Gene Expression Literature Summary

• Symbol: Slc26a5
• Name: solute carrier family 26, member 5
• ID: MGI:1933154

27 matching records from 27 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E12.5	E14	E14.5	E17	E18	E19	P
Immunohistochemistry (section)									14
In situ RNA (section)					1				1
Immunohistochemistry (whole mount)									7
Northern blot				1					1
RT-PCR	1	1	1	1		1	1	1	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Slc26a5  solute carrier family 26, member 5   (Synonyms: Pres, prestin)
Results	Reference
4*	J:24458 Bar I, Lambert De Rouvroit C, Royaux I, Krizman DB, Dernoncourt C, Ruelle D, Beckers MC, Goffinet AM, A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments. Genomics. 1995 Apr 10;26(3):543-9
1	J:274697 Celaya AM, Sanchez-Perez I, Bermudez-Munoz JM, Rodriguez-de la Rosa L, Pintado-Berninches L, Perona R, Murillo-Cuesta S, Varela-Nieto I, Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss. Elife. 2019 Apr 2;8:e39159
1	J:306028 Chen T, Rohacek AM, Caporizzo M, Nankali A, Smits JJ, Oostrik J, Lanting CP, Kucuk E, Gilissen C, van de Kamp JM, Pennings RJE, Rakowiecki SM, Kaestner KH, Ohlemiller KK, Oghalai JS, Kremer H, Prosser BL, Epstein DJ, Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. Dev Cell. 2021 May 17;56(10):1526-1540.e7
1	J:267727 Chessum L, Matern MS, Kelly MC, Johnson SL, Ogawa Y, Milon B, McMurray M, Driver EC, Parker A, Song Y, Codner G, Esapa CT, Prescott J, Trent G, Wells S, Dragich AK, Frolenkov GI, Kelley MW, Marcotti W, Brown SDM, Elkon R, Bowl MR, Hertzano R, Helios is a key transcriptional regulator of outer hair cell maturation. Nature. 2018 Nov;563(7733):696-700
2	J:311815 Chumak T, Bohuslavova R, Macova I, Dodd N, Buckiova D, Fritzsch B, Syka J, Pavlinkova G, Deterioration of the Medial Olivocochlear Efferent System Accelerates Age-Related Hearing Loss in Pax2-Isl1 Transgenic Mice. Mol Neurobiol. 2016 May;53(4):2368-83
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:276652 Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F, Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
1	J:321815 Filova I, Bohuslavova R, Tavakoli M, Yamoah EN, Fritzsch B, Pavlinkova G, Early Deletion of Neurod1 Alters Neuronal Lineage Potential and Diminishes Neurogenesis in the Inner Ear. Front Cell Dev Biol. 2022;10:845461
1	J:311887 Filova I, Dvorakova M, Bohuslavova R, Pavlinek A, Elliott KL, Vochyanova S, Fritzsch B, Pavlinkova G, Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers. Mol Neurobiol. 2020 Dec;57(12):5307-5323
1	J:333967 Filova I, Pysanenko K, Tavakoli M, Vochyanova S, Dvorakova M, Bohuslavova R, Smolik O, Fabriciova V, Hrabalova P, Benesova S, Valihrach L, Cerny J, Yamoah EN, Syka J, Fritzsch B, Pavlinkova G, ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2207433119
1	J:330325 Garcia-Anoveros J, Clancy JC, Foo CZ, Garcia-Gomez I, Zhou Y, Homma K, Cheatham MA, Duggan A, Tbx2 is a master regulator of inner versus outer hair cell differentiation. Nature. 2022 May;605(7909):298-303
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:311164 Hayashi Y, Chiang H, Tian C, Indzhykulian AA, Edge ASB, Norrie disease protein is essential for cochlear hair cell maturation. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2106369118
1*	J:332214 Kaiser M, Ludtke TH, Deuper L, Rudat C, Christoffels VM, Kispert A, Trowe MO, TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti. Nat Commun. 2022 Dec 9;13(1):7628
1*	J:112915 Kruger M, Schmid T, Kruger S, Bober E, Braun T, Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci. 2006 Sep;24(6):1581-90
1	J:142574 Legendre K, Safieddine S, Kussel-Andermann P, Petit C, El-Amraoui A, alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells. J Cell Sci. 2008 Oct 15;121(Pt 20):3347-56
3*	J:151359 Lelli A, Asai Y, Forge A, Holt JR, Geleoc GS, Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea. J Neurophysiol. 2009 Jun;101(6):2961-73
1*	J:282727 Li C, Shu Y, Wang G, Zhang H, Lu Y, Li X, Li G, Song L, Liu Z, Characterizing a novel vGlut3-P2A-iCreER knockin mouse strain in cochlea. Hear Res. 2018 Jul;364:12-24
1	J:336865 Li S, He S, Lu Y, Jia S, Liu Z, Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development. Cell Rep. 2023 May 30;42(5):112504
1	J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119
1*	J:278471 Nakanishi H, Kurima K, Pan B, Wangemann P, Fitzgerald TS, Geleoc GS, Holt JR, Griffith AJ, Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. Sci Rep. 2018 Aug 14;8(1):12125
1*	J:287221 Partearroyo T, Murillo-Cuesta S, Vallecillo N, Bermudez-Munoz JM, Rodriguez-de la Rosa L, Mandruzzato G, Celaya AM, Zeisel SH, Pajares MA, Varela-Moreiras G, Varela-Nieto I, Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia. FASEB J. 2019 May;33(5):5942-5956
1	J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442
1	J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695
1	J:278320 Wolter S, Mohrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Kramer M, Feil R, Pilz PKD, Knipper M, Ruttiger L, GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing. Front Neural Circuits. 2018;12:65
1	J:273440 Zak M, van Oort T, Hendriksen FG, Garcia MI, Vassart G, Grolman W, LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea. Front Cell Neurosci. 2016;10:186
6	J:81871 Zheng J, Long KB, Matsuda KB, Madison LD, Ryan AD, Dallos PD, Genomic characterization and expression of mouse prestin, the motor protein of outer hair cells. Mamm Genome. 2003 Feb;14(2):87-96