya S, Duan J, Wang L, Li B, Bhakta M, Fernandez-Perez A, Hon GC, Munshi NV, Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition. Sci Rep. 2019 Feb 14;9(1):2106
1*	J:316441 Bohuslavova R, Skvorova L, Sedmera D, Semenza GL, Pavlinkova G, Increased susceptibility of HIF-1alpha heterozygous-null mice to cardiovascular malformations associated with maternal diabetes. J Mol Cell Cardiol. 2013 Jul;60:129-41
1	J:161903 Boogerd KJ, Wong LY, Christoffels VM, Klarenbeek M, Ruijter JM, Moorman AF, Barnett P, Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43. Cardiovasc Res. 2008 Jun 1;78(3):485-93
1	J:101738 Briegel KJ, Baldwin HS, Epstein JA, Joyner AL, Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh. Development. 2005 Jul;132(14):3305-16
1	J:334092 Broadway-Stringer S, Jiang H, Wadmore K, Hooper C, Douglas G, Steeples V, Azad AJ, Singer E, Reyat JS, Galatik F, Ehler E, Bennett P, Kalisch-Smith JI, Sparrow DB, Davies B, Djinovic-Carugo K, Gautel M, Watkins H, Gehmlich K, Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2. Cells. 2023 Feb 24;12(5)
3	J:195548 Brody MJ, Hacker TA, Patel JR, Feng L, Sadoshima J, Tevosian SG, Balijepalli RC, Moss RL, Lee Y, Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS One. 2012;7(12):e51621
1	J:83014 Bruneau BG, The developing heart and congenital heart defects: a make or break situation. Clin Genet. 2003 Apr;63(4):252-61
4	J:67359 Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG, Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Mol Cell Biol. 2001 Mar;21(5):1730-6
3	J:71845 Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG, A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell. 2001 Sep 21;106(6):709-21
1	J:98516 Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S, T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May;132(10):2475-87
1	J:178530 Cai X, Nomura-Kitabayashi A, Cai W, Yan J, Christoffels VM, Cai CL, Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2. Dev Biol. 2011 Dec 15;360(2):381-90
1*	J:152696 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ, MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86
13	J:31876 Cameron VA, Aitken GD, Ellmers LJ, Kennedy MA, Espiner EA, The sites of gene expression of atrial, brain, and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology. 1996 Mar;137(3):817-24
1	J:95385 Cao D, Wang Z, Zhang CL, Oh J, Xing W, Li S, Richardson JA, Wang DZ, Olson EN, Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol. 2005 Jan;25(1):364-76
2	J:79153 Chen F, Kook H, Milewski R, Gitler A, Lu M, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay J, Novotny J, Schwartz R, Harvey R, Mullins M, Epstein J, Hop Is an Unusual Homeobox Gene that Modulates Cardiac Development. Cell. 2002 Sep 20;110(6):713
1	J:89476 Chen H, Shi S, Acosta L, Li W, Lu J, Bao S, Chen Z, Yang Z, Schneider MD, Chien KR, Conway SJ, Yoder MC, Haneline LS, Franco D, Shou W, BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004 May;131(9):2219-31
1	J:121400 Chen JW, Zhou B, Yu QC, Shin SJ, Jiao K, Schneider MD, Baldwin HS, Bergelson JM, Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves. Circ Res. 2006 Apr 14;98(7):923-30
1	J:171873 Chen PC, Wakimoto H, Conner D, Araki T, Yuan T, Roberts A, Seidman CE, Bronson R, Neel BG, Seidman JG, Kucherlapati R, Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome-associated Sos1 mutation. J Clin Invest. 2010 Dec 1;120(12):4353-65
1	J:300948 Chen X, Liu Y, Xu C, Ba L, Liu Z, Li X, Huang J, Simpson E, Gao H, Cao D, Sheng W, Qi H, Ji H, Sanderson M, Cai CL, Li X, Yang L, Na J, Yamamura K, Liu Y, Huang G, Shou W, Sun N, QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function. Nat Commun. 2021 Jan 4;12(1):89
1	J:139946 Chen YH, Ishii M, Sucov HM, Maxson RE Jr, Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium. BMC Dev Biol. 2008;8:75
7*	J:316204 Chen Z, Xu N, Chong D, Guan S, Jiang C, Yang Z, Li C, Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
1	J:172665 Chinchilla A, Daimi H, Lozano-Velasco E, Dominguez JN, Caballero R, Delpon E, Tamargo J, Cinca J, Hove-Madsen L, Aranega AE, Franco D, PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis. Circ Cardiovasc Genet. 2011 Jun;4(3):269-79
1	J:280323 Cho E, Kang H, Kang DK, Lee Y, Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice. J Biol Chem. 2019 Mar 29;294(13):4981-4996
1*	J:133691 Choi M, Stottmann RW, Yang YP, Meyers EN, Klingensmith J, The bone morphogenetic protein antagonist noggin regulates mammalian cardiac morphogenesis. Circ Res. 2007 Feb 2;100(2):220-8
2	J:336417 Chong D, Gu Y, Zhang T, Xu Y, Bu D, Chen Z, Xu N, Li L, Zhu X, Wang H, Li Y, Zheng F, Wang D, Li P, Xu L, Hu Z, Li C, Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming. Cell Discov. 2022 Oct 11;8(1):106
7*	J:64882 Christoffels VM, Habets PE, Franco D, Campione M, de Jong F, Lamers WH, Bao ZZ, Palmer S, Biben C, Harvey RP, Moorman AF, Chamber formation and morphogenesis in the developing mammalian heart [published erratum appears in Dev Biol 2000 Sep 1;225(1):266]. Dev Biol. 2000 Jul 15;223(2):266-78
2*	J:89198 Christoffels VM, Hoogaars WM, Tessari A, Clout DE, Moorman AF, Campione M, T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn. 2004 Apr;229(4):763-70
3*	J:64020 Christoffels VM, Keijser AG, Houweling AC, Clout DE, Moorman AF, Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart. Dev Biol. 2000 Aug 15;224(2):263-74
2	J:108818 Chuva de Sousa Lopes SM, Hassink RJ, Feijen A, van Rooijen MA, Doevendans PA, Tertoolen L, Brutel de la Riviere A, Mummery CL, Patterning the heart, a template for human cardiomyocyte development. Dev Dyn. 2006 Apr 28;235(7):1994-2002
1	J:236425 Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR, Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development. Dev Biol. 2016 Oct 1;418(1):157-65
1	J:102537 Compernolle V, Brusselmans K, Franco D, Moorman A, Dewerchin M, Collen D, Carmeliet P, Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha. Cardiovasc Res. 2003 Dec 1;60(3):569-79
1*	J:177922 Costa MW, Lee S, Furtado MB, Xin L, Sparrow DB, Martinez CG, Dunwoodie SL, Kurtenbach E, Mohun T, Rosenthal N, Harvey RP, Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5. PLoS One. 2011;6(9):e24812
2	J:174203 Crippa S, Cassano M, Messina G, Galli D, Galvez BG, Curk T, Altomare C, Ronzoni F, Toelen J, Gijsbers R, Debyser Z, Janssens S, Zupan B, Zaza A, Cossu G, Sampaolesi M, miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors. J Cell Biol. 2011 Jun 27;193(7):1197-212
3	J:183869 Cui Y, Wang W, Dong N, Lou J, Srinivasan DK, Cheng W, Huang X, Liu M, Fang C, Peng J, Chen S, Wu S, Liu Z, Dong L, Zhou Y, Wu Q, Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy. Nature. 2012 Apr 12;484(7393):246-50
1	J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20
1	J:155846 de Lange FJ, Moorman AF, Anderson RH, Manner J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM, Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 2004 Sep 17;95(6):645-54
2	J:176023 del Barco Barrantes I, Coya JM, Maina F, Arthur JS, Nebreda AR, Genetic analysis of specific and redundant roles for p38alpha and p38beta MAPKs during mouse development. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12764-9
9	J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445
1	J:181488 Delgado-Olguin P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG, Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet. 2012;44(3):343-7
1	J:91438 DiCicco-Bloom E, Lelievre V, Zhou X, Rodriguez W, Tam J, Waschek JA, Embryonic expression and multifunctional actions of the natriuretic peptides and receptors in the developing nervous system. Dev Biol. 2004 Jul 1;271(1):161-75
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:88432 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD, Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 2004 Feb 25;23(4):885-96
1	J:208305 Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ, Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nat Cell Biol. 2013 Nov;15(11):1282-93
1*	J:251273 Doroudgar S, Quijada P, Konstandin M, Ilves K, Broughton K, Khalafalla FG, Casillas A, Nguyen K, Gude N, Toko H, Ornelas L, Thuerauf DJ, Glembotski CC, Sussman MA, Volkers M, S100A4 protects the myocardium against ischemic stress. J Mol Cell Cardiol. 2016 Nov;100:54-63
5	J:78579 Ellmers LJ, Knowles JW, Kim HS, Smithies O, Maeda N, Cameron VA, Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis. Am J Physiol Heart Circ Physiol. 2002 Aug;283(2):H707-14
1	J:175381 Espinoza-Lewis RA, Liu H, Sun C, Chen C, Jiao K, Chen Y, Ectopic expression of Nkx2.5 suppresses the formation of the sinoatrial node in mice. Dev Biol. 2011 Aug 15;356(2):359-69
2*	J:146147 Espinoza-Lewis RA, Yu L, He F, Liu H, Tang R, Shi J, Sun X, Martin JF, Wang D, Yang J, Chen Y, Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. Dev Biol. 2009 Mar 15;327(2):376-85
1	J:271287 Fakruddin M, Wei FY, Suzuki T, Asano K, Kaieda T, Omori A, Izumi R, Fujimura A, Kaitsuka T, Miyata K, Araki K, Oike Y, Scorrano L, Suzuki T, Tomizawa K, Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease. Cell Rep. 2018 Jan 9;22(2):482-496
2	J:307972 Farrell ET, Grimes AC, de Lange WJ, Armstrong AE, Ralphe JC, Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy. Front Physiol. 2017;8:414
1*	J:37583 Fassler R, Rohwedel J, Maltsev V, Bloch W, Lentini S, Guan K, Gullberg D, Hescheler J, Addicks K, Wobus AM, Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin. J Cell Sci. 1996 Dec;109(Pt 13):2989-99
1	J:97663 Fiore R, Rahim B, Christoffels VM, Moorman AF, Puschel AW, Inactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system. Mol Cell Biol. 2005 Mar;25(6):2310-9
1	J:46384 Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN, Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 1998 Mar;18(3):266-70
1*	J:306226 Firulli BA, George RM, Harkin J, Toolan KP, Gao H, Liu Y, Zhang W, Field LJ, Liu Y, Shou W, Payne RM, Rubart-von der Lohe M, Firulli AB, HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovasc Res. 2020 Mar 1;116(3):605-618
1	J:164028 Firulli BA, McConville DP, Byers JS 3rd, Vincentz JW, Barnes RM, Firulli AB, Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability. Dev Dyn. 2010 Oct;239(10):2748-60
2	J:311466 Firulli BA, Toolan KP, Harkin J, Millar H, Pineda S, Firulli AB, The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice. Cardiovasc Res. 2017 Dec 1;113(14):1732-1742
3	J:101349 Fischer A, Klattig J, Kneitz B, Diez H, Maier M, Holtmann B, Englert C, Gessler M, Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Mol Cell Biol. 2005 Oct;25(20):8960-70
3	J:133699 Fischer A, Steidl C, Wagner TU, Lang E, Jakob PM, Friedl P, Knobeloch KP, Gessler M, Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition. Circ Res. 2007 Mar 30;100(6):856-63
1	J:74051 Franco D, Campione M, Kelly R, Zammit PS, Buckingham M, Lamers WH, Moorman AF, Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart. Circ Res. 2000 Nov 24;87(11):984-91
1*	J:254842 Fujita J, Freire P, Coarfa C, Benham AL, Gunaratne P, Schneider MD, Dejosez M, Zwaka TP, Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell Rep. 2017 Nov 7;21(6):1562-1573
1	J:231297 Furtado MB, Wilmanns JC, Chandran A, Tonta M, Biben C, Eichenlaub M, Coleman HA, Berger S, Bouveret R, Singh R, Harvey RP, Ramialison M, Pearson JT, Parkington HC, Rosenthal NA, Costa MW, A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels. Differentiation. 2016 Jan-Mar;91(1-3):29-41
4	J:75084 Gaussin V, Van de Putte T, Mishina Y, Hanks MC, Zwijsen A, Huylebroeck D, Behringer RR, Schneider MD, Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2878-83
1	J:204450 Gavrilov S, Harvey RP, Papaioannou VE, Lack of genetic interaction between Tbx20 and Tbx3 in early mouse heart development. PLoS One. 2013;8(7):e70149
2	J:79024 Gessler M, Knobeloch K, Helisch A, Amann K, Schumacher N, Rohde E, Fischer A, Leimeister C, Mouse gridlock. No Aortic Coarctation or Deficiency, but Fatal Cardiac Defects in Hey2 -/- Mice. Curr Biol. 2002 Sep 17;12(18):1601
2	J:299975 Gharibeh L, Yamak A, Whitcomb J, Lu A, Joyal M, Komati H, Liang W, Fiset C, Nemer M, GATA6 is a regulator of sinus node development and heart rhythm. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2007322118
1*	J:71818 Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, Brook JD, Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet. 2001 Sep 1;10(18):1983-94
1	J:235368 Gomez-Del Arco P, Perdiguero E, Yunes-Leites PS, Acin-Perez R, Zeini M, Garcia-Gomez A, Sreenivasan K, Jimenez-Alcazar M, Segales J, Lopez-Maderuelo D, Ornes B, Jimenez-Borreguero LJ, D'Amato G, Enshell-Seijffers D, Morgan B, Georgopoulos K, Islam AB, Braun T, de la Pompa JL, Kim J, Enriquez JA, Ballestar E, Munoz-Canoves P, Redondo JM, The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis. Cell Metab. 2016 May 10;23(5):881-92
1	J:244992 Gomez-Velazquez M, Badia-Careaga C, Lechuga-Vieco AV, Nieto-Arellano R, Tena JJ, Rollan I, Alvarez A, Torroja C, Caceres EF, Roy AR, Galjart N, Delgado-Olguin P, Sanchez-Cabo F, Enriquez JA, Gomez-Skarmeta JL, Manzanares M, CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart. PLoS Genet. 2017 Aug;13(8):e1006985
2	J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9
1	J:292120 Guo Y, Sui JY, Kim K, Zhang Z, Qu XA, Nam YJ, Willette RN, Barnett JV, Knollmann BC, Force T, Lal H, Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling. Circulation. 2019 Nov 26;140(22):1820-1833
1	J:132079 Gustafson-Wagner EA, Sinn HW, Chen YL, Wang DZ, Reiter RS, Lin JL, Yang B, Williamson RA, Chen J, Lin CI, Lin JJ, Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2680-92
2	J:317602 Haaning AM, Quinn ME, Ware SM, Heterotaxy-spectrum heart defects in Zic3 hypomorphic mice. Pediatr Res. 2013 Nov;74(5):494-502
5	J:76656 Habets PE, Moorman AF, Clout DE, Van Roon MA, Lingbeek M, Van Lohuizen M, Campione M, Christoffels VM, Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev. 2002 May 15;16(10):1234-46
16	J:335098 Han F, Yang B, Chen Y, Liu L, Cheng X, Huang J, Zhou K, Zhang D, Xu E, Lai M, Lv B, Cheng H, Zhang H, Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription. Angiogenesis. 2023 May;26(2):217-232
1	J:162637 Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP, Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010 Jul 1;466(7302):62-7
1*	J:93610 Harrelson Z, Kelly RG, Goldin SN, Gibson-Brown JJ, Bollag RJ, Silver LM, Papaioannou VE, Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development. 2004 Oct;131(20):5041-52
1	J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61
1	J:261899 Hasten E, McDonald-McGinn DM, Crowley TB, Zackai E, Emanuel BS, Morrow BE, Racedo SE, Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome. Hum Mol Genet. 2018 Jun 1;27(11):1847-1857
1	J:122471 Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP, Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F, Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Mol Genet Metab. 2007 Jul;91(3):285-93
2	J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15
1	J:96392 Herron BJ, Rao C, Liu S, Laprade L, Richardson JA, Olivieri E, Semsarian C, Millar SE, Stubbs L, Beier DR, A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice. Hum Mol Genet. 2005 Mar 1;14(5):667-77
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
4	J:121230 Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM, Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev. 2007 May 1;21(9):1098-112
1	J:91321 Hoogaars WM, Tessari A, Moorman AF, de Boer PA, Hagoort J, Soufan AT, Campione M, Christoffels VM, The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart. Cardiovasc Res. 2004 Jun 1;62(3):489-99
5	J:278530 Horsthuis T, Houweling AC, Habets PE, de Lange FJ, el Azzouzi H, Clout DE, Moorman AF, Christoffels VM, Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008 Apr 11;102(7):849-59
2*	J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954
1*	J:92209 Huang F, Wagner M, Siddiqui MA, Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72
1	J:212665 Huang ZP, Young Seok H, Zhou B, Chen J, Chen JF, Tao Y, Pu WT, Wang DZ, CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16;110(6):818-30
1*	J:333714 Huynh H, Zhu S, Lee S, Bao Y, Pang J, Nguyen A, Gu Y, Chen C, Ouyang K, Evans SM, Fang X, DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 Feb;175:44-48
1	J:109474 Ilagan R, Abu-Issa R, Brown D, Yang YP, Jiao K, Schwartz RJ, Klingensmith J, Meyers EN, Fgf8 is required for anterior heart field development. Development. 2006 Jun;133(12):2435-45
1	J:222220 Iso T, Maeda K, Hanaoka H, Suga T, Goto K, Syamsunarno MR, Hishiki T, Nagahata Y, Matsui H, Arai M, Yamaguchi A, Abumrad NA, Sano M, Suematsu M, Endo K, Hotamisligil GS, Kurabayashi M, Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle. Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2549-57
1	J:149886 Itoh F, Itoh S, Carvalho RL, Adachi T, Ema M, Goumans MJ, Larsson J, Karlsson S, Takahashi S, Mummery CL, Dijke PT, Kato M, Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation. Lab Invest. 2009 Jul;89(7):800-10
2*	J:77810 Iulianella A, Lohnes D, Chimeric analysis of retinoic acid receptor function during cardiac looping. Dev Biol. 2002 Jul 1;247(1):62-75
1*	J:107401 Jadrich JL, O'connor MB, Coucouvanis E, The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development. 2006 Apr;133(8):1529-41
1	J:166306 Ji YR, Kim MO, Kim SH, Yu DH, Shin MJ, Kim HJ, Yuh HS, Bae KB, Kim JY, Park HD, Lee SG, Hyun BH, Ryoo ZY, Effects of regulator of G protein signaling 19 (RGS19) on heart development and function. J Biol Chem. 2010 Sep 10;285(37):28627-34
1	J:103761 Kaneko-Oshikawa C, Nakagawa T, Yamada M, Yoshikawa H, Matsumoto M, Yada M, Hatakeyama S, Nakayama K, Nakayama KI, Mammalian E4 is required for cardiac development and maintenance of the nervous system. Mol Cell Biol. 2005 Dec;25(24):10953-64
1	J:343799 Katano W, Mori S, Sasaki S, Tajika Y, Tomita K, Takeuchi JK, Koshiba-Takeuchi K, Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes. Development. 2023 Dec 15;150(24):dev201913
1*	J:161758 Kiefer SM, Robbins L, Barina A, Zhang Z, Rauchman M, SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes. Hum Mutat. 2008 Sep;29(9):1133-40
1	J:75968 Koga H, Kaji Y, Nishii K, Shirai M, Tomotsune D, Osugi T, Sawada A, Kim JY, Hara J, Miwa T, Yamauchi-Takihara K, Shibata Y, Takihara Y, Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy. Lab Invest. 2002 Apr;82(4):375-85
4	J:133798 Koibuchi N, Chin MT, CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression. Circ Res. 2007 Mar 30;100(6):850-5
1	J:119923 Kokubo H, Tomita-Miyagawa S, Hamada Y, Saga Y, Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2. Development. 2007 Feb;134(4):747-55
1	J:80766 Komatsu Y, Shibuya H, Takeda N, Ninomiya-Tsuji J, Yasui T, Miyado K, Sekimoto T, Ueno N, Matsumoto K, Yamada G, Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis. Mech Dev. 2002 Dec;119 Suppl 1(2):239-49
4	J:152142 Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, Bruneau BG, Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature. 2009 Sep 3;461(7260):95-8
2	J:105332 Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG, Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet. 2006 Feb;38(2):175-183
1	J:170885 Kratsios P, Catela C, Salimova E, Huth M, Berno V, Rosenthal N, Mourkioti F, Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circ Res. 2010 Feb 19;106(3):559-72
2	J:40144 Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS , Soudais C , Leiden JM, GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes Dev. 1997 Apr 15;11(8):1048-60
3*	J:86837 Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K, NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. EMBO J. 2003 Dec 1;22(23):6310-21
1*	J:175663 Laforest B, Andelfinger G, Nemer M, Loss of Gata5 in mice leads to bicuspid aortic valve. J Clin Invest. 2011 Jul 1;121(7):2876-87
1*	J:178176 Laforest B, Nemer M, GATA5 interacts with GATA4 and GATA6 in outflow tract development. Dev Biol. 2011 Oct 15;358(2):368-78
