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Gene Expression Literature Summary
Symbol
Name
ID
Dgcr2
DiGeorge syndrome critical region gene 2
MGI:892866

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9 E9.5 E10 E10.5 E11.5 E12 E13.5 E14 E14.5 E15 E15.5 E16 E17.5 E18 E18.5 E P
In situ RNA (section) 1 1 1 1 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1
Northern blot 1 1 1 1
RT-PCR 1 1 2 1 6 1 2 1 1 2 1 1 2 1 1 1 1 5
cDNA clones 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dgcr2  DiGeorge syndrome critical region gene 2   (Synonyms: 9930034O06Rik, Dgcr2, Dgsc, DGS-C, Idd, Lan, Sez12)
Results  Reference
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
9*J:45569 Funke B, Saint-Jore B, Puech A, Sirotkin H, Edelmann L, Carlson C, Raft S, Pandita RK, Kucherlapati R, Skoultchi A, Morrow BE, Characterization and mutation analysis of goosecoid-like (GSCL), a homeodomain-containing gene that maps to the critical region for VCFS/DGS on 22q11. Genomics. 1997 Dec 15;46(3):364-72
1*J:38193 Galili N, Baldwin HS, Lund J, Reeves R, Gong W, Wang Z, Roe BA, Emanuel BS, Nayak S, Mickanin C, Budarf ML, Buck CA, A region of mouse chromosome 16 is syntenic to the DiGeorge, velocardiofacial syndrome minimal critical region. (Correction: vol. 7(4):399). Genome Res. 1997 Jan;7(1):17-26
3J:213451 Karpinski BA, Maynard TM, Fralish MS, Nuwayhid S, Zohn IE, Moody SA, LaMantia AS, Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech. 2014 Feb;7(2):245-57
1*J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:191130 Maynard TM, Gopalakrishna D, Meechan DW, Paronett EM, Newbern JM, Lamantia AS, 22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development. Hum Mol Genet. 2013 Jan 15;22(2):300-12
2*J:74505 Maynard TM, Haskell GT, Bhasin N, Lee JM, Gassman AA, Lieberman JA, LaMantia AS, RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction. Mech Dev. 2002 Feb;111(1-2):177-80
6*J:86704 Maynard TM, Haskell GT, Peters AZ, Sikich L, Lieberman JA, LaMantia AS, A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14433-8
3J:116629 Meechan DW, Maynard TM, Wu Y, Gopalakrishna D, Lieberman JA, Lamantia AS, Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome. Mol Cell Neurosci. 2006 Dec;33(4):412-28
4J:308607 Molinard-Chenu A, Dayer A, The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of Corticogenesis. Biol Psychiatry. 2018 Apr 15;83(8):692-706
1J:235630 Paronett EM, Meechan DW, Karpinski BA, LaMantia AS, Maynard TM, Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation. Cereb Cortex. 2015 Oct;25(10):3977-93
7*J:39611 Taylor C, Wadey R, O'Donnell H, Roberts C, Mattei MG, Kimber WL , Wynshaw-Boris A , Scambler PJ, Cloning and mapping of murine Dgcr2 and its homology to the Sez-12 seizure-related protein. Mamm Genome. 1997 May;8(5):371-5

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory