Gene Expression Literature Summary

• Symbol: Jak2
• Name: Janus kinase 2
• ID: MGI:96629

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2.5	E3	E3.5	E4	E4.5	E5.5	E8	E8.5	E9.5	E10	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E16	E17.5	E18.5	E19	E	P
Immunohistochemistry (section)		1																				1				1
In situ RNA (section)												1							1
Immunohistochemistry (whole mount)	1	1	1		1		1																			1
Northern blot																									1	1
Western blot																2						1	1	1		2
RT-PCR	1	1	2	1	1	1	2	1	1				1	1	1				1	1	1	1		1	1	5
cDNA clones										1	1	1					1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Jak2  Janus kinase 2   (Synonyms: C81284)
Results	Reference
6	J:219394 Boroviak T, Loos R, Bertone P, Smith A, Nichols J, The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification. Nat Cell Biol. 2014 Jun;16(6):516-28
1	J:141453 Cheng J, Kang X, Zhang S, Yeh ET, SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell. 2007 Nov 2;131(3):584-95
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:112700 Frenzel K, Wallace TA, McDoom I, Xiao HD, Capecchi MR, Bernstein KE, Sayeski PP, A functional Jak2 tyrosine kinase domain is essential for mouse development. Exp Cell Res. 2006 Sep 10;312(15):2735-44
2*	J:3319 Gilardi-Hebenstreit P, Nieto MA, Frain M, Mattei MG, Chestier A, Wilkinson DG, Charnay P, An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain [published erratum appears in Oncogene 1993 Apr;8(4):1103]. Oncogene. 1992 Dec;7(12):2499-506
2	J:19806 Harpur AG, Andres AC, Ziemiecki A, Aston RR, Wilks AF, JAK2, a third member of the JAK family of protein tyrosine kinases. Oncogene. 1992 Jul;7(7):1347-53
8*	J:257563 Huang K, Wang Y, Zhang T, He M, Sun G, Wen J, Yan H, Cai H, Yong C, Xia G, Wang C, JAK signaling regulates germline cyst breakdown and primordial follicle formation in mice. Biol Open. 2018 Jan 17;7(1):bio029470
1	J:310414 Hung CH, Lee TL, Huang AY, Yang KC, Shyu YC, Wen SC, Lu MJ, Yuan S, Shen CJ, A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis. Int J Mol Sci. 2021 Jul 27;22(15)
1*	J:220728 Ishikawa Y, Maeda M, Pasham M, Aguet F, Tacheva-Grigorova SK, Masuda T, Yi H, Lee SU, Xu J, Teruya-Feldstein J, Ericsson M, Mullally A, Heuser J, Kirchhausen T, Maeda T, Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology. Haematologica. 2015 Apr;100(4):439-51
12	J:91003 Ito M, Nakasato M, Suzuki T, Sakai S, Nagata M, Aoki F, Localization of janus kinase 2 to the nuclei of mature oocytes and early cleavage stage mouse embryos. Biol Reprod. 2004 Jul;71(1):89-96
1	J:327072 Kim WK, Olson AW, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff R, You S, Sun Z, Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes. Nat Commun. 2022 Jul 28;13(1):4364
1	J:92299 Krempler A, Qi Y, Triplett AA, Zhu J, Rui H, Wagner KU, Generation of a conditional knockout allele for the Janus kinase 2 (Jak2) gene in mice. Genesis. 2004 Sep;40(1):52-7
2	J:19199 Larsson-Blomberg L, Dzierzak E, Isolation of tyrosine kinase related genes expressed in the early hematopoietic system. FEBS Lett. 1994 Jul 11;348(2):119-25
2*	J:324243 Lei Z, Liu W, Nie Y, Yang Y, Chen G, Huang L, Wu H, Lei Y, Chen L, Hu Q, Rong H, Yu S, Song Q, Tong F, Guo J, EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice. Front Immunol. 2022;13:843378
3	J:47299 Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, Vanin EF, Bodner S, Colamonici OR, van Deursen JM, Grosveld G, Ihle JN, Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 1998 May 1;93(3):385-95
1	J:22208 Ruiz JC, Conlon FL, Robertson EJ, Identification of novel protein kinases expressed in the myocardium of the developing mouse heart. Mech Dev. 1994 Dec;48(3):153-64
1	J:27414 Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE, Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995 Jul 20;11(2):245-51
1*	J:190584 Zhou C, Baltz JM, JAK2 mediates the acute response to decreased cell volume in mouse preimplantation embryos by activating NHE1. J Cell Physiol. 2013 Feb;228(2):428-38