3	J:175025 Lai D, Liu X, Forrai A, Wolstein O, Michalicek J, Ahmed I, Garratt AN, Birchmeier C, Zhou M, Hartley L, Robb L, Feneley MP, Fatkin D, Harvey RP, Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium. Circ Res. 2010 Sep 17;107(6):715-27
1	J:137598 Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP, Transcriptional coactivators PGC-1{alpha} and PGC-l{beta} control overlapping programs required for perinatal maturation of the heart. Genes Dev. 2008 Jul 15;22(14):1948-61
1	J:344969 Larrasa-Alonso J, Villalba-Orero M, Marti-Gomez C, Ortiz-Sanchez P, Lopez-Olaneta MM, Rey-Martin MA, Sanchez-Cabo F, McNicoll F, Muller-McNicoll M, Garcia-Pavia P, Lara-Pezzi E, The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy. Circ Res. 2021 Sep 3;129(6):669-683
1	J:95803 Lavine KJ, Yu K, White AC, Zhang X, Smith C, Partanen J, Ornitz DM, Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev Cell. 2005 Jan;8(1):85-95
1	J:316188 Lee MJ, Kim DE, Zakrzewska A, Yoo YD, Kim SH, Kim ST, Seo JW, Lee YS, Dorn GW 2nd, Oh U, Kim BY, Kwon YT, Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes. J Biol Chem. 2012 Jul 6;287(28):24043-52
1	J:180125 Lee S, Lee JW, Lee SK, UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program. Dev Cell. 2012 Jan 17;22(1):25-37
2	J:63359 Lee Y, Song AJ, Baker R, Micales B, Conway SJ, Lyons GE, Jumonji, a nuclear protein that is necessary for normal heart development [see comments]. Circ Res. 2000 May 12;86(9):932-8
1	J:177567 Li D, Liu Y, Maruyama M, Zhu W, Chen H, Zhang W, Reuter S, Lin SF, Haneline LS, Field LJ, Chen PS, Shou W, Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy. Hum Mol Genet. 2011 Dec 1;20(23):4582-96
1	J:84789 Li S, Wang DZ, Wang Z, Richardson JA, Olson EN, The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9366-70
1	J:94180 Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG, Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature. 2004 Nov 4;432(7013):107-12
2	J:305040 Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Zhuang J, Wang Y, Wu X, Fan X, Pygo1 regulates pathological cardiac hypertrophy via a beta-catenin-dependent mechanism. Am J Physiol Heart Circ Physiol. 2021 Feb 26;320(4)
3	J:40724 Lin Q, Schwarz J, Bucana C, Olson EN, Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science. 1997 May 30;276(5317):1404-7
1	J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
1	J:146638 Liu N, Barbosa AC, Chapman SL, Bezprozvannaya S, Qi X, Richardson JA, Yanagisawa H, Olson EN, DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis. Development. 2009 Mar;136(6):933-42
1	J:142220 Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN, microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008 Dec 1;22(23):3242-54
1*	J:129208 Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O'Brien C, Seldin DC, The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development. Mol Cell Biol. 2008 Jan;28(1):131-9
1	J:315856 Lu D, Bao D, Dong W, Liu N, Zhang X, Gao S, Ge W, Gao X, Zhang L, Dkk3 prevents familial dilated cardiomyopathy development through Wnt pathway. Lab Invest. 2016 Feb;96(2):239-48
2	J:165329 Luna-Zurita L, Prados B, Grego-Bessa J, Luxan G, del Monte G, Benguria A, Adams RH, Perez-Pomares JM, de la Pompa JL, Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J Clin Invest. 2010 Oct 1;120(10):3493-507
2	J:238888 Luo W, Zhao X, Jin H, Tao L, Zhu J, Wang H, Hemmings BA, Yang Z, Akt1 signaling coordinates BMP signaling and beta-catenin activity to regulate second heart field progenitor development. Development. 2015 Feb 15;142(4):732-42
4	J:195070 Luxan G, Casanova JC, Martinez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-Garcia JL, Fernandez-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibanez B, Medrano C, Garcia-Pavia P, Gimeno JR,Monserrat L, Jimenez-Borreguero LJ, de la Pompa JL, Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med. 2013 Feb;19(2):193-201
2	J:104417 Ma L, Lu MF, Schwartz RJ, Martin JF, Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development. 2005 Dec;132(24):5601-11
2*	J:321209 Magli A, Schnettler E, Swanson SA, Borges L, Hoffman K, Stewart R, Thomson JA, Keirstead SA, Perlingeiro RC, Pax3 and Tbx5 specify whether PDGFRalpha+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells. Stem Cells. 2014 Aug;32(8):2072-83
4	J:138923 Manuylov NL, Manuylova E, Avdoshina V, Tevosian S, Serdin1/Lrrc10 is dispensable for mouse development. Genesis. 2008 Sep 9;46(9):441-446
3	J:213937 Matkovich SJ, Edwards JR, Grossenheider TC, de Guzman Strong C, Dorn GW 2nd, Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12264-9
2*	J:181087 Mayers CM, Wadell J, McLean K, Venere M, Malik M, Shibata T, Driggers PH, Kino T, Guo XC, Koide H, Gorivodsky M, Grinberg A, Mukhopadhyay M, Abu-Asab M, Westphal H, Segars JH, The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice. J Biol Chem. 2010 Apr 16;285(16):12344-54
2	J:94514 McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN, The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development. 2005 Jan;132(1):189-201
1	J:159348 McMullen NM, Zhang F, Pasumarthi KB, Assessment of embryonic myocardial cell differentiation using a dual fluorescent reporter system. J Cell Mol Med. 2009 Sep;13(9A):2834-42
1*	J:166534 Medioni C, Bertrand N, Mesbah K, Hudry B, Dupays L, Wolstein O, Washkowitz AJ, Papaioannou VE, Mohun TJ, Harvey RP, Zaffran S, Expression of Slit and Robo genes in the developing mouse heart. Dev Dyn. 2010 Dec;239(12):3303-11
1*	J:74121 Meeson AP, Radford N, Shelton JM, Mammen PP, DiMaio JM, Hutcheson K, Kong Y, Elterman J, Williams RS, Garry DJ, Adaptive mechanisms that preserve cardiac function in mice without myoglobin. Circ Res. 2001 Apr 13;88(7):713-20
1	J:115006 Mesbah K, Camus A, Babinet C, Barra J, Mutation in the Trapalpha/Ssr1 gene, encoding translocon-associated protein alpha, results in outflow tract morphogenetic defects. Mol Cell Biol. 2006 Oct;26(20):7760-71
2	J:155154 Mesbah K, Harrelson Z, Theveniau-Ruissy M, Papaioannou VE, Kelly RG, Tbx3 is required for outflow tract development. Circ Res. 2008 Sep 26;103(7):743-50
1	J:306706 Metais A, Lamsoul I, Melet A, Uttenweiler-Joseph S, Poincloux R, Stefanovic S, Valiere A, Gonzalez de Peredo A, Stella A, Burlet-Schiltz O, Zaffran S, Lutz PG, Moog-Lutz C, Asb2alpha-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development. Circ Res. 2018 Mar 16;122(6):e34-e48
1*	J:93830 Minamisawa S, Oshikawa J, Takeshima H, Hoshijima M, Wang Y, Chien KR, Ishikawa Y, Matsuoka R, Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun. 2004 Dec 17;325(3):852-856
1*	J:344337 Mishra A, Tavasoli M, Sokolenko S, McMaster CR, Pasumarthi KBS, Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart. iScience. 2024 Jan 19;27(1):108748
1	J:185124 Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V, Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. PLoS Genet. 2012 May;8(5):e1002690
2	J:200776 Mittal A, Pulina M, Hou SY, Astrof S, Fibronectin and integrin alpha 5 play requisite roles in cardiac morphogenesis. Dev Biol. 2013 Sep 1;381(1):73-82
2	J:40145 Molkentin JD, Lin Q, Duncan SA, Olson EN, Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. Genes Dev. 1997 APR 15;11(8):1061-1072
4	J:133688 Mommersteeg MT, Hoogaars WM, Prall OW, de Gier-de Vries C, Wiese C, Clout DE, Papaioannou VE, Brown NA, Harvey RP, Moorman AF, Christoffels VM, Molecular pathway for the localized formation of the sinoatrial node. Circ Res. 2007 Feb 16;100(3):354-62
2	J:66436 Moorman AF, Houweling AC, de Boer PA, Christoffels VM, Sensitive nonradioactive detection of mRNA in tissue sections. Novel application of the whole-mount in situ hybridization protocol. J Histochem Cytochem. 2001 Jan;49(1):1-8
1*	J:112887 Mori AD, Zhu Y, Vahora I, Nieman B, Koshiba-Takeuchi K, Davidson L, Pizard A, Seidman JG, Seidman CE, Chen XJ, Henkelman RM, Bruneau BG, Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Dev Biol. 2006 Sep 15;297(2):566-86
2	J:155265 Morikawa Y, Cserjesi P, Cardiac neural crest expression of Hand2 regulates outflow and second heart field development. Circ Res. 2008 Dec 5;103(12):1422-9
2*	J:293579 Moumne O, Chowdhurry R, Doll C, Pereira N, Hashimi M, Grindrod T, Dollar JJ, Riva A, Kasahara H, Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies. Front Cardiovasc Med. 2018;5:100
1*	J:71977 Mummenhoff J, Houweling AC, Peters T, Christoffels VM, Ruther U, Expression of Irx6 during mouse morphogenesis. Mech Dev. 2001 May;103(1-2):193-5
1	J:172692 Mysliwiec MR, Bresnick EH, Lee Y, Endothelial jarid2/jumonji is required for normal cardiac development and proper notch1 expression. J Biol Chem. 2011 May 13;286(19):17193-204
2	J:172560 Nagy II, Railo A, Rapila R, Hast T, Sormunen R, Tavi P, Rasanen J, Vainio SJ, Wnt-11 signalling controls ventricular myocardium development by patterning N-cadherin and beta-catenin expression. Cardiovasc Res. 2010 Jan 1;85(1):100-9
2	J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82
3	J:320678 Nakayama K, Emoto N, Suzuki Y, Vignon-Zellweger N, Yagi K, Hirata K, Physiological relevance of hydrolysis of atrial natriuretic peptide by endothelin-converting enzyme-1. Kobe J Med Sci. 2012 Jun 21;58(1):E12-8
1	J:172819 Nakazawa M, Uchida K, Aramaki M, Kodo K, Yamagishi C, Takahashi T, Mikoshiba K, Yamagishi H, Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field. J Mol Cell Cardiol. 2011 Jul;51(1):58-66
1	J:168140 Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y, DOT1L regulates dystrophin expression and is critical for cardiac function. Genes Dev. 2011 Feb 1;25(3):263-74
1	J:150360 Nimura K, Ura K, Shiratori H, Ikawa M, Okabe M, Schwartz RJ, Kaneda Y, A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature. 2009 Jul 9;460(7252):287-91
2	J:101311 Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ, Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. J Biol Chem. 2005 Sep 16;280(37):32531-8
1	J:154475 Nomura-Kitabayashi A, Anderson GA, Sleep G, Mena J, Karabegovic A, Karamath S, Letarte M, Puri MC, Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo. Dev Biol. 2009 Nov 1;335(1):66-77
1	J:107397 Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE, Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development. 2006 Apr;133(8):1565-73
4*	J:12566 O'Brien TX, Lee KJ, Chien KR, Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5157-61
2*	J:136004 Ogata T, Ueyama T, Isodono K, Tagawa M, Takehara N, Kawashima T, Harada K, Takahashi T, Shioi T, Matsubara H, Oh H, MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol. 2008 May;28(10):3424-36
2	J:264118 Papoutsi T, Luna-Zurita L, Prados B, Zaffran S, de la Pompa JL, Bmp2 and Notch cooperate to pattern the embryonic endocardium. Development. 2018 Jul 2;145(13):dev163378
1*	J:227272 Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC, Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13573-8
1*	J:91025 Parlakian A, Tuil D, Hamard G, Tavernier G, Hentzen D, Concordet JP, Paulin D, Li Z, Daegelen D, Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality. Mol Cell Biol. 2004 Jun;24(12):5281-9
4*	J:316724 Pedernera E, Gomora MJ, Meneses I, De Ita M, Mendez C, Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages. BMC Physiol. 2017 Aug 14;17(1):7
1	J:105371 Peng X, Kraus MS, Wei H, Shen TL, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan JL, Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest. 2006 Jan;116(1):217-27
1	J:134635 Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL, Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6638-43
1	J:230021 Peng Y, Song L, Zhao M, Harmelink C, Debenedittis P, Cui X, Wang Q, Jiao K, Critical roles of miRNA-mediated regulation of TGFbeta signalling during mouse cardiogenesis. Cardiovasc Res. 2014 Jul 15;103(2):258-67
1	J:317434 Pernot M, Jaspard-Vinassa B, Abelanet A, Rubin S, Forfar I, Jeanningros S, Cetran L, Yu MH, Balse E, Hatem S, Dufourcq P, Couffinhal T, Duplaa C, Decrease of Pdzrn3 is required for heart maturation and protects against heart failure. Sci Rep. 2022 Jan 7;12(1):8
2	J:212185 Petchey LK, Risebro CA, Vieira JM, Roberts T, Bryson JB, Greensmith L, Lythgoe MF, Riley PR, Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9515-20
1	J:137807 Phillips HM, Rhee HJ, Murdoch JN, Hildreth V, Peat JD, Anderson RH, Copp AJ, Chaudhry B, Henderson DJ, Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization. Circ Res. 2007 Jul 20;101(2):137-45
1	J:302922 Piroddi N, Pesce P, Scellini B, Manzini S, Ganzetti GS, Badi I, Menegollo M, Cora V, Tiso S, Cinquetti R, Monti L, Chiesa G, Bleyl SB, Busnelli M, Dellera F, Bruno D, Caicci F, Grimaldi A, Taramelli R, Manni L, Sacerdoti D, Tesi C, Poggesi C, Ausoni S, Acquati F, Campione M, Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction. Cardiovasc Res. 2020 Jul 1;116(8):1458-1472
1	J:311888 Prados B, Gomez-Apinaniz P, Papoutsi T, Luxan G, Zaffran S, Perez-Pomares JM, de la Pompa JL, Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity. Cell Death Dis. 2018 Mar 14;9(3):399
1*	J:308675 Prickett AR, Montibus B, Barkas N, Amante SM, Franco MM, Cowley M, Puszyk W, Shannon MF, Irving MD, Madon-Simon M, Ward A, Schulz R, Baldwin HS, Oakey RJ, Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart. Front Cell Dev Biol. 2021;9:676543
2	J:94637 Pu WT, Ishiwata T, Juraszek AL, Ma Q, Izumo S, GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Dev Biol. 2004 Nov 1;275(1):235-44
1	J:156743 Qiu Z, Cang Y, Goff SP, c-Abl tyrosine kinase regulates cardiac growth and development. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1136-41
1	J:242314 Racedo SE, Hasten E, Lin M, Devakanmalai GS, Guo T, Ozbudak EM, Cai CL, Zheng D, Morrow BE, Reduced dosage of beta-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome. PLoS Genet. 2017 Mar;13(3):e1006687
1	J:228847 Ramsbottom SA, Sharma V, Rhee HJ, Eley L, Phillips HM, Rigby HF, Dean C, Chaudhry B, Henderson DJ, Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development. PLoS Genet. 2014 Dec;10(12):e1004871
1	J:333399 Rhee S, Paik DT, Yang JY, Nagelberg D, Williams I, Tian L, Roth R, Chandy M, Ban J, Belbachir N, Kim S, Zhang H, Phansalkar R, Wong KM, King DA, Valdez C, Winn VD, Morrison AJ, Wu JC, Red-Horse K, Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction. Eur Heart J. 2021 Nov 1;42(41):4264-4276
1*	J:129349 Ribeiro I, Kawakami Y, Buscher D, Raya A, Rodriguez-Leon J, Morita M, Rodriguez Esteban C, Izpisua Belmonte JC, Tbx2 and Tbx3 regulate the dynamics of cell proliferation during heart remodeling. PLoS One. 2007;2(4):e398
2	J:144217 Risebro CA, Searles RG, Melville AA, Ehler E, Jina N, Shah S, Pallas J, Hubank M, Dillard M, Harvey NL, Schwartz RJ, Chien KR, Oliver G, Riley PR, Prox1 maintains muscle structure and growth in the developing heart. Development. 2009 Feb;136(3):495-505
3	J:116090 Risebro CA, Smart N, Dupays L, Breckenridge R, Mohun TJ, Riley PR, Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart. Development. 2006 Nov;133(22):4595-606
2	J:199136 Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE, Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet. 2013 Aug 15;22(16):3269-82
1	J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088
1*	J:187574 Rybkin II, Kim MS, Bezprozvannaya S, Qi X, Richardson JA, Plato CF, Hill JA, Bassel-Duby R, Olson EN, Regulation of atrial natriuretic peptide secretion by a novel Ras-like protein. J Cell Biol. 2007 Nov 5;179(3):527-37
1	J:186931 Saito Y, Kojima T, Takahashi N, Mab21l2 is essential for embryonic heart and liver development. PLoS One. 2012;7(3):e32991
1	J:317550 Sakamoto T, Matsuura TR, Wan S, Ryba DM, Kim JU, Won KJ, Lai L, Petucci C, Petrenko N, Musunuru K, Vega RB, Kelly DP, A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation. Circ Res. 2020 Jun 5;126(12):1685-1702
3	J:236978 Santos R, Kawauchi S, Jacobs RE, Lopez-Burks ME, Choi H, Wikenheiser J, Hallgrimsson B, Jamniczky HA, Fraser SE, Lander AD, Calof AL, Conditional Creation and Rescue of Nipbl-Deficiency in Mice Reveals Multiple Determinants of Risk for Congenital Heart Defects. PLoS Biol. 2016 Sep;14(9):e2000197
2	J:153212 Schmidt H, Stonkute A, Juttner R, Koesling D, Friebe A, Rathjen FG, C-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16847-52
6	J:164834 Scott NJ, Ellmers LJ, Lainchbury JG, Maeda N, Smithies O, Richards AM, Cameron VA, Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development. Biochim Biophys Acta. 2009 Dec;1792(12):1175-84
2	J:235687 Sergeeva IA, Hooijkaas IB, Ruijter JM, van der Made I, de Groot NE, van de Werken HJ, Creemers EE, Christoffels VM, Identification of a regulatory domain controlling the Nppa-Nppb gene cluster during heart development and stress. Development. 2016 Jun 15;143(12):2135-46
1*	J:85547 Shi W, Chen H, Sun J, Buckley S, Zhao J, Anderson KD, Williams RG, Warburton D, TACE is required for fetal murine cardiac development and modeling. Dev Biol. 2003 Sep 15;261(2):371-80
1	J:79152 Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN, Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell. 2002 Sep 20;110(6):725-35
2	J:78065 Shirai M, Osugi T, Koga H, Kaji Y, Takimoto E, Komuro I, Hara J, Miwa T, Yamauchi-Takihara K, Takihara Y, The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis. J Clin Invest. 2002 Jul;110(2):177-84
1	J:201868 Shpargel KB, Sengoku T, Yokoyama S, Magnuson T, UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012 Sep;8(9):e1002964
2	J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65
1	J:98806 Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A, Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707
1	J:181526 Singh R, Hoogaars WM, Barnett P, Grieskamp T, Rana MS, Buermans H, Farin HF, Petry M, Heallen T, Martin JF, Moorman AF, 't Hoen PA, Kispert A, Christoffels VM, Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. Cell Mol Life Sci. 2012 Apr;69(8):1377-89
1*	J:169971 Singh R, Horsthuis T, Farin HF, Grieskamp T, Norden J, Petry M, Wakker V, Moorman AF, Christoffels VM, Kispert A, Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal. Circ Res. 2009 Aug 28;105(5):442-52
1	J:305418 Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ, The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol. 2016 Aug 15;416(2):373-88
1	J:140299 Song L, Yan W, Chen X, Deng CX, Wang Q, Jiao K, Myocardial smad4 is essential for cardiogenesis in mouse embryos. Circ Res. 2007 Aug 3;101(3):277-85
4*	J:36847 Soonpaa MH, Kim KK, Pajak L, Franklin M, Field LJ, Cardiomyocyte DNA synthesis and binucleation during murine development. Am J Physiol. 1996 Nov;271(5 Pt 2):H2183-9
1	J:241230 Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE, Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. Am J Physiol Heart Circ Physiol. 2017 Apr 01;312(4):H768-H780
1	J:40768 Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN, Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND [see comments] [published erratum appears in Nat Genet 1997 Aug;16(4):410]. Nat Genet. 1997 Jun;16(2):154-60
3	J:132583 Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP, Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell. 2008 Feb;14(2):298-311
3	J:302497 Stefanovic S, Laforest B, Desvignes JP, Lescroart F, Argiro L, Maurel-Zaffran C, Salgado D, Plaindoux E, De Bono C, Pazur K, Theveniau-Ruissy M, Beroud C, Puceat M, Gavalas A, Kelly RG, Zaffran S, Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation. Elife. 2020 Aug 17;9:e55124
3	J:98489 Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, Solloway MJ, McCulley DJ, Leimena C, Preis JI, Dunwoodie SL, Elliott DE, Prall OW, Black BL, Fatkin D, Harvey RP, Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
1*	J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034
1	J:63121 Svensson EC, Huggins GS, Lin H, Clendenin C, Jiang F, Tufts R, Dardik FB, Leiden JM, A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Nat Genet. 2000 Jul;25(3):353-6
1*	J:320213 Taha MF, Javeri A, The expression of NPPA splice variants during mouse cardiac development. DNA Cell Biol. 2015 Jan;34(1):19-28
1	J:277548 Takahara S, Inoue SI, Miyagawa-Tomita S, Matsuura K, Nakashima Y, Niihori T, Matsubara Y, Saiki Y, Aoki Y, New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to beta-adrenergic stimulation-induced cardiac fibrosis. EBioMedicine. 2019 Apr;42:43-53
1*	J:205662 Takeuchi JK, Lou X, Alexander JM, Sugizaki H, Delgado-Olguin P, Holloway AK, Mori AD, Wylie JN, Munson C, Zhu Y, Zhou YQ, Yeh RF, Henkelman RM, Harvey RP, Metzger D, Chambon P, Stainier DY, Pollard KS, Scott IC, Bruneau BG, Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun. 2011;2:187
1	J:101739 Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG, Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development. 2005 May;132(10):2463-74
2*	J:87041 Takeuchi JK, Ohgi M, Koshiba-Takeuchi K, Shiratori H, Sakaki I, Ogura K, Saijoh Y, Ogura T, Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis. Development. 2003 Dec;130(24):5953-64
3	J:336298 Taliani V, Buonaiuto G, Desideri F, Setti A, Santini T, Galfre S, Schirone L, Mariani D, Frati G, Valenti V, Sciarretta S, Perlas E, Nicoletti C, Musaro A, Ballarino M, The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart. Elife. 2023 Mar 6;12
2*	J:52597 Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S, The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 1999 Mar;126(6):1269-80
1	J:69976 Tanaka M, Schinke M, Liao HS, Yamasaki N, Izumo S, Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx. Mol Cell Biol. 2001 Jul;21(13):4391-8
1*	J:61335 Tanaka M, Yamasaki N, Izumo S, Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting. Mol Cell Biol. 2000 Apr;20(8):2874-9
1	J:307814 Tannous C, Deloux R, Karoui A, Mougenot N, Burkin D, Blanc J, Coletti D, Lavery G, Li Z, Mericskay M, NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging. Int J Mol Sci. 2021 Mar 29;22(7)
1	J:147648 Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M, Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs. Circ Res. 2008 Apr 11;102(7):813-22
1	J:62879 Tevosian SG, Deconinck AE, Tanaka M, Schinke M, Litovsky SH, Izumo S, Fujiwara Y, Orkin SH, FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium. Cell. 2000 Jun 23;101(7):729-39
3	J:126898 Thackaberry EA, Bedrick EJ, Goens MB, Danielson L, Lund AK, Gabaldon D, Smith SM, Walker MK, Insulin regulation in AhR-null mice: embryonic cardiac enlargement, neonatal macrosomia, and altered insulin regulation and response in pregnant and aging AhR-null females. Toxicol Sci. 2003 Dec;76(2):407-17
1	J:102644 Thattaliyath BD, Firulli BA, Firulli AB, The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene. J Mol Cell Cardiol. 2002 Oct;34(10):1335-44
3	J:212416 Thomas PS, Rajderkar S, Lane J, Mishina Y, Kaartinen V, AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity. Dev Biol. 2014 Jun 15;390(2):191-207
9	J:263128 Tian X, Li Y, He L, Zhang H, Huang X, Liu Q, Pu W, Zhang L, Li Y, Zhao H, Wang Z, Zhu J, Nie Y, Hu S, Sedmera D, Zhong TP, Yu Y, Zhang L, Yan Y, Qiao Z, Wang QD, Wu SM, Pu WT, Anderson RH, Zhou B, Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun. 2017 Jul 20;8(1):87
1	J:91082 Togi K, Kawamoto T, Yamauchi R, Yoshida Y, Kita T, Tanaka M, Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart. Mol Cell Biol. 2004 Jun;24(11):4627-35
1	J:107480 Togi K, Yoshida Y, Matsumae H, Nakashima Y, Kita T, Tanaka M, Essential role of Hand2 in interventricular septum formation and trabeculation during cardiac development. Biochem Biophys Res Commun. 2006 Apr 28;343(1):144-51
1	J:121697 Trivedi CM, Luo Y, Yin Z, Zhang M, Zhu W, Wang T, Floss T, Goettlicher M, Noppinger PR, Wurst W, Ferrari VA, Abrams CS, Gruber PJ, Epstein JA, Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med. 2007 Mar;13(3):324-31
2	J:162596 Tsika RW, Ma L, Kehat I, Schramm C, Simmer G, Morgan B, Fine DM, Hanft LM, McDonald KS, Molkentin JD, Krenz M, Yang S, Ji J, TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction. J Biol Chem. 2010 Apr 30;285(18):13721-35
1	J:330184 Tuomainen T, Naumenko N, Mutikainen M, Shakirzyanova A, Sczelecki S, Estall JL, Ruas JL, Tavi P, PGC-1alpha4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes. Cells. 2022 Sep 20;11(19)
2	J:222450 Uribe V, Badia-Careaga C, Casanova JC, Dominguez JN, de la Pompa JL, Sanz-Ezquerro JJ, Arid3b is essential for second heart field cell deployment and heart patterning. Development. 2014 Nov;141(21):4168-81
1	J:175465 Urness LD, Bleyl SB, Wright TJ, Moon AM, Mansour SL, Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development. Dev Biol. 2011 Aug 15;356(2):383-97
4	J:274879 van Eif VWW, Stefanovic S, van Duijvenboden K, Bakker M, Wakker V, de Gier-de Vries C, Zaffran S, Verkerk AO, Boukens BJ, Christoffels VM, Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program. Development. 2019 Apr 25;146(8):dev173161
1	J:311813 VanDusen NJ, Casanovas J, Vincentz JW, Firulli BA, Osterwalder M, Lopez-Rios J, Zeller R, Zhou B, Grego-Bessa J, De La Pompa JL, Shou W, Firulli AB, Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium. Cell Rep. 2014 Dec 24;9(6):2071-83
1	J:208894 VanDusen NJ, Vincentz JW, Firulli BA, Howard MJ, Rubart M, Firulli AB, Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Dev Biol. 2014 Apr 15;388(2):149-58
1	J:244253 Vincentz JW, Toolan KP, Zhang W, Firulli AB, Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function. PLoS Genet. 2017 Jul;13(7):e1006922
3	J:93034 von Both I, Silvestri C, Erdemir T, Lickert H, Walls JR, Henkelman RM, Rossant J, Harvey RP, Attisano L, Wrana JL, Foxh1 is essential for development of the anterior heart field. Dev Cell. 2004 Sep;7(3):331-45
1*	J:102564 Wakimoto K, Fujimura H, Iwamoto T, Oka T, Kobayashi K, Kita S, Kudoh S, Kuro-o M, Nabeshima Y, Shigekawa M, Imai Y, Komuro I, Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes. Comp Biochem Physiol B Biochem Mol Biol. 2003 May;135(1):9-15
1	J:93182 Wang B, Weidenfeld J, Lu MM, Maika S, Kuziel WA, Morrisey EE, Tucker PW, Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation. Development. 2004 Sep;131(18):4477-87
1*	J:244948 Wang DY, Abbasi C, El-Rass S, Li JY, Dawood F, Naito K, Sharma P, Bousette N, Singh S, Backx PH, Cox B, Wen XY, Liu PP, Gramolini AO, Endoplasmic reticulum resident protein 44 (ERp44) deficiency in mice and zebrafish leads to cardiac developmental and functional defects. J Am Heart Assoc. 2014 Oct 20;3(5):e001018
3*	J:160540 Wang J, Klysik E, Sood S, Johnson RL, Wehrens XH, Martin JF, Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9753-8
1	J:125471 Wang J, Silva JP, Gustafsson CM, Rustin P, Larsson NG, Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4038-43
1	J:95332 Wang Z, Zhai W, Richardson JA, Olson EN, Meneses JJ, Firpo MT, Kang C, Skarnes WC, Tjian R, Polybromo protein BAF180 functions in mammalian cardiac chamber maturation. Genes Dev. 2004 Dec 15;18(24):3106-16
1	J:108444 Watanabe Y, Kokubo H, Miyagawa-Tomita S, Endo M, Igarashi K, Aisaki KI, Kanno J, Saga Y, Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse. Development. 2006 May;133(9):1625-34
1*	J:75953 Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ, Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Development. 2002 Apr;129(7):1705-14
1	J:111284 Weinert S, Bergmann N, Luo X, Erdmann B, Gotthardt M, M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere. J Cell Biol. 2006 May 22;173(4):559-70
1*	J:187480 Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS, The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 2012 Jun;26(6):2569-79
1	J:21482 Witte DP, Aronow BJ, Dry JK, Harmony JA, Temporally and spatially restricted expression of apolipoprotein J in the developing heart defines discrete stages of valve morphogenesis. Dev Dyn. 1994 Nov;201(3):290-6
1*	J:53885 Wu H, Lee SH, Gao J, Liu X, Iruela-Arispe ML, Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development. 1999 Aug;126(16):3597-605
1	J:326525 Wu T, Liang Z, Zhang Z, Liu C, Zhang L, Gu Y, Peterson KL, Evans SM, Fu XD, Chen J, PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle. Circulation. 2022 Feb 22;145(8):586-602
2	J:202466 Wystub K, Besser J, Bachmann A, Boettger T, Braun T, miR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart development. PLoS Genet. 2013 Sep;9(9):e1003793
1	J:187715 Xie L, Hoffmann AD, Burnicka-Turek O, Friedland-Little JM, Zhang K, Moskowitz IP, Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Dev Cell. 2012 Aug 14;23(2):280-91
1	J:121577 Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN, Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7975-80
1*	J:51595 Xu C, Liguori G, Persico MG, Adamson ED, Abrogation of the Cripto gene in mouse leads to failure of postgastrulation morphogenesis and lack of differentiation of cardiomyocytes. Development. 1999 Feb;126(3):483-94
3	J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6
2	J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95
3	J:192939 Yamak A, Temsah R, Maharsy W, Caron S, Paradis P, Aries A, Nemer M, Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts. Am J Physiol Heart Circ Physiol. 2012 Oct 15;303(8):H1057-66
2	J:250659 Ye B, Hou N, Xiao L, Xu Y, Boyer J, Xu H, Li F, APC controls asymmetric Wnt/beta-catenin signaling and cardiomyocyte proliferation gradient in the heart. J Mol Cell Cardiol. 2015 Dec;89(Pt B):287-96
1	J:142482 Yin Z, Jones GN, Towns WH 2nd, Zhang X, Abel ED, Binkley PF, Jarjoura D, Kirschner LS, Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation. 2008 Mar 18;117(11):1414-22
1	J:307538 Yonebayashi S, Tajiri K, Hara M, Saito H, Suzuki N, Sakai S, Kimura T, Sato A, Sekimoto A, Fujita S, Okamoto R, Schwartz RJ, Yoshida T, Imanaka-Yoshida K, Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C. Front Immunol. 2021;12:620541
1*	J:165929 Yoshida T, Gan Q, Franke AS, Ho R, Zhang J, Chen YE, Hayashi M, Majesky MW, Somlyo AV, Owens GK, Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. J Biol Chem. 2010 Jul 2;285(27):21175-84
1*	J:149990 Yoshimura K, Kitagawa H, Fujiki R, Tanabe M, Takezawa S, Takada I, Yamaoka I, Yonezawa M, Kondo T, Furutani Y, Yagi H, Yoshinaga S, Masuda T, Fukuda T, Yamamoto Y, Ebihara K, Li DY, Matsuoka R, Takeuchi JK, Matsumoto T, Kato S, Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9280-5
1	J:321746 Yu H, Zhang F, Yan P, Zhang S, Lou Y, Geng Z, Li Z, Zhang Y, Xu Y, Lu Y, Chen C, Wang D, Zhu W, Hu X, Wang J, Zhuang T, Zhang Y, Wu G, Liu J, Zeng C, Pu WT, Sun K, Zhang B, LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. 2021;143(20):2007-2022
1	J:211364 Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, Lu S, Chen J, Yang Z, A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice. Am J Pathol. 2014 Jul;184(7):1967-80
2	J:171037 Yuasa S, Onizuka T, Shimoji K, Ohno Y, Kageyama T, Yoon SH, Egashira T, Seki T, Hashimoto H, Nishiyama T, Kaneda R, Murata M, Hattori F, Makino S, Sano M, Ogawa S, Prall OW, Harvey RP, Fukuda K, Zac1 is an essential transcription factor for cardiac morphogenesis. Circ Res. 2010 Apr 2;106(6):1083-91
3	J:291800 Yue Y, Zong W, Li X, Li J, Zhang Y, Wu R, Liu Y, Cui J, Wang Q, Bian Y, Yu X, Liu Y, Tan G, Zhang Y, Zhao G, Zhou B, Chen L, Xiao W, Cheng H, He A, Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution. Nat Cell Biol. 2020 Mar;22(3):332-340
2	J:251389 Zakariyah AF, Rajgara RF, Veinot JP, Skerjanc IS, Burgon PG, Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit. J Mol Cell Cardiol. 2017 Apr;105:89-98
3*	J:80957 Zancanaro C, Merigo F, Mucignat-Caretta C, Cavaggioni A, Neuronal nitric oxide synthase expression in the mouse vomeronasal organ during prenatal development. Eur J Neurosci. 2002 Aug;16(4):659-64
1	J:99203 Zeisberg EM, Ma Q, Juraszek AL, Moses K, Schwartz RJ, Izumo S, Pu WT, Morphogenesis of the right ventricle requires myocardial expression of Gata4. J Clin Invest. 2005 Jun 1;115(6):1522-1531
7*	J:34665 Zeller R, Bloch KD, Williams BS, Arceci RJ, Seidman CE, Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis. Genes Dev. 1987 Sep;1(7):693-8
1	J:126044 Zhang F, Pasumarthi KB, Ultrastructural and immunocharacterization of undifferentiated myocardial cells in the developing mouse heart. J Cell Mol Med. 2007 May-Jun;11(3):552-60
1	J:311867 Zhang X, Wang Z, Xu Q, Chen Y, Liu W, Zhong T, Li H, Quan C, Zhang L, Cui CP, Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium. iScience. 2021 Oct 22;24(10):103097
6	J:279072 Zhang Z, Zhang Q, Lal H, Nam YJ, Generation of Nppa-tagBFP reporter knock-in mouse line for studying cardiac chamber specification. Genesis. 2019 Jun;57(6):e23294
1	J:97579 Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA, GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol. 2005 Apr;25(7):2622-31
2*	J:153667 Zhao Z, Ma L, Regulation of axonal development by natriuretic peptide hormones. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):18016-21
1	J:150452 Zhou B, Ma Q, Kong SW, Hu Y, Campbell PH, McGowan FX, Ackerman KG, Wu B, Zhou B, Tevosian SG, Pu WT, Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. J Clin Invest. 2009 Jun;119(6):1462-76
1	J:125110 Zhu L, Harutyunyan KG, Peng JL, Wang J, Schwartz RJ, Belmont JW, Identification of a novel role of ZIC3 in regulating cardiac development. Hum Mol Genet. 2007 Jul 15;16(14):1649-60
3	J:195854 Zhu Y, Pires KM, Whitehead KJ, Olsen CD, Wayment B, Zhang YC, Bugger H, Ilkun O, Litwin SE, Thomas G, Kozma SC, Abel ED, Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth. PLoS One. 2013;8(1):e54221
1	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110