Gene Expression Literature Summary

• Symbol: Bco1
• Name: beta-carotene oxygenase 1
• ID: MGI:1926923

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8.5	E9.5	E10.5	E11	E12.5	E13	E14.5	E15	E17.5	P
In situ RNA (section)			1	1						1			2
Northern blot		1					1		1		1		2
Western blot			1		1	1		1		1			2
RT-PCR	1		1	1	2	2		1		3		1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bco1  beta-carotene oxygenase 1   (Synonyms: Bcdo, Bcdo1, Bcmo1, beta-CD, betaCMOOX, Cmoi)
Results	Reference
1	J:203823 Billings SE, Pierzchalski K, Butler Tjaden NE, Pang XY, Trainor PA, Kane MA, Moise AR, The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. FASEB J. 2013 Dec;27(12):4877-89
14*	J:172777 Kim YK, Wassef L, Chung S, Jiang H, Wyss A, Blaner WS, Quadro L, beta-Carotene and its cleavage enzyme beta-carotene-15,15'-oxygenase (CMOI) affect retinoid metabolism in developing tissues. FASEB J. 2011 May;25(5):1641-52
1*	J:230265 Kim YK, Zuccaro MV, Costabile BK, Rodas R, Quadro L, Tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice. Arch Biochem Biophys. 2015 Apr 15;572:11-8
1	J:190746 Osuala K, Baker CN, Nguyen HL, Martinez C, Weinshenker D, Ebert SN, Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism. Physiol Genomics. 2012 Oct 2;44(19):934-47
5*	J:71041 Paik J, During A, Harrison EH, Mendelsohn CL, Lai K, Blaner WS, Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids. J Biol Chem. 2001 Aug 24;276(34):32160-8
6*	J:67765 Redmond TM, Gentleman S, Duncan T, Yu S, Wiggert B, Gantt E, Cunningham FX Jr, Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase. J Biol Chem. 2001 Mar 2;276(9):6560-5
3*	J:132176 Seino Y, Miki T, Kiyonari H, Abe T, Fujimoto W, Kimura K, Takeuchi A, Takahashi Y, Oiso Y, Iwanaga T, Seino S, Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression. J Biol Chem. 2008 Feb 22;283(8):4905-11
2	J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6