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Gene Expression Literature Summary
Symbol
Name
ID
Mgp
matrix Gla protein
MGI:96976

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10.5 E11.5 E12.5 E13.5 E14.5 E15.5 E16 E16.5 E17.5 E18 E18.5 P
Immunohistochemistry (section) 1 1 2
In situ RNA (section) 2 4 2 2 1 3 1 2 3
In situ RNA (whole mount) 1 1
Northern blot 1 1
RT-PCR 1 1 1 3 3
RNase protection 1 1 1 1 1 1 1 1
Primer Extension 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mgp  matrix Gla protein   (Synonyms: Mglap)
Results  Reference
1J:297060 DeSisto J, O'Rourke R, Jones HE, Pawlikowski B, Malek AD, Bonney S, Guimiot F, Jones KL, Siegenthaler JA, Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function. Dev Cell. 2020 Jul 6;54(1):43-59.e4
1*J:40781 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G, Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 1997 May 30;89(5):747-54
5J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57
5*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1*J:54095 Inada M, Yasui T, Nomura S, Miyake S, Deguchi K, Himeno M, Sato M, Yamagiwa H, Kimura T, Yasui N, Ochi T, Endo N, Kitamura Y, Kishimoto T, Komori T, Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90
1J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33
1J:176975 Khavandgar Z, Poirier C, Clarke CJ, Li J, Wang N, McKee MD, Hannun YA, Murshed M, A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization. J Cell Biol. 2011 Jul 25;194(2):277-89
1J:40783 Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K , Shimizu Y , Bronson RT , Gao YH , Inada M , Sato M , Okamoto R , Kitamura Y , Yoshiki S , Kishimoto T, Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997 May 30;89(5):755-64
1J:203695 Lieben L, Stockmans I, Moermans K, Carmeliet G, Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality. Bone. 2013 Nov;57(1):123-31
14*J:23373 Luo G, D'Souza R, Hogue D, Karsenty G, The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development. J Bone Miner Res. 1995 Feb;10(2):325-34
4J:38867 Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G, Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 1997 Mar 6;386(6620):78-81
2*J:308708 Martinez ME, Hernandez A, The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. Front Neurosci. 2021;15:703730
1J:246045 Marulanda J, Eimar H, McKee MD, Berkvens M, Nelea V, Roman H, Borras T, Tamimi F, Ferron M, Murshed M, Matrix Gla protein deficiency impairs nasal septum growth, causing midface hypoplasia. J Biol Chem. 2017 Jul 07;292(27):11400-11412
1J:118511 Nakamura M, Matzuk MM, Gerstmayer B, Bosio A, Lauster R, Miyachi Y, Werner S, Paus R, Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J. 2003 Mar;17(3):497-9
1*J:128588 Raefski AS, Carone BR, Kaur A, Krueger W, O'Neill MJ, Wnt pathway anomalies in developing amygdalae of Turner syndrome-like mice. J Mol Neurosci. 2007;32(2):111-9
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
3J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385
2J:126724 Yao Y, Nowak S, Yochelis A, Garfinkel A, Bostrom KI, Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development. J Biol Chem. 2007 Oct 12;282(41):30131-42

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory