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Gene Expression Literature Summary
Symbol
Name
ID
Crh
corticotropin releasing hormone
MGI:88496

22 matching records from 22 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E10 E11 E11.5 E12 E12.5 E13 E13.5 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18.5 E A
In situ protein (section) 1 1 1 1 1 1 1 1 5
In situ RNA (section) 1 1 4 2 6 3 2 4 8
RT-PCR 1 1 1 2 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Crh  corticotropin releasing hormone   (Synonyms: corticotropin releasing factor, corticotropin-releasing factor, CRF, LOC383938)
Results  Reference
3J:58466 Acampora D, Postiglione MP, Avantaggiato V, Di Bonito M, Vaccarino FM, Michaud J, Simeone A, Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene. Genes Dev. 1999 Nov 1;13(21):2787-800
6*J:58937 Bishop GA, King JS, Corticotropin releasing factor in the embryonic mouse cerebellum. Exp Neurol. 1999 Dec;160(2):489-99
1J:110638 Catalano SM, Messersmith EK, Goodman CS, Shatz CJ, Chedotal A, Many major CNS axon projections develop normally in the absence of semaphorin III. Mol Cell Neurosci. 1998 Jul;11(4):173-82
1J:58438 Deiner MS, Sretavan DW, Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice. J Neurosci. 1999 Nov 15;19(22):9900-12
1J:196342 Denaxa M, Kalaitzidou M, Garefalaki A, Achimastou A, Lasrado R, Maes T, Pachnis V, Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons. Cell Rep. 2012 Nov 29;2(5):1351-62
1J:157229 Duplan SM, Boucher F, Alexandrov L, Michaud JL, Impact of Sim1 gene dosage on the development of the paraventricular and supraoptic nuclei of the hypothalamus. Eur J Neurosci. 2009 Dec;30(12):2239-49
1J:161632 Garcia-Moreno F, Pedraza M, Di Giovannantonio LG, Di Salvio M, Lopez-Mascaraque L, Simeone A, De Carlos JA, A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nat Neurosci. 2010 Jun;13(6):680-9
1J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86
1J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32
1J:89548 Goshu E, Jin H, Lovejoy J, Marion JF, Michaud JL, Fan CM, Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus. Mol Endocrinol. 2004 May;18(5):1251-62
1J:74118 Hosoya T, Oda Y, Takahashi S, Morita M, Kawauchi S, Ema M, Yamamoto M, Fujii-Kuriyama Y, Defective development of secretory neurones in the hypothalamus of Arnt2-knockout mice. Genes Cells. 2001 Apr;6(4):361-74
1J:191801 Huang CC, Shih MC, Hsu NC, Chien Y, Chung BC, Fetal glucocorticoid synthesis is required for development of fetal adrenal medulla and hypothalamus feedback suppression. Endocrinology. 2012 Oct;153(10):4749-56
8J:18319 Keegan CE, Herman JP, Karolyi IJ, O'Shea KS, Camper SA, Seasholtz AF, Differential expression of corticotropin-releasing hormone in developing mouse embryos and adult brain. Endocrinology. 1994 Jun;134(6):2547-55
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1J:60430 Michaud JL, DeRossi C, May NR, Holdener BC, Fan CM, ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus. Mech Dev. 2000 Feb;90(2):253-61
3J:50772 Michaud JL, Rosenquist T, May NR, Fan CM, Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. Genes Dev. 1998 Oct 15;12(20):3264-75
2J:23082 Muglia L, Jacobson L, Dikkes P, Majzoub JA, Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature. 1995 Feb 2;373(6513):427-32
2J:134188 Reichardt HM, Schutz G, Feedback control of glucocorticoid production is established during fetal development. Mol Med. 1996 Nov;2(6):735-44
1J:155932 Rose MF, Ahmad KA, Thaller C, Zoghbi HY, Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22462-7
7J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134
3J:65759 Wang W, Lufkin T, The murine otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus. Dev Biol. 2000 Nov 15;227(2):432-49
1J:199203 Wu HH, Levitt P, Prenatal expression of MET receptor tyrosine kinase in the fetal mouse dorsal raphe nuclei and the visceral motor/sensory brainstem. Dev Neurosci. 2013;35(1):1-16

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory