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Symbol Name ID |
Braf
Braf transforming gene MGI:88190 |
| Age | E1.5 | E2.5 | E3.5 | E7.5 | E9.5 | E10.5 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17.5 | E | A |
| In situ protein (section) | 1 | 1 | 1 | ||||||||||||||||
| In situ RNA (section) | 1 | 1 | |||||||||||||||||
| In situ protein (whole mount) | 1 | ||||||||||||||||||
| In situ RNA (whole mount) | 1 | ||||||||||||||||||
| Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 2 | ||||||||||||
| Western blot | 1 | 1 | 3 | 1 | 1 | 1 | 1 | 3 | |||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 3 |
| Braf Braf transforming gene (Synonyms: 9930012E13Rik, Braf2, Braf-2, D6Ertd631e) | |
| Results | Reference |
| 5 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
| 3* | J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998; |
| 2 | J:105998 Galabova-Kovacs G, Matzen D, Piazzolla D, Meissl K, Plyushch T, Chen AP, Silva A, Baccarini M, Essential role of B-Raf in ERK activation during extraembryonic development. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1325-30 |
| 1 | J:101397 Gotz R, Wiese S, Takayama S, Camarero GC, Rossoll W, Schweizer U, Troppmair J, Jablonka S, Holtmann B, Reed JC, Rapp UR, Sendtner M, Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells. Nat Neurosci. 2005 Sep;8(9):1169-78 |
| 1* | J:171409 GUDMAP: the GenitoUrinary Development Molecular Anatomy Project, http://www.gudmap.org. 2004; |
| 1 | J:185949 Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB, Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes Dev. 2012 Jul 15;26(14):1626-42 |
| 1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
| 2* | J:10369 Storm SM, Cleveland JL, Rapp UR, Expression of raf family proto-oncogenes in normal mouse tissues. Oncogene. 1990 Mar;5(3):345-51 |
| 4 | J:170095 Urosevic J, Sauzeau V, Soto-Montenegro ML, Reig S, Desco M, Wright EM, Canamero M, Mulero F, Ortega S, Bustelo XR, Barbacid M, Constitutive activation of B-Raf in the mouse germ line provides a model for human cardio-facio-cutaneous syndrome. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5015-20 |
| 1 | J:119299 Voss AK, Krebs DL, Thomas T, C3G regulates the size of the cerebral cortex neural precursor population. EMBO J. 2006 Aug 9;25(15):3652-63 |
| 13* | J:61360 Wojnowski L, Stancato LF, Larner AC, Rapp UR, Zimmer A, Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis. Mech Dev. 2000 Mar 1;91(1-2):97-104 |
| 1* | J:41257 Wojnowski L, Zimmer AM, Beck TW, Hahn H, Bernal R, Rapp UR, Zimmer A, Endothelial apoptosis in Braf-deficient mice [see comments]. Nat Genet. 1997 Jul;16(3):293-7 |
| 5 | J:98531 Xie Y, Wang Y, Sun T, Wang F, Trostinskaia A, Puscheck E, Rappolee DA, Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells. Mol Reprod Dev. 2005 May;71(1):1-11 |
| 5 | J:121660 Zhong J, Li X, McNamee C, Chen AP, Baccarini M, Snider WD, Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo. Nat Neurosci. 2007 May;10(5):598-607 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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