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Gene Expression Literature Summary
Symbol
Name
ID
Lyn
LYN proto-oncogene, Src family tyrosine kinase
MGI:96892

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E1 E3.5 E8 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15 E16 E16.5 E17 E18.5 E20 E P
Immunohistochemistry (section) 1 1 1 1 1 1 1 1 1 1 1 1
In situ RNA (section) 1 1 1 2
In situ reporter (knock in) 1
Western blot 1 1 2
RT-PCR 1 1 1 1 1 1 2
cDNA clones 1 2 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Lyn  LYN proto-oncogene, Src family tyrosine kinase   (Synonyms: Hck-2, Yamaguchi sarcoma viral (v-yes-1) oncogene homolog)
Results  Reference
4*J:28287 Achen MG, Clauss M, Schnurch H, Risau W, The non-receptor tyrosine kinase Lyn is localised in the developing murine blood-brain barrier. Differentiation. 1995 Jul;59(1):15-24
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
2J:148253 Kao TJ, Palmesino E, Kania A, SRC family kinases are required for limb trajectory selection by spinal motor axons. J Neurosci. 2009 Apr 29;29(17):5690-700
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
2J:19199 Larsson-Blomberg L, Dzierzak E, Isolation of tyrosine kinase related genes expressed in the early hematopoietic system. FEBS Lett. 1994 Jul 11;348(2):119-25
2J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940
1J:213066 Namba T, Kibe Y, Funahashi Y, Nakamuta S, Takano T, Ueno T, Shimada A, Kozawa S, Okamoto M, Shimoda Y, Oda K, Wada Y, Masuda T, Sakakibara A, Igarashi M, Miyata T, Faivre-Sarrailh C, Takeuchi K, Kaibuchi K, Pioneering axons regulate neuronal polarization in the developing cerebral cortex. Neuron. 2014 Feb 19;81(4):814-29
1J:28731 Reith AD, Isolation and chromosomal location of Nsk1, a novel murine putative receptor tyrosine kinase. Mamm Genome. 1995 Sep;6(9):689
1J:22208 Ruiz JC, Conlon FL, Robertson EJ, Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech Dev. 1994 Dec;48(3):153-64
1J:27414 Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE, Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995 Jul 20;11(2):245-51
3*J:194960 Tai G, Hohenstein P, Davies JA, FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique. Biol Open. 2013;2:416-423
4J:70887 Umemori H, Wanaka A, Kato H, Takeuchi M, Tohyama M, Yamamoto T, Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system. Brain Res Mol Brain Res. 1992 Dec;16(3-4):303-10
12*J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory