|
Symbol Name ID |
Numbl
numb-like MGI:894702 |
| Age | E8.5 | E9.5 | E10.5 | E11.5 | E12 | E12.5 | E15.5 | E16.5 | E | A |
| In situ protein (section) | 1 | 1 | 1 | 2 | 1 | |||||
| In situ RNA (section) | 1 | 1 | 1 | 1 | 1 | 1 | 3 | |||
| In situ RNA (whole mount) | 1 | |||||||||
| In situ reporter (knock in) | 1 | |||||||||
| Northern blot | 1 | |||||||||
| Western blot | 1 | 1 | ||||||||
| cDNA clones | 1 | |||||||||
| RNase protection | 1 | 1 |
| Numbl numb-like (Synonyms: nbl) | |
| Results | Reference |
| 2* | J:58382 Dho SE, French MB, Woods SA, McGlade CJ, Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain. J Biol Chem. 1999 Nov 12;274(46):33097-104 |
| 2* | J:73778 Estivill-Torrus G, Pearson H, van Heyningen V, Price DJ, Rashbass P, Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors. Development. 2002 Jan;129(2):455-66 |
| 3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
| 3 | J:182904 Moran TB, Goldberg LB, Serviss SL, Raetzman LT, Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol. 2011 Jan;25(1):117-27 |
| 2 | J:92098 Petersen PH, Zou K, Krauss S, Zhong W, Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci. 2004 Aug;7(8):803-11 |
| 2 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
| 1 | J:73266 Rice D S, Northcutt G M, Kurschner C, The Lnx family proteins function as molecular scaffolds for Numb family proteins. Mol Cell Neurosci. 2001 Nov;18(5):525-40 |
| 8* | J:41027 Zhong W, Jiang MM, Weinmaster G, Jan LY, Jan YN, Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development. 1997 May;124(10):1887-97 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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