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Gene Expression Literature Summary
Symbol
Name
ID
Sumo2
small ubiquitin-like modifier 2
MGI:2158813

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14.5 E15.5 E16.5 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 2 1 1 1 1 1 1 1 2
In situ RNA (whole mount) 1 1 1 2 1 1
Western blot 1 1 1 2 1 1 1 3 4
RT-PCR 1 2 1 1 2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sumo2  small ubiquitin-like modifier 2   (Synonyms: Smt3b, Smt3h2)
Results  Reference
1J:141453 Cheng J, Kang X, Zhang S, Yeh ET, SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell. 2007 Nov 2;131(3):584-95
6*J:177922 Costa MW, Lee S, Furtado MB, Xin L, Sparrow DB, Martinez CG, Dunwoodie SL, Kurtenbach E, Mohun T, Rosenthal N, Harvey RP, Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5. PLoS One. 2011;6(9):e24812
1J:141678 Evdokimov E, Sharma P, Lockett SJ, Lualdi M, Kuehn MR, Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. J Cell Sci. 2008 Dec 15;121(Pt 24):4106-13
8*J:208871 Gong L, Ji WK, Hu XH, Hu WF, Tang XC, Huang ZX, Li L, Liu M, Xiang SH, Wu E, Woodward Z, Liu YZ, Nguyen QD, Li DW, Sumoylation differentially regulates Sp1 to control cell differentiation. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5574-9
9J:215364 Hasegawa Y, Yoshida D, Nakamura Y, Sakakibara S, Spatiotemporal distribution of SUMOylation components during mouse brain development. J Comp Neurol. 2014 Sep 1;522(13):3020-36
1J:162938 Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET, SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell. 2010 Apr 23;38(2):191-201
1J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49
1J:260447 Usui N, Araujo DJ, Kulkarni A, Co M, Ellegood J, Harper M, Toriumi K, Lerch JP, Konopka G, Foxp1 regulation of neonatal vocalizations via cortical development. Genes Dev. 2017 Oct 15;31(20):2039-2055
8*J:217019 Wang L, Wansleeben C, Zhao S, Miao P, Paschen W, Yang W, SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development. EMBO Rep. 2014 Aug;15(8):878-85
2J:99175 Yamaguchi T, Sharma P, Athanasiou M, Kumar A, Yamada S, Kuehn MR, Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Mol Cell Biol. 2005 Jun;25(12):5171-82
1*J:166958 Yates LL, Papakrivopoulou J, Long DA, Goggolidou P, Connolly JO, Woolf AS, Dean CH, The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation. Hum Mol Genet. 2010 Dec 1;19(23):4663-76
1J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110

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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory