Gene Expression Literature Summary
|
Symbol Name ID |
Kdr
kinase insert domain protein receptor MGI:96683 |
| Age | E1.5 | E2 | E3 | E4 | E4.5 | E5 | E5.5 | E6 | E6.5 | E7 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E19.5 | E20 | E | P |
| Immunohistochemistry (section) | 2 | 18 | 14 | 26 | 11 | 40 | 6 | 34 | 2 | 16 | 5 | 26 | 7 | 17 | 3 | 23 | 2 | 13 | 2 | 10 | 2 | 9 | 2 | 17 | 1 | 1 | 11 | 45 | ||||||||||
| In situ RNA (section) | 1 | 1 | 1 | 2 | 13 | 4 | 16 | 9 | 21 | 16 | 1 | 9 | 16 | 1 | 9 | 1 | 22 | 4 | 11 | 1 | 8 | 2 | 5 | 2 | 6 | 4 | 26 | |||||||||||
| Immunohistochemistry (whole mount) | 1 | 1 | 1 | 2 | 6 | 11 | 8 | 15 | 4 | 17 | 1 | 6 | 1 | 2 | 3 | 1 | 4 | 1 | 4 | 2 | 1 | 2 | 4 | 6 | 14 | |||||||||||||
| In situ RNA (whole mount) | 1 | 2 | 13 | 6 | 14 | 2 | 18 | 2 | 9 | 1 | 1 | 3 | 2 | |||||||||||||||||||||||||
| In situ reporter (knock in) | 1 | 5 | 14 | 16 | 24 | 9 | 19 | 3 | 6 | 2 | 7 | 3 | 8 | 1 | 5 | 5 | 1 | 7 | 1 | 1 | 2 | 3 | 2 | 18 | ||||||||||||||
| Northern blot | 1 | 1 | 3 | 1 | 2 | 1 | 3 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 3 | 1 | 2 | 1 | 3 | 5 | ||||||||||||||||
| Western blot | 1 | 1 | 2 | 4 | 2 | 2 | 1 | 4 | 1 | 4 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 3 | 19 | ||||||||||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 2 | 5 | 10 | 5 | 29 | 9 | 38 | 1 | 21 | 22 | 18 | 1 | 16 | 16 | 2 | 14 | 3 | 7 | 12 | 4 | 13 | 2 | 9 | 57 | ||||||||||
| cDNA clones | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | |||||||||||||||||||||||||||||
| RNase protection | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | ||||||||||||||||||||||||||||||
| Primer Extension | 1 |
| Kdr kinase insert domain protein receptor (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2) | |
| Results | Reference |
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| 4 | J:329888 Cioffi S, Flore G, Martucciello S, Bilio M, Turturo MG, Illingworth E, VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome. Life Sci Alliance. 2022 Dec;5(12):e202101308 |
| 2 | J:184511 Cohen ED, Miller MF, Wang Z, Moon RT, Morrisey EE, Wnt5a and Wnt11 are essential for second heart field progenitor development. Development. 2012 Jun;139(11):1931-40 |
| 2 | J:135052 Cohen TV, Kosti O, Stewart CL, The nuclear envelope protein MAN1 regulates TGFbeta signaling and vasculogenesis in the embryonic yolk sac. Development. 2007 Apr;134(7):1385-95 |
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| 2* | J:67305 Colnot CI, Helms JA, A molecular analysis of matrix remodeling and angiogenesis during long bone development. Mech Dev. 2001 Feb;100(2):245-50 |
| 1 | J:77480 Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P, Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat Med. 2002 Jul;8(7):702-10 |
| 1 | J:169692 Copeland JN, Feng Y, Neradugomma NK, Fields PE, Vivian JL, Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac. BMC Dev Biol. 2011;11:12 |
| 1 | J:163848 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E, The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell. 2010 Jun 15;18(6):938-49 |
| 1 | J:199496 Cornett B, Snowball J, Varisco BM, Lang R, Whitsett J, Sinner D, Wntless is required for peripheral lung differentiation and pulmonary vascular development. Dev Biol. 2013 Jul 1;379(1):38-52 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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