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Gene Expression Literature Summary
Symbol
Name
ID
Krt6
keratin 6
MGI:96703

122 matching records from 122 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9 E11 E11.5 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 1 1 2 8 1 7 2 11 4 15 2 7 1 29 3 70
Immunohistochemistry (whole mount) 1 1 1 3
Northern blot 1
Western blot 3 2
RT-PCR 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Krt6  keratin 6   (Synonyms: K6, Krt-2.6, Krt2-6)
Results  Reference
1J:281201 Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R, RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. Cell Death Differ. 2019 May;26(5):877-889
1J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134
1J:284675 Bar C, Cohen I, Zhao D, Pothula V, Litskevitch A, Koseki H, Zheng D, Ezhkova E, Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression. Cell Rep. 2019 Jul 2;28(1):257-266.e5
1J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88
2J:80753 Bernot KM, Coulombe PA, McGowan KM, Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol. 2002 Nov;119(5):1137-49
1J:312416 Bhattacharjee O, Ayyangar U, Kurbet AS, Lakshmanan V, Palakodeti D, Ginhoux F, Raghavan S, Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin. Front Immunol. 2021;12:718005
1J:179810 Blanco S, Kurowski A, Nichols J, Watt FM, Benitah SA, Frye M, The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet. 2011 Dec;7(12):e1002403
1J:114702 Blanpain C, Lowry WE, Pasolli HA, Fuchs E, Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 2006 Nov 1;20(21):3022-35
1*J:168020 Boglev Y, Wilanowski T, Caddy J, Parekh V, Auden A, Darido C, Hislop NR, Cangkrama M, Ting SB, Jane SM, The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity. Dev Biol. 2011 Jan 15;349(2):512-22
2J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17
2J:233531 Cangkrama M, Darido C, Georgy SR, Partridge D, Auden A, Srivastava S, Wilanowski T, Jane SM, Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life. J Invest Dermatol. 2016 Jul;136(7):1438-48
1J:46989 Celli G, LaRochelle WJ, Mackem S, Sharp R, Merlino G, Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J. 1998 Mar 16;17(6):1642-55
1J:318638 Chen B, Wang HL, Chen R, Chen L, Yang S, Wang Y, Xue ZF, An L314Q mutation in Map3k1 gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line. Exp Anim. 2021;70(4):459-468
1J:240181 Chen LY, Yang-Yen HF, Tsai CC, Thio CL, Chuang HL, Yang LT, Shen LF, Song IW, Liu KM, Huang YT, Liu FT, Chang YJ, Chen YT, Yen JJ, Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis. J Invest Dermatol. 2017 Apr;137(4):894-904
1J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60
3*J:217209 Cottle DL, Ursino GM, Ip SC, Jones LK, Ditommaso T, Hacking DF, Mangan NE, Mellett NA, Henley KJ, Sviridov D, Nold-Petry CA, Nold MF, Meikle PJ, Kile BT, Smyth IM, Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. Hum Mol Genet. 2015 Jan 15;24(2):436-49
1*J:202224 Crish J, Conti MA, Sakai T, Adelstein RS, Egelhoff TT, Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol. 2013 Oct 1;382(1):136-48
1J:171221 Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D, Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, Yoder BK, Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development. 2011 May;138(9):1675-85
1J:223288 Curtain M, Heffner CS, Maddox DM, Gudis P, Donahue LR, Murray SA, A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice. Mamm Genome. 2015 Apr;26(3-4):173-80
1J:269851 Dainichi T, Hayden MS, Park SG, Oh H, Seeley JJ, Grinberg-Bleyer Y, Beck KM, Miyachi Y, Kabashima K, Hashimoto T, Ghosh S, PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division. Cell Rep. 2016 May 24;15(8):1615-23
1J:177724 Danussi C, Petrucco A, Wassermann B, Pivetta E, Modica TM, Belluz Ldel B, Colombatti A, Spessotto P, EMILIN1-alpha4/alpha9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation. J Cell Biol. 2011 Oct 3;195(1):131-45
1J:178952 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM, Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 2011 Nov 15;20(5):635-48
2J:259661 De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guerin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W, A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2015 Jun;22(6):1012-24
1J:105239 Den Z, Cheng X, Merched-Sauvage M, Koch PJ, Desmocollin 3 is required for pre-implantation development of the mouse embryo. J Cell Sci. 2006 Feb 1;119(Pt 3):482-9
2J:335805 Deng Z, Butt T, Arhatari BD, Darido C, Auden A, Swaroop D, Partridge DD, Haigh K, Nguyen T, Haigh JJ, Carpinelli MR, Jane SM, Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects. Dev Dyn. 2023 May;252(5):647-667
1*J:228856 DiTommaso T, Cottle DL, Pearson HB, Schluter H, Kaur P, Humbert PO, Smyth IM, Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014 Oct;10(10):e1004706
1J:108850 Djalilian AR, McGaughey D, Patel S, Seo EY, Yang C, Cheng J, Tomic M, Sinha S, Ishida-Yamamoto A, Segre JA, Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. J Clin Invest. 2006 May;116(5):1243-53
1J:77644 Dowling J, Yu QC, Fuchs E, Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival. J Cell Biol. 1996 Jul;134(2):559-72
1J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914
1J:183190 Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Gunschmann C, Sandhoff K, Niessen CM, Niemann C, TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function. J Invest Dermatol. 2012 Feb;132(2):337-45
1J:67155 Foley J, Dann P, Hong J, Cosgrove J, Dreyer B, Rimm D, Dunbar M, Philbrick W, Wysolmerski J, Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development. Development. 2001 Feb;128(4):513-25
2J:202029 Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E, Architectural niche organization by LHX2 is linked to hair follicle stem cell function. Cell Stem Cell. 2013 Sep 5;13(3):314-27
1J:301554 Fons JM, Mozaffari M, Malik D, Marshall AR, Connor S, Greene NDE, Tucker AS, Epithelial dynamics shed light on the mechanisms underlying ear canal defects. Development. 2020 Dec 14;147(23):dev194654
1J:183925 Ganuza M, Saiz-Ladera C, Canamero M, Gomez G, Schneider R, Blasco MA, Pisano D, Paramio JM, Santamaria D, Barbacid M, Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion. EMBO J. 2012 May 30;31(11):2498-510
1J:225600 Georgy SR, Cangkrama M, Srivastava S, Partridge D, Auden A, Dworkin S, McLean CA, Jane SM, Darido C, Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma. J Natl Cancer Inst. 2015 Sep;107(9)
1J:117334 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan;12(1):99-112
1*J:240055 Grond S, Radner FP, Eichmann TO, Kolb D, Grabner GF, Wolinski H, Gruber R, Hofer P, Heier C, Schauer S, Rulicke T, Hoefler G, Schmuth M, Elias PM, Lass A, Zechner R, Haemmerle G, Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. J Invest Dermatol. 2017 Feb;137(2):403-413
2J:163218 Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rheaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, Li B, Dai X, Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol. 2009 Jun 1;185(5):811-26
1J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20
1*J:97304 Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD, Perp is a p63-regulated gene essential for epithelial integrity. Cell. 2005 Mar 25;120(6):843-56
1*J:23160 Imakado S, Bickenbach JR, Bundman DS, Rothnagel JA, Attar PS, Wang XJ, Walczak VR, Wisniewski S, Pote J, Gordon JS, Heyman RA, Evans RM, Roop DR, Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function. Genes Dev. 1995 Feb 1;9(3):317-29
1J:149833 Jensen KB, Collins CA, Nascimento E, Tan DW, Frye M, Itami S, Watt FM, Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell. 2009 May 8;4(5):427-39
1J:289452 Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren RO, Fisher A, Lane R, Young GR, Kassiotis G, Kaiser WJ, Pasparakis M, Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature. 2020 Apr;580(7803):391-395
3J:286600 Kashgari G, Meinecke L, Gordon W, Ruiz B, Yang J, Ma AL, Xie Y, Ho H, Plikus MV, Nie Q, Jester JV, Andersen B, Epithelial Migration and Non-adhesive Periderm Are Required for Digit Separation during Mammalian Development. Dev Cell. 2020 Mar 23;52(6):764-778.e4
3J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82
2*J:238698 Kasparek P, Ileninova Z, Zbodakova O, Kanchev I, Benada O, Chalupsky K, Brattsand M, Beck IM, Sedlacek R, KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype. PLoS Genet. 2017 Jan;13(1):e1006566
1*J:85304 Kaufman CK, Zhou P, Pasolli HA, Rendl M, Bolotin D, Lim KC, Dai X, Alegre ML, Fuchs E, GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev. 2003 Sep 1;17(17):2108-22
1J:228858 Kist R, Watson M, Crosier M, Robinson M, Fuchs J, Reichelt J, Peters H, The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet. 2014 Oct;10(10):e1004709
1J:106064 Kobielak A, Fuchs E, Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2322-7
1J:309667 Kousa YA, Fuller E, Schutte BC, IRF6 and AP2A Interaction Regulates Epidermal Development. J Invest Dermatol. 2018 Dec;138(12):2578-2588
2J:244349 Kousa YA, Moussa D, Schutte BC, IRF6 expression in basal epithelium partially rescues Irf6 knockout mice. Dev Dyn. 2017 Sep;246(9):670-681
1J:255609 Kousa YA, Roushangar R, Patel N, Walter A, Marangoni P, Krumlauf R, Klein OD, Schutte BC, IRF6 and SPRY4 Signaling Interact in Periderm Development. J Dent Res. 2017 Oct;96(11):1306-1313
1J:218061 Krishnaswami SR, Kumar S, Ordoukhanian P, Yu BD, Fate and Plasticity of the Epidermis in Response to Congenital Activation of BRAF. J Invest Dermatol. 2015 Feb;135(2):481-9
3J:230728 Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM, A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
1J:114152 Kuraguchi M, Wang XP, Bronson RT, Rothenberg R, Ohene-Baah NY, Lund JJ, Kucherlapati M, Maas RL, Kucherlapati R, Adenomatous Polyposis Coli (APC) is required for normal development of skin and thymus. PLoS Genet. 2006;2(9):e146
1J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47
1J:277726 Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C, Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2)
1*J:203995 Lee S, Kong Y, Weatherbee SD, Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13
2J:228844 Leilei Y, Bing L, Yang L, Shaoxia W, Yuan X, Dongping W, Huahu Y, Shichen S, Guangzhou Z, Ruiyun P, Lin Z, Wenlong L, iRhom2 mutation leads to aberrant hair follicle differentiation in mice. PLoS One. 2014;9(12):e115114
1J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83
1J:274466 Li G, Ye Z, Shi C, Sun L, Han M, Zhuang Y, Xu T, Zhao S, Wu X, The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice. Sci Rep. 2017 Apr 4;7:45401
1J:316189 Lin C, Hindes A, Burns CJ, Koppel AC, Kiss A, Yin Y, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, Efimova T, Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis. J Invest Dermatol. 2013 Mar;133(3):608-617
1*J:244468 Lin MH, Hsu FF, Miner JH, Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome. J Biol Chem. 2013 Feb 08;288(6):3964-76
1J:217937 Lin MH, Miner JH, Fatty Acid transport protein 1 can compensate for Fatty Acid transport protein 4 in the developing mouse epidermis. J Invest Dermatol. 2015 Feb;135(2):462-70
1J:281366 Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL, Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nat Commun. 2019 Oct 9;10(1):4589
1J:306624 Liu F, Zhang X, Peng Y, Zhang L, Yu Y, Hua P, Zhu P, Yan X, Li Y, Zhang L, miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3. Cell Rep. 2021 Jun 8;35(10):109225
1J:154022 Lopez RG, Garcia-Silva S, Moore SJ, Bereshchenko O, Martinez-Cruz AB, Ermakova O, Kurz E, Paramio JM, Nerlov C, C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol. 2009 Oct;11(10):1181-90
1J:119922 Mailleux AA, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge JS, BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev Cell. 2007 Feb;12(2):221-34
5J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68
1*J:66533 Mazzalupo S, Coulombe PA, A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mech Dev. 2001 Jan;100(1):65-9
5*J:50471 McGowan KM, Coulombe PA, Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol. 1998 Oct 19;143(2):469-86
1J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814
1J:161749 Mill P, Lee AW, Fukata Y, Tsutsumi R, Fukata M, Keighren M, Porter RM, McKie L, Smyth I, Jackson IJ, Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet. 2009 Nov;5(11):e1000748
1*J:215938 Mlitz V, Strasser B, Jaeger K, Hermann M, Ghannadan M, Buchberger M, Alibardi L, Tschachler E, Eckhart L, Trichohyalin-like proteins have evolutionarily conserved roles in the morphogenesis of skin appendages. J Invest Dermatol. 2014 Nov;134(11):2685-92
2J:122660 Moulson CL, Lin MH, White JM, Newberry EP, Davidson NO, Miner JH, Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice. J Biol Chem. 2007 May 25;282(21):15912-20
1*J:121243 Murray SA, Oram KF, Gridley T, Multiple functions of Snail family genes during palate development in mice. Development. 2007 May;134(9):1789-97
4J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75
1J:118511 Nakamura M, Matzuk MM, Gerstmayer B, Bosio A, Lauster R, Miyachi Y, Werner S, Paus R, Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J. 2003 Mar;17(3):497-9
1J:155012 Nguyen H, Merrill BJ, Polak L, Nikolova M, Rendl M, Shaver TM, Pasolli HA, Fuchs E, Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet. 2009 Oct;41(10):1068-75
1J:207286 Nowak JA, Polak L, Pasolli HA, Fuchs E, Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 2008 Jul 3;3(1):33-43
3J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36
1J:142136 Owens P, Bazzi H, Engelking E, Han G, Christiano AM, Wang XJ, Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity. Dev Biol. 2008 Oct 1;322(1):156-66
1*J:257248 Paul BJ, Palmer K, Sharp JC, Pratt CH, Murray SA, Dunnwald M, ARHGAP29 Mutation Is Associated with Abnormal Oral Epithelial Adhesions. J Dent Res. 2017 Oct;96(11):1298-1305
1*J:311539 Paul BJ, Palmer KJ, Rhea L, Carlson M, Sharp JC, Pratt CH, Murray SA, Dunnwald M, The Mafb cleft-associated variant H131Q is not required for palatogenesis in the mouse. Dev Dyn. 2021 Oct;250(10):1463-1476
1J:309456 Pearson HB, McGlinn E, Phesse TJ, Schluter H, Srikumar A, Godde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P, The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015 Sep 17;14:169
2J:226218 Peyrard-Janvid M, Leslie EJ, Kousa YA, Smith TL, Dunnwald M, Magnusson M, Lentz BA, Unneberg P, Fransson I, Koillinen HK, Rautio J, Pegelow M, Karsten A, Basel-Vanagaite L, Gordon W, Andersen B, Svensson T, Murray JC, Cornell RA, Kere J, Schutte BC, Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development. Am J Hum Genet. 2014 Jan 2;94(1):23-32
1*J:242353 Pichery M, Huchenq A, Sandhoff R, Severino-Freire M, Zaafouri S, Opalka L, Levade T, Soldan V, Bertrand-Michel J, Lhuillier E, Serre G, Maruani A, Mazereeuw-Hautier J, Jonca N, PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
2J:201523 Ray S, Foote HP, Lechler T, beta-Catenin protects the epidermis from mechanical stresses. J Cell Biol. 2013 Jul 8;202(1):45-52
1J:192231 Rice DS, Hansen GM, Liu F, Crist MJ, Newhouse MM, Potter D, Xu N, Abuin A, Vogel PJ, Zambrowicz BP, Keratinocyte migration in the developing eyelid requires LIMK2. PLoS One. 2012;7(10):e47168
7J:215827 Richardson RJ, Hammond NL, Coulombe PA, Saloranta C, Nousiainen HO, Salonen R, Berry A, Hanley N, Headon D, Karikoski R, Dixon MJ, Periderm prevents pathological epithelial adhesions during embryogenesis. J Clin Invest. 2014 Sep 2;124(9):3891-900
1J:168262 Romano RA, Smalley K, Liu S, Sinha S, Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha. Development. 2010 May;137(9):1431-9
2J:200244 Roth W, Kumar V, Beer HD, Richter M, Wohlenberg C, Reuter U, Thiering S, Staratschek-Jox A, Hofmann A, Kreusch F, Schultze JL, Vogl T, Roth J, Reichelt J, Hausser I, Magin TM, Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci. 2012 Nov 15;125(Pt 22):5269-79
2J:58385 Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR, The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation. 1999 Oct;65(2):119-30
3J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250
1J:306807 Saito K, Michon F, Yamada A, Inuzuka H, Yamaguchi S, Fukumoto E, Yoshizaki K, Nakamura T, Arakaki M, Chiba Y, Ishikawa M, Okano H, Thesleff I, Fukumoto S, Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ. iScience. 2020 Jul 24;23(7):101329
2J:170365 Sanchis A, Bayo P, Sevilla LM, Perez P, Glucocorticoid receptor antagonizes EGFR function to regulate eyelid development. Int J Dev Biol. 2010;54(10):1473-80
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