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Gene Expression Literature Summary
Symbol
Name
ID
Fbn1
fibrillin 1
MGI:95489

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E6.5 E8.5 E9 E10.5 E12 E12.5 E13.5 E14.5 E15 E16.5 E17.5 E18.5 A
In situ protein (section) 1 3 1 1 1 2
In situ RNA (section) 1 1 1 1 4 1 2 1
In situ RNA (whole mount) 1 1 3 1
Northern blot 2 3
Western blot 1 1
RT-PCR 1 1 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Fbn1  fibrillin 1   (Synonyms: Fib-1)
Results  Reference
6J:70592 Arteaga-Solis E, Gayraud B, Lee SY, Shum L, Sakai L, Ramirez F, Regulation of limb patterning by extracellular microfibrils. J Cell Biol. 2001 Jul 23;154(2):275-81
1*J:174611 Azhar M, Brown K, Gard C, Chen H, Rajan S, Elliott DA, Stevens MV, Camenisch TD, Conway SJ, Doetschman T, Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn. 2011 Jul 20;
2*J:135507 Bayle J, Fitch J, Jacobsen K, Kumar R, Lafyatis R, Lemaire R, Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis. J Invest Dermatol. 2008 Apr;128(4):871-81
1*J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
2J:190996 d'Amaro R, Scheidegger R, Blumer S, Pazera P, Katsaros C, Graf D, Chiquet M, Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis. Front Physiol. 2012;3:377
2J:18222 Davis EC, Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta. J Cell Sci. 1994 Mar;107(Pt 3):727-36
2J:114987 Ge G, Greenspan DS, BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein. J Cell Biol. 2006 Oct 9;175(1):111-20
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1*J:161299 Ito Y, Toriuchi N, Yoshitaka T, Ueno-Kudoh H, Sato T, Yokoyama S, Nishida K, Akimoto T, Takahashi M, Miyaki S, Asahara H, The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10538-42
1J:179089 Jaffe M, Sesti C, Washington IM, Du L, Dronadula N, Chin MT, Stolz DB, Davis EC, Dichek DA, Transforming Growth Factor-beta Signaling in Myogenic Cells Regulates Vascular Morphogenesis, Differentiation, and Matrix Synthesis. Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):e1-e11
2J:160094 Lemaire R, Farina G, Bayle J, Dimarzio M, Pendergrass SA, Milano A, Whitfield ML, Lafyatis R, Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome. J Invest Dermatol. 2010 Jun;130(6):1514-23
2*J:82234 Samuel CS, Sakai LY, Amento EP, Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin. Arch Biochem Biophys. 2003 Mar 1;411(1):47-55
1J:188834 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD Jr, Dedhar S, Parmacek MS, Gerszten RE, Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 2;109(6):616-28
3J:62831 Shipley JM, Mecham RP, Maus E, Bonadio J, Rosenbloom J, McCarthy RT, Baumann ML, Frankfater C, Segade F, Shapiro SD, Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development. Mol Cell Biol. 2000 Jul;20(13):4879-87
1J:132011 Sun J, Chen H, Chen C, Whitsett JA, Mishina Y, Bringas P Jr, Ma JC, Warburton D, Shi W, Prenatal lung epithelial cell-specific abrogation of alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol. 2008 Mar;172(3):571-82
2J:160041 Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene DR, Sengle G, Sakai LY, Sekiguchi K, ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J Biol Chem. 2010 Feb 12;285(7):4870-82
1J:139011 Wilkinson GA, Schittny JC, Reinhardt DP, Klein R, Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Dev Dyn. 2008 Aug;237(8):2220-34
2*J:96550 Williams TM, Williams ME, Kuick R, Misek D, McDonagh K, Hanash S, Innis JW, Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol. 2005 Mar 15;279(2):462-80
4J:22526 Yin W, Smiley E, Germiller J, Sanguineti C, Lawton T, Pereira L, Ramirez F, Bonadio J, Primary structure and developmental expression of Fbn-1, the mouse fibrillin gene. J Biol Chem. 1995 Jan 27;270(4):1798-806
3J:25216 Zhang H, Hu W, Ramirez F, Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils. J Cell Biol. 1995 May;129(4):1165-76

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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory