Gene Expression Literature Summary

• Symbol: Mpl
• Name: myeloproliferative leukemia virus oncogene
• ID: MGI:97076

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E8	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E14	E14.5	E15	E15.5	E16	E16.5	E17	E18	E18.5	E	P
Immunohistochemistry (section)											1					1					1		1
In situ RNA (section)					1		2		1		1							1					1
In situ RNA (whole mount)									1
Northern blot												1		1	1		1		1	1			1
RT-PCR	1	1	2	2	1	2	1	2	2	1	4	1	2	1		1					2		3
cDNA clones																						1	1
Nuclease S1																							1
Primer Extension																							1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mpl  myeloproliferative leukemia virus oncogene   (Synonyms: CD110, c-mpl, c-mpl-I, c-mpl-II, hlb219, thrombopoietin receptor, TPO-R)
Results	Reference
10*	J:23631 Alexander WS, Dunn AR, Structure and transcription of the genomic locus encoding murine c-Mpl, a receptor for thrombopoietin. Oncogene. 1995 Feb 16;10(4):795-803
1*	J:150942 Frankel WN, Yang Y, Mahaffey CL, Beyer BJ, O'Brien TP, Szt2, a novel gene for seizure threshold in mice. Genes Brain Behav. 2009 Jul;8(5):568-76
1*	J:64178 Hart A, Melet F, Grossfeld P, Chien K, Jones C, Tunnacliffe A, Favier R, Bernstein A, Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity. 2000 Aug;13(2):167-77
10*	J:163547 Ivanova A, Wuerfel J, Zhang J, Hoffmann O, Ballmaier M, Dame C, Expression pattern of the thrombopoietin receptor (Mpl) in the murine central nervous system. BMC Dev Biol. 2010;10:77
1*	J:108699 Katsumoto T, Aikawa Y, Iwama A, Ueda S, Ichikawa H, Ochiya T, Kitabayashi I, MOZ is essential for maintenance of hematopoietic stem cells. Genes Dev. 2006 May 15;20(10):1321-30
1*	J:35594 Kieran MW, Perkins AC, Orkin SH, Zon LI, Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9126-31
2*	J:139476 Pang L, Xue HH, Szalai G, Wang X, Wang Y, Watson DK, Leonard WJ, Blobel GA, Poncz M, Maturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteins. Blood. 2006 Oct 1;108(7):2198-206
1	J:92266 Parekh V, McEwen A, Barbour V, Takahashi Y, Rehg JE, Jane SM, Cunningham JM, Defective extraembryonic angiogenesis in mice lacking LBP-1a, a member of the grainyhead family of transcription factors. Mol Cell Biol. 2004 Aug;24(16):7113-29
15*	J:124109 Petit-Cocault L, Volle-Challier C, Fleury M, Peault B, Souyri M, Dual role of Mpl receptor during the establishment of definitive hematopoiesis. Development. 2007 Aug;134(16):3031-40
1*	J:152911 Stumpo DJ, Broxmeyer HE, Ward T, Cooper S, Hangoc G, Chung YJ, Shelley WC, Richfield EK, Ray MK, Yoder MC, Aplan PD, Blackshear PJ, Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood. 2009 Sep 17;114(12):2401-10
8*	J:82323 Xie X, Chan RJ, Johnson SA, Starr M, McCarthy J, Kapur R, Yoder MC, Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. Blood. 2003 Feb 15;101(4):1329-35
1*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48