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Gene Expression Literature Summary
Symbol
Name
ID
Gna12
guanine nucleotide binding protein, alpha 12
MGI:95767

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3.5 E4 E6.5 E7.5 E8.5 E9.5 E10 E10.5 E11.5 E14.5 E15.5 E16.5 E18.5 E P
In situ RNA (section) 1 1 1
Immunohistochemistry (whole mount) 1 1
Northern blot 1 1 1 1 2
Western blot 2
RT-PCR 1 1 1 1 1 1 1 1 1 1 1 1 3
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Gna12  guanine nucleotide binding protein, alpha 12   (Synonyms: Galpha12)
Results  Reference
3J:77728 Gu JL, Muller S, Mancino V, Offermanns S, Simon MI, Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9352-7
3*J:43154 Jho EH, Malbon CC, Galpha12 and Galpha13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid. J Biol Chem. 1997 Sep 26;272(39):24461-7
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:132671 Moers A, Nurnberg A, Goebbels S, Wettschureck N, Offermanns S, Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Mol Cell Biol. 2008 Mar;28(5):1480-8
3J:50566 Offermanns S, Mancino V, Revel JP, Simon MI, Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science. 1997 Jan 24;275(5299):533-6
2*J:98850 Prescott K, Ivins S, Hubank M, Lindsay E, Baldini A, Scambler P, Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome. Hum Genet. 2005 May;116(6):486-96
5J:27182 Rambhatla L, Patel B, Dhanasekaran N, Latham KE, Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach. Mol Reprod Dev. 1995 Jul;41(3):314-24
5*J:34526 Williams CJ, Schultz RM, Kopf GS, G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
4*J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory