Gene Expression Literature Summary

• Symbol: Senp1
• Name: SUMO1/sentrin specific peptidase 1
• ID: MGI:2445054

7 matching records from 7 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E17.5	E18.5	E19.5	E	P
Immunohistochemistry (section)		1			1		1	1		1		1
In situ RNA (section)						1
In situ reporter (knock in)				1
Western blot				1		1			1			4
RT-PCR	1	1	1	1		1					1	1
cDNA clones				1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Senp1  SUMO1/sentrin specific peptidase 1   (Synonyms: 2310046A20Rik, D15Ertd528e, E330036L07Rik)
Results	Reference
3	J:141453 Cheng J, Kang X, Zhang S, Yeh ET, SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell. 2007 Nov 2;131(3):584-95
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:99175 Yamaguchi T, Sharma P, Athanasiou M, Kumar A, Yamada S, Kuehn MR, Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Mol Cell Biol. 2005 Jun;25(12):5171-82
2	J:331482 Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J, Xu D, SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation. Nat Commun. 2022 Nov 22;13(1):7153
2	J:276133 Yang CY, Yu TH, Wen WL, Ling P, Hsu KS, Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation. J Neurosci. 2019 Jun 19;39(25):4959-4975
5	J:321201 Yang K, Shi Y, Du X, Wang J, Zhang Y, Shan S, Yuan Y, Wang R, Zhou C, Liu Y, Cai Z, Wang Y, Fan L, Xu H, Yu J, Cheng J, Li F, Qiu Z, SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice. Cell Rep. 2021 Nov 2;37(5):109939
6*	J:298019 Zhang X, Wang C, Zhao D, Chen X, Zhang C, Zheng J, Liu X, Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression. PLoS One. 2020;15(11):e0242606