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Gene Expression Literature Summary
Symbol
Name
ID
Actc1
actin, alpha, cardiac muscle 1
MGI:87905

109 matching records from 109 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E6.5 E7 E7.5 E8 E8.5 E9 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E19 E20 E A
In situ protein (section) 2 3 3 1 3 1 1 2 1 1 2 1 1 1 2 1 5
In situ RNA (section) 2 3 2 4 17 2 10 2 13 1 8 5 1 2 5 2 1 1 1 3 1 1 2 2
In situ protein (whole mount) 1
In situ RNA (whole mount) 1 1 3 4 10 1 4 1
Northern blot 1 1 1 1 1 3
Western blot 1 1 1
RT-PCR 1 1 2 1 3 4 8 1 4 1 2 3 2 1 3 3 1 8
cDNA clones 1
RNase protection 1 1
Nuclease S1 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Actc1  actin, alpha, cardiac muscle 1   (Synonyms: Actc-1, alphac-actin)
Results  Reference
3J:50876 Arsenian S, Weinhold B, Oelgeschlager M, Ruther U, Nordheim A, Serum response factor is essential for mesoderm formation during mouse embryogenesis. EMBO J. 1998 Nov 2;17(21):6289-99
2*J:174611 Azhar M, Brown K, Gard C, Chen H, Rajan S, Elliott DA, Stevens MV, Camenisch TD, Conway SJ, Doetschman T, Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn. 2011 Jul 20;
1*J:93087 Bajanca F, Luz M, Duxson MJ, Thorsteinsdottir S, Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage. Dev Dyn. 2004 Oct;231(2):402-15
2J:111623 Barbosky L, Lawrence DK, Karunamuni G, Wikenheiser JC, Doughman YQ, Visconti RP, Burch JB, Watanabe M, Apoptosis in the developing mouse heart. Dev Dyn. 2006 Jul 31;235(9):2592-2602
1J:153091 Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA, Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14932-6
1J:194471 Borensztein M, Monnier P, Court F, Louault Y, Ripoche MA, Tiret L, Yao Z, Tapscott SJ, Forne T, Montarras D, Dandolo L, Myod and H19-Igf2 locus interactions are required for diaphragm formation in the mouse. Development. 2013 Mar;140(6):1231-9
2J:79098 Brennan J, Norris DP, Robertson EJ, Nodal activity in the node governs left-right asymmetry. Genes Dev. 2002 Sep 15;16(18):2339-44
3J:195548 Brody MJ, Hacker TA, Patel JR, Feng L, Sadoshima J, Tevosian SG, Balijepalli RC, Moss RL, Lee Y, Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS One. 2012;7(12):e51621
1J:59924 Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE, Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Dev Biol. 2000 Jan 15;217(2):266-77
1J:79153 Chen F, Kook H, Milewski R, Gitler A, Lu M, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay J, Novotny J, Schwartz R, Harvey R, Mullins M, Epstein J, Hop Is an Unusual Homeobox Gene that Modulates Cardiac Development. Cell. 2002 Sep 20;110(6):713
1J:169957 Chen L, Fulcoli FG, Tang S, Baldini A, Tbx1 regulates proliferation and differentiation of multipotent heart progenitors. Circ Res. 2009 Oct 23;105(9):842-51
1J:57294 Colvin JS, Feldman B, Nadeau JH, Goldfarb M, Ornitz DM, Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Dev Dyn. 1999 Sep;216(1):72-88
1J:46399 de la Pompa JL, Timmerman LA, Takimoto H, Yoshida H, Elia AJ, Samper E, Potter J, Wakeham A, Marengere L, Langille BL, Crabtree GR, Mak TW, Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum [see comments]. Nature. 1998 Mar 12;392(6672):182-6
2*J:12606 deLapeyriere O, Ollendorff V, Planche J, Ott MO, Pizette S, Coulier F, Birnbaum D, Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo. Development. 1993 Jun;118(2):601-11
3*J:4372 Dickson MC, Slager HG, Duffie E, Mummery CL, Akhurst RJ, RNA and protein localisations of TGF beta 2 in the early mouse embryo suggest an involvement in cardiac development. Development. 1993 Feb;117(2):625-39
1J:108510 Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ, Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose. Invest Ophthalmol Vis Sci. 2006 May;47(5):1785-93
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*J:88432 Ding JH, Xu X, Yang D, Chu PH, Dalton ND, Ye Z, Yeakley JM, Cheng H, Xiao RP, Ross J, Chen J, Fu XD, Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart. EMBO J. 2004 Feb 25;23(4):885-96
2*J:4592 Drucker BJ, Goldfarb M, Murine FGF-4 gene expression is spatially restricted within embryonic skeletal muscle and other tissues. Mech Dev. 1993 Mar;40(3):155-63
5J:175544 Dupuis LE, McCulloch DR, McGarity JD, Bahan A, Wessels A, Weber D, Diminich AM, Nelson CM, Apte SS, Kern CB, Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease. Dev Biol. 2011 Sep 1;357(1):152-64
1*J:18124 Edmondson DG, Lyons GE, Martin JF, Olson EN, Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63
1J:93083 Fraidenraich D, Stillwell E, Romero E, Wilkes D, Manova K, Basson CT, Benezra R, Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science. 2004 Oct 8;306(5694):247-52
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1J:191565 Grote P, Wittler L, Hendrix D, Koch F, Wahrisch S, Beisaw A, Macura K, Blass G, Kellis M, Werber M, Herrmann BG, The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
4*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
1J:132079 Gustafson-Wagner EA, Sinn HW, Chen YL, Wang DZ, Reiter RS, Lin JL, Yang B, Williamson RA, Chen J, Lin CI, Lin JJ, Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2680-92
1J:190992 Harmelink C, Peng Y, DeBenedittis P, Chen H, Shou W, Jiao K, Myocardial Mycn is essential for mouse ventricular wall morphogenesis. Dev Biol. 2013 Jan 1;373(1):53-63
1J:122471 Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP, Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F, Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Mol Genet Metab. 2007 Jul;91(3):285-93
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1J:121230 Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM, Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev. 2007 May 1;21(9):1098-112
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2J:20550 Kastner P, Grondona JM, Mark M, Gansmuller A, LeMeur M, Decimo D, Vonesch JL, Dolle P, Chambon P, Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell. 1994 Sep 23;78(6):987-1003
2*J:2819 Keller A, Ott MO, Lamande N, Lucas M, Gros F, Buckingham M, Lazar M, Activation of the gene encoding the glycolytic enzyme beta-enolase during early myogenesis precedes an increased expression during fetal muscle development. Mech Dev. 1992 Jul;38(1):41-54
2J:159721 Kern CB, Wessels A, McGarity J, Dixon LJ, Alston E, Argraves WS, Geeting D, Nelson CM, Menick DR, Apte SS, Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies. Matrix Biol. 2010 May;29(4):304-16
1J:161758 Kiefer SM, Robbins L, Barina A, Zhang Z, Rauchman M, SALL1 truncated protein expression in Townes-Brocks syndrome leads to ectopic expression of downstream genes. Hum Mutat. 2008 Sep;29(9):1133-40
2J:96055 Kochilas LK, Li J, Jin F, Buck CA, Epstein JA, p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium. Pediatr Res. 1999 May;45(5 Pt 1):635-42
1J:75968 Koga H, Kaji Y, Nishii K, Shirai M, Tomotsune D, Osugi T, Sawada A, Kim JY, Hara J, Miwa T, Yamauchi-Takihara K, Shibata Y, Takihara Y, Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy. Lab Invest. 2002 Apr;82(4):375-85
1J:105332 Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG, Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat Genet. 2006 Feb;38(2):175-183
1J:155281 Krishnan J, Ahuja P, Bodenmann S, Knapik D, Perriard E, Krek W, Perriard JC, Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function. Circ Res. 2008 Nov 7;103(10):1139-46
1*J:86837 Kuwahara K, Saito Y, Takano M, Arai Y, Yasuno S, Nakagawa Y, Takahashi N, Adachi Y, Takemura G, Horie M, Miyamoto Y, Morisaki T, Kuratomi S, Noma A, Fujiwara H, Yoshimasa Y, Kinoshita H, Kawakami R, Kishimoto I, Nakanishi M, Usami S, Saito Y, Harada M, Nakao K, NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. EMBO J. 2003 Dec 1;22(23):6310-21
2J:175025 Lai D, Liu X, Forrai A, Wolstein O, Michalicek J, Ahmed I, Garratt AN, Birchmeier C, Zhou M, Hartley L, Robb L, Feneley MP, Fatkin D, Harvey RP, Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium. Circ Res. 2010 Sep 17;107(6):715-27
1J:62182 Lai KM, Pawson T, The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo. Genes Dev. 2000 May 1;14(9):1132-45
2J:138814 Lavine KJ, Long F, Choi K, Smith C, Ornitz DM, Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development. Development. 2008 Sep;135(18):3161-71
2J:63359 Lee Y, Song AJ, Baker R, Micales B, Conway SJ, Lyons GE, Jumonji, a nuclear protein that is necessary for normal heart development [see comments]. Circ Res. 2000 May 12;86(9):932-8
1*J:114492 Li J, Stouffs M, Serrander L, Banfi B, Bettiol E, Charnay Y, Steger K, Krause KH, Jaconi ME, The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation. Mol Biol Cell. 2006 Sep;17(9):3978-88
1J:171220 Li P, Cavallero S, Gu Y, Chen TH, Hughes J, Hassan AB, Bruning JC, Pashmforoush M, Sucov HM, IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. 2011 May;138(9):1795-805
1J:159110 Li P, Pashmforoush M, Sucov HM, Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation. Dev Cell. 2010 Mar 16;18(3):480-5
3J:135407 Liao J, Aggarwal VS, Nowotschin S, Bondarev A, Lipner S, Morrow BE, Identification of downstream genetic pathways of Tbx1 in the second heart field. Dev Biol. 2008 Apr 15;316(2):524-37
2J:94180 Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG, Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature. 2004 Nov 4;432(7013):107-12
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2J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82
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3*J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104
1*J:165465 Sehic A, Risnes S, Khan QE, Khuu C, Osmundsen H, Gene expression and dental enamel structure in developing mouse incisor. Eur J Oral Sci. 2010 Apr;118(2):118-30
1J:79152 Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN, Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell. 2002 Sep 20;110(6):725-35
1J:78065 Shirai M, Osugi T, Koga H, Kaji Y, Takimoto E, Komuro I, Hara J, Miwa T, Yamauchi-Takihara K, Takihara Y, The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis. J Clin Invest. 2002 Jul;110(2):177-84
3*J:81324 Smart N, Hill AA, Cross JC, Riley PR, A differential screen for putative targets of the bHLH transcription factor Hand1 in cardiac morphogenesis. Mech Dev. 2002 Dec;119 Suppl 1:S65-71
1J:98489 Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, Solloway MJ, McCulley DJ, Leimena C, Preis JI, Dunwoodie SL, Elliott DE, Prall OW, Black BL, Fatkin D, Harvey RP, Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
1J:205662 Takeuchi JK, Lou X, Alexander JM, Sugizaki H, Delgado-Olguin P, Holloway AK, Mori AD, Wylie JN, Munson C, Zhu Y, Zhou YQ, Yeh RF, Henkelman RM, Harvey RP, Metzger D, Chambon P, Stainier DY, Pollard KS, Scott IC, Bruneau BG, Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun. 2011;2:187
2*J:57069 Takeuchi T, Kojima M, Nakajima K, Kondo S, jumonji gene is essential for the neurulation and cardiac development of mouse embryos with a C3H/He background. Mech Dev. 1999 Aug;86(1-2):29-38
2*J:52597 Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S, The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 1999 Mar;126(6):1269-80
1J:186268 Vincent SD, Mayeuf A, Niro C, Saitou M, Buckingham M, Non Conservation of Function for the Evolutionarily Conserved Prdm1 Protein in the Control of the Slow Twitch Myogenic Program in the Mouse Embryo. Mol Biol Evol. 2012 May 13;
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1J:169047 Wang J, Greene SB, Bonilla-Claudio M, Tao Y, Zhang J, Bai Y, Huang Z, Black BL, Wang F, Martin JF, Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism. Dev Cell. 2010 Dec 14;19(6):903-12
1J:95388 Wang X, Merritt AJ, Seyfried J, Guo C, Papadakis ES, Finegan KG, Kayahara M, Dixon J, Boot-Handford RP, Cartwright EJ, Mayer U, Tournier C, Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway. Mol Cell Biol. 2005 Jan;25(1):336-45
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last database update
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