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Gene Expression Literature Summary
Symbol
Name
ID
Krt12
keratin 12
MGI:96687

28 matching records from 28 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19.5 E20 A
In situ protein (section) 1 2 1 1 1 2 1 4 1 7 1 5 1 6 1 1 16
In situ RNA (section) 2 1 3 3 3 3 2
Northern blot 1 1
Western blot 3
RT-PCR 1 2
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Krt12  keratin 12   (Synonyms: K12, Krt1-12)
Results  Reference
1J:105284 Birger Y, Davis J, Furusawa T, Rand E, Piatigorsky J, Bustin M, A role for chromosomal protein HMGN1 in corneal maturation. Differentiation. 2006 Feb;74(1):19-29
1J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13
2J:153549 Chen Y, Carlson EC, Chen ZY, Hamik A, Jain MK, Dunwoodie SL, Yang YC, Conditional deletion of Cited2 results in defective corneal epithelial morphogenesis and maintenance. Dev Biol. 2009 Oct 1;334(1):243-52
7J:99414 Chikama T, Hayashi Y, Liu CY, Terai N, Terai K, Kao CW, Wang L, Hayashi M, Nishida T, Sanford P, Doestchman T, Kao WW, Characterization of tetracycline-inducible bitransgenic Krt12rtTA/+/tet-O-LacZ mice. Invest Ophthalmol Vis Sci. 2005 Jun;46(6):1966-72
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:136041 Gage PJ, Qian M, Wu D, Rosenberg KI, The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol. 2008 May 1;317(1):310-24
1J:196827 Hahn N, Dietz CT, Kuhl S, Vossmerbaeumer U, Kroll J, KLEIP deficiency in mice causes progressive corneal neovascular dystrophy. Invest Ophthalmol Vis Sci. 2012 May;53(6):3260-8
3J:160411 Joo JH, Kim YH, Dunn NW, Sugrue SP, Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1927-34
1J:181400 Kuracha MR, Burgess D, Siefker E, Cooper JT, Licht JD, Robinson ML, Govindarajan V, Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6887-97
9*J:91361 Kurpakus MA, Maniaci MT, Esco M, Expression of keratins K12, K4 and K14 during development of ocular surface epithelium. Curr Eye Res. 1994 Nov;13(11):805-14
6J:16837 Liu CY, Zhu G, Westerhausen-Larson A, Converse R, Kao CW, Sun TT, Kao WW, Cornea-specific expression of K12 keratin during mouse development. Curr Eye Res. 1993 Nov;12(11):963-74
1*J:58278 Lovicu FJ, Kao WW, Overbeek PA, Ectopic gland induction by lens-specific expression of keratinocyte growth factor (FGF-7) in transgenic mice. Mech Dev. 1999 Oct;88(1):43-53
3J:171535 Lu Q, Xin Y, Ye F, Foulks G, Li Q, 14-3-3{sigma} Controls Corneal Epithelium Homeostasis and Wound Healing. Invest Ophthalmol Vis Sci. 2011 Apr;52(5):2389-96
2*J:133715 Maerker D, Stenzinger A, Schreiner D, Tag C, Wimmer M, Expression of PTPIP51 during mouse eye development. Histochem Cell Biol. 2008 Mar;129(3):345-56
1J:42107 Qin P, Piechocki M, Lu S, Kurpakus MA, Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye. Dev Dyn. 1997 Aug;209(4):367-76
10*J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32
1J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78
1J:186971 Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D, DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ. 2011 May;18(5):887-96
4*J:108338 Tanifuji-Terai N, Terai K, Hayashi Y, Chikama T, Kao WW, Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):545-51
1J:91136 Tasheva ES, Ke A, Deng Y, Jun C, Takemoto LJ, Koester A, Conrad GW, Differentially expressed genes in the lens of mimecan-null mice. Mol Vis. 2004 Jun 17;10:403-16
1J:134299 Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, Tu L, Ai D, Li D, Wang J, Martin JF, Amendt BA, Liu M, Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6081-6
1J:129101 Xu X, Mannik J, Kudryavtseva E, Lin KK, Flanagan LA, Spencer J, Soto A, Wang N, Lu Z, Yu Z, Monuki ES, Andersen B, Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells. Dev Biol. 2007 Dec 15;312(2):484-500
1J:204591 Yamben IF, Rachel RA, Shatadal S, Copeland NG, Jenkins NA, Warming S, Griep AE, Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev Biol. 2013 Dec 1;384(1):41-52
3*J:65402 Yoshida N, Yoshida S, Araie M, Handa H, Nabeshima Y, Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. Mech Dev. 2000 Oct;97(1-2):27-34
6J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204
5J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93
2J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63
2J:159631 Zhang Y, Call MK, Yeh LK, Liu H, Kochel T, Wang IJ, Chu PH, Taketo MM, Jester JV, Kao WW, Liu CY, Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci. 2010 Apr 15;123(Pt 8):1285-94

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory