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Gene Expression Literature Summary
Symbol
Name
ID
Crygc
crystallin, gamma C
MGI:88523

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E12 E12.5 E13.5 E14.5 E15.5 E16 E16.5 E18.5 A
In situ protein (section) 1 2 1
Northern blot 1 1
Western blot 1 2
RT-PCR 1 3 2 3 6 1 2 1 7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Crygc  crystallin, gamma C   (Synonyms: Cryg-5)
Results  Reference
3J:93301 Fujimoto M, Izu H, Seki K, Fukuda K, Nishida T, Yamada S, Kato K, Yonemura S, Inouye S, Nakai A, HSF4 is required for normal cell growth and differentiation during mouse lens development. EMBO J. 2004 Nov 27;23(21):4297-306
2J:58563 Gonzalez M, Ruggiero FP, Chang Q, Shi YJ, Rich MM, Kraner S, Balice-Gordon RJ, Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions [see comments]. Neuron. 1999 Nov;24(3):567-83
5*J:17072 Goring DR, Breitman ML, Tsui LC, Temporal regulation of six crystallin transcripts during mouse lens development. Exp Eye Res. 1992 May;54(5):785-95
1J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60
1*J:80609 Kim SW, Cheong C, Sohn YC, Goo YH, Oh WJ, Park JH, Joe SY, Kang HS, Kim DK, Kee C, Lee JW, Lee HW, Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract. Mol Cell Biol. 2002 Dec;22(24):8409-14
1J:169836 Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL, Mutations in the RNA granule component TDRD7 cause cataract and glaucoma. Science. 2011 Mar 25;331(6024):1571-6
1J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291
6J:95535 Min JN, Zhang Y, Moskophidis D, Mivechi NF, Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis. 2004 Dec;40(4):205-17
2J:46636 Nishiguchi S, Wood H, Kondoh H, Lovell-Badge R, Episkopou V, Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice. Genes Dev. 1998 Mar 15;12(6):776-81
5J:115522 Sandilands A, Hutcheson AM, Long HA, Prescott AR, Vrensen G, Loster J, Klopp N, Lutz RB, Graw J, Masaki S, Dobson CM, MacPhee CE, Quinlan RA, Altered aggregation properties of mutant gamma-crystallins cause inherited cataract. EMBO J. 2002 Nov 15;21(22):6005-14
1J:158257 Takeuchi T, Kudo T, Ogata K, Hamada M, Nakamura M, Kito K, Abe Y, Ueda N, Yamamoto M, Engel JD, Takahashi S, Neither MafA/L-Maf nor MafB is essential for lens development in mice. Genes Cells. 2009 Aug;14(8):941-7
1J:91136 Tasheva ES, Ke A, Deng Y, Jun C, Takemoto LJ, Koester A, Conrad GW, Differentially expressed genes in the lens of mimecan-null mice. Mol Vis. 2004 Jun 17;10:403-16
1J:53431 Wigle JT, Chowdhury K, Gruss P, Oliver G, Prox1 function is crucial for mouse lens-fibre elongation. Nat Genet. 1999 Mar;21(3):318-22
1J:178731 Xie Q, Cvekl A, The Orchestration of Mammalian Tissue Morphogenesis through a Series of Coherent Feed-forward Loops. J Biol Chem. 2011 Dec 16;286(50):43259-71
4*J:163241 Zhao L, Li K, Bao S, Zhou Y, Liang Y, Zhao G, Chen Y, Xiao J, A 1-bp deletion in the gammaC-crystallin leads to dominant cataracts in mice. Mamm Genome. 2010 Aug;21(7-8):361-9

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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